Analysis of mediastinal lesions: a study of 27 cases

Background: Mediastinum is a site of non-neoplastic and neoplastic lesions, many of which present as mediastinal masses. The purpose of this study was to study our institutional experience of mediastinal lesions on fine needle aspiration cytology or biopsy. Materials and Methods: This was a retrospective study of 27 patients, who had undergone fine needle aspiration cytology or biopsy for mediastinal lesions from April 2009 to November 2010 in the Department of Pathology, Institute of Medicine, Tribhuwan University Teaching Hospital. All details of the patients pertinent clinical history was obtained from case record file in the department. Results: Out of 27 cases, 18 cases (66.6%) were benign and 7 (26%) were malignant and 2 (7.4%) were inconclusive. Among the malignant lesions, primary tumors constituted 71.5% of cases while metastases were 28.5%. Most of the lesions were seen in the anterior compartment followed by the posterior compartment. Age range was 4 months to 70 years with a mean age of 35.5 years. Thymoma (8 cases) was the commonest lesion seen in mediastinum followed by germ cell tumor and neurogenic tumor. Conclusion: Benign mediastinal lesions are more common than malignant lesions with thymoma being the most commonly diagnosed mediastinal lesion. Keywords: Mediastinum; Germ cell tumor; Thymoma; Non Hodgkin Lymphoma DOI: http://dx.doi.org/10.3126/jpn.v1i2.5404 JPN 2011; 1(2): 114-117

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Testicular Mixed Germ Cell Tumor Diagnosed on Fine Needle Aspiration Cytology - Is It Reliable?

International Journal of Science and Research (IJSR) ◽

10.21275/art2020827 ◽

2019 ◽

Vol 8 (8) ◽

pp. 2239-2241

Author(s):

Richa Garg ◽

Sunil Gupta

Keyword(s):

Germ Cell ◽

Germ Cell Tumor ◽

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Needle Aspiration ◽

Cell Tumor ◽

Aspiration Cytology ◽

Fine Needle ◽

Mixed Germ Cell Tumor ◽

Needle Aspiration Cytology

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Germ cell tumor of ovary with plenty of sarcoid like granulomas: A diagnosis on fine needle aspiration cytology

Journal of Cytology ◽

10.4103/0970-9371.101183 ◽

2012 ◽

Vol 29 (3) ◽

pp. 211 ◽

Cited By ~ 4

Author(s):

ReshmaS Davanageri ◽

HemaB Bannur ◽

RajkumarD Mastiholimath ◽

PrakashV Patil ◽

SunitaY Patil ◽

...

Keyword(s):

Germ Cell ◽

Germ Cell Tumor ◽

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Needle Aspiration ◽

Cell Tumor ◽

Aspiration Cytology ◽

Fine Needle ◽

Needle Aspiration Cytology

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COMPUTED TOMOGRAPHY CORRELATION OF THORACIC LESIONS WITH TRANSTHORACIC FINE NEEDLE ASPIRATION CYTOLOGY AND BIOPSY

SRMS Journal of Medical Science ◽

10.21761/jms.v2i02.2 ◽

2019 ◽

Vol 2 (2) ◽

Author(s):

Rajneesh Madhok ◽

Ashish Gupta ◽

Lalit Singh ◽

Tanu Agarwal

Keyword(s):

Fine Needle Aspiration ◽

Predictive Value ◽

Fine Needle Aspiration Cytology ◽

Needle Aspiration ◽

Aspiration Cytology ◽

Ct Guided ◽

Fine Needle ◽

Malignant Lesions ◽

Needle Aspiration Cytology ◽

Adequate Tissue

INTRODUCTION: The study is an attempt to evaluate the sensitivity, specificity, positive predictive value, negative predictive value, p Value and complications of CT guided thoracic interventions fine needle aspiration cytology and core biopsy which are used for diagnosing benign and malignant thoracic lesions. MATERIAL AND METHODS: Study included 102 Patients (87 males and 15 females) with age group ranged from 15 to 87 years.A total of 143 CT guided interventions (84 FNAC’s and 59 core biopsies) were performed in 102 patients. The tissue obtained was sent to the laboratory for histopathological and cytological analysis for a final diagnosis which would contribute to patient management. RESULTS: All( 59) core biopsies were successful in procuring adequate tissue for histopathological analysis and the yield of core biopsies was 100% .However out of 84 FNAC’s only 4 were unsuccessful in procuring adequate tissue with a failure rate of 4.8%. Post procedural biopsy complications were only three (2.1%) which were small pneumothorax. There were 75 malignant lesions and 23 benign lesions based on cytology and histopathology (4 were excluded due to inadequate sample). There was good agreement between benign and malignant lesions diagnosed on CT and that diagnosed by pathology. The most common benign and malignant lesions were granulomatous lesion and squamous cell carcinoma. CONCLUSION: Percutaneous CT guided interventions like core biopsy and fine needle aspirations cytology are simple minimal invasive procedures with good patient acceptance and low morbidity and almost negligible mortality. CT guided interventions should be performed early for diagnosis of thoracic lesions.

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