scholarly journals Spontaneous thrombosis of neonatal vein of Galen malformation

2009 ◽  
Vol 27 (5) ◽  
pp. E12 ◽  
Author(s):  
Parham Moftakhar ◽  
Moise Danielpour ◽  
Marcel Maya ◽  
Michael J. Alexander

Vein of Galen malformations are rare congenital intracranial vascular malformations. Based on reports in the literature, spontaneous thrombosis or regression of these lesions is rare. Patients have variable outcomes from an asymptomatic course to death. The reasons behind spontaneous thrombosis are not entirely understood. Here the authors present a case of an infant diagnosed with a vein of Galen malformation in utero that subsequently went on to thrombose or regress. A review of the published cases on this phenomenon and the potential causality are discussed.

Author(s):  
Matthew McInnes ◽  
Katherine Fong ◽  
Andrea Grin ◽  
Karel ter Brugge ◽  
Susan Blaser ◽  
...  

Background:Dural sinus malformation (DSM) is a term used to describe congenital vascular malformations characterized by massive dilation of one or more dural sinuses: these dilatations are typically associated with arteriovenous shunts. Such malformations can present antenatally but their early natural history and anatomy is poorly defined.Methods:We reviewed five years of autopsy experience and retrieved three primary vascular malformations of the fetal dural sinuses with ultrasound, magnetic resonance imaging (MRI) and post-mortem correlation.Results:Fetal ultrasound and MRI obtained between 19 and 23 weeks gestational age demonstrated in all cases dilation of the dural sinuses. In two cases vascular thromboses were present in either the dilated dural sinus (one of three) or the associated arteriovenous fistula (one of three). All cases were autopsied at 22-23 weeks gestational age. In one there was imaging and autopsy evidence of remodeling of the dural sinuses associated with a pial arteriovenous fistula. In two cases, no arteriovenous malformation was identified on initial imaging, but only became evident at autopsy. One case showed morphological overlap with vein of Galen aneurysmal malformation, with a midline arteriovenous shunt and vein of Galen ectasia. The other demonstrated a perisylvian dural arteriovenous fistula.Conclusion:In utero thrombosis of feeding vascular malformations or of the dural sinus malformation may be prominent. The early in utero developmental trajectory of dural sinus malformation (DSM) is poorly defined and deserves further study.


2011 ◽  
Vol 15 (2) ◽  
pp. 42-44
Author(s):  
F Ismail ◽  
N Khan ◽  
I Van de Werke ◽  
R Ahmed

Vein of Galen malformations (VGMs) are rare anomalies of intracranial circulation that constitute 1% of all intracranial vascular malformations. We describe a case of severe encephalomalacia associated with a VGM, which has not been previously described.


2016 ◽  
Vol 11 (3) ◽  
pp. 264
Author(s):  
KalpanaDevi Kariyappa ◽  
Murali Krishnaswami ◽  
Francis Gnanaprakasam ◽  
Madan Ramachandran ◽  
Visvanathan Krishnaswamy

Author(s):  
Luis Fernando Pulido ◽  
Diana Murcia Salazar ◽  
Diego Gómez Amarillo ◽  
Juan Nicolás Useche ◽  
Kemel A. Ghotme

2015 ◽  
Vol 09 (02) ◽  
pp. 243-246
Author(s):  
Suyash Mohan ◽  
Ashish Verma ◽  
Gagan Sharma ◽  
Rajendra Phadke

2016 ◽  
Vol 11 (1) ◽  
pp. 74 ◽  
Author(s):  
Dwarakanath Srinivas ◽  
ChandanB Mohanty ◽  
Somanna Sampath

2006 ◽  
Vol 64 (3b) ◽  
pp. 862-864 ◽  
Author(s):  
Robinson M. Marques ◽  
Carlos A.F. Lobão ◽  
Viviane S. Sassaki ◽  
Luiz R. Aguiar

Vein of Galen aneurysm is a rare pathology, representing less than 1% of intracranial vascular malformations. We report on a 65 years-old man who experienced a generalized tonic-clonic seizure. Brain imaging showed a large calcified expanding mass in the pineal region, confirming the diagnosis of a vein of Galen aneurysm. Because of the spontaneous thrombosis of the malformation, there was no need for microsurgical or endovascular treatment and he is been regularly followed since that.


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