scholarly journals MARPE for the treatment and cure of OSAS: Aruba experience

2020 ◽  
Vol 11 (5) ◽  
pp. 103-107
Author(s):  
Abdal Hadi Kawaiah ◽  
Ananda Kumar Kondepati ◽  
Shalini Devaprasad Pasumarthi ◽  
Tulika Mishra ◽  
Pratik Kumar Singh ◽  
...  
Keyword(s):  
Airway Pressure ◽  
Positive Airway Pressure ◽  
Sleep Apnea Syndrome ◽  
Upper Airway ◽  
Palatal Expansion ◽  
Rapid Palatal Expansion ◽  
Maxillomandibular Advancement ◽  
Obstructive Sleep ◽  
Mandibular Repositioning Appliance ◽  
Apnea Syndrome

Obstructive sleep apnea syndrome (OSAS) is defined as “the stoppage of ventilation or incidence of significant hypoventilation during sleep, which is characterized by episodes of partial or complete upper airway obstruction related with hypoxemia and/or hypercarbia. There have been many treatments reported for this syndrome including Mandibular repositioning appliance (MRA), continuous positive airway pressure (CPAP), weight loss, exercise, intraoral appliance therapy, soft tissue procedures, and maxillomandibular advancement (MMA) surgery. Present study is an attempt where three patients of OSAS have been treated withMiniscrew-assisted rapid palatal expansion (MARPE). The results of BMI, AHI index showed the promising effect. Even the use of MARPE has improved the air flow and increased the rapid palatal area.

scholarly journals Health Preference Measures in Patients with Obstructive Sleep Apnea Syndrome Undergoing Continuous Positive Airway Pressure Therapy: Data from a Randomized Trial

Respiration ◽  
2021 ◽  
Vol 100 (4) ◽  
pp. 328-338
Author(s):  
Fabienne L. Huber ◽  
Michael Furian ◽  
Malcolm Kohler ◽  
Tsogyal D. Latshang ◽  
Yvonne Nussbaumer-Ochsner ◽  
...  
Keyword(s):  
Airway Pressure ◽  
Standard Gamble ◽  
Positive Airway Pressure ◽  
Short Form ◽  
Sleep Apnea Syndrome ◽  
Cpap Therapy ◽  
Trade Off ◽  
Health Preference ◽  
Obstructive Sleep ◽  
Apnea Syndrome

<b><i>Background:</i></b> In patients with obstructive sleep apnea syndrome (OSAS), the preference-based, health-related quality of life in terms of utility has not been extensively studied. <b><i>Objective:</i></b> To address this point, we compared the performance of different instruments assessing utility in patients with OSAS undergoing continuous positive airway pressure (CPAP) therapy. <b><i>Materials and Methods:</i></b> Data of 208 patients with OSAS (28 women, mean ± SE age 54.4 ± 0.7 years, apnea-hypopnea index (AHI) 51.9 ± 1.8/h, Epworth sleepiness score 13.4 ± 0.2) participating in a randomized trial of different CPAP modalities over 2 years were analyzed. Evaluations included sleep studies, Epworth sleepiness scale, and several utility instruments that measure subjective health preference on a scale ranging from 1 (most preferred and perfect health) to 0 (least preferred and very poor health). <b><i>Results:</i></b> After 2 years of CPAP therapy, the mean ± SE AHI was 6.7 ± 1.5/h and Epworth score 7.9 ± 0.4, both <i>p</i> &#x3c; 0.001 versus baseline. Baseline utilities and changes (95% confidence interval) after 2 years of CPAP therapy were EuroQol 5-dimensions 0.79 ± 0.01, 0.02 (0.00–0.05, <i>p</i> = 0.064); short-form 6-dimension medical outcome questionnaire 0.72 ± 0.01, 0.06 (0.04–0.08, <i>p</i> &#x3c; 0.001); Euro-thermometer visual analog scale 0.70 ± 0.01, 0.09 (0.07–0.12, <i>p</i> &#x3c; 0.001); time trade-off 0.82 ± 0.01, 0.03 (0.01–0.06, <i>p</i> = 0.002); and standard gamble 0.82 ± 0.01, −0.01 (−0.03 to 0.02, <i>p</i> = 0.712). <b><i>Conclusion:</i></b> The short-form 6-dimensions questionnaire, the Euro-thermometer, and the time trade-off instruments reflected the major clinical improvements in OSAS, while the EuroQoL 5-dimensions and standard gamble tests were not sensitive to CPAP effects. These results indicate that the evaluation of utility of a treatment for OSAS depends critically on the instrument used, which is important from an individual and societal perspective.

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