scholarly journals Erratum. Management of thoracic spinal cord injury in a professional American football athlete: illustrative case

2021 ◽  
Vol 2 (14) ◽  
Author(s):  
Joseph C. Maroon
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
American Football ◽  
Illustrative Case ◽  
Thoracic Spinal Cord ◽  
Thoracic Spinal ◽  
Cord Injury

scholarly journals Management of thoracic spinal cord injury in a professional American football athlete: illustrative case

2021 ◽  
Vol 2 (6) ◽  
Author(s):  
Joseph C. Maroon ◽  
Andrew Faramand ◽  
Nitin Agarwal ◽  
Amanda L. Harrington ◽  
Vikas Agarwal ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Treatment Protocol ◽  
Football Player ◽  
American Football ◽  
High Dose ◽  
Illustrative Case ◽  
Thoracic Spinal Cord ◽  
Thoracic Spinal ◽  
Cord Injury

BACKGROUND A case of catastrophic thoracic spinal cord injury (SCI) sustained by a professional American football player with severe scoliosis is presented. OBSERVATIONS A 25-year-old professional football player sustained an axial loading injury while tackling. Examination revealed a T8 American Spinal Injury Association Impairment Scale grade A complete SCI. Methylprednisolone and hypothermia protocols were initiated. Computed tomography scan of the thoracic spine demonstrated T8 and T9 facet fractures on the left at the apex of a 42° idiopathic scoliotic deformity. Magnetic resonance imaging (MRI) demonstrated T2 spinal cord hyperintensity at T9. He regained trace movement of his right lower extremity over 12 hours, which was absent on posttrauma day 2. Repeat MRI revealed interval cord compression and worsening of T2 signal change at T7-T8 secondary to hematoma. Urgent decompression and fusion from T8 to T10 were performed. Additional treatment included high-dose omega-3 fatty acids and hyperbaric oxygen therapy. A 2-month inpatient spinal cord rehabilitation program was followed by prolonged outpatient physical therapy. He currently can run and jump with minimal residual distal left lower limb spasticity. LESSONS This is the first known football-related thoracic SCI with idiopathic scoliosis. Aggressive medical and surgical intervention with intensive rehabilitation formed the treatment protocol, with a favorable outcome achieved.

Effect of thoracic spinal cord injury on forelimb somatosensory evoked potential

2021 ◽  
Author(s):  
Angelo H. All ◽  
Shiyu Luo ◽  
Xiaogang Liu ◽  
Hasan Al-Nashash
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Evoked Potential ◽  
Somatosensory Evoked Potential ◽  
Thoracic Spinal Cord ◽  
Thoracic Spinal ◽  
Cord Injury

scholarly journals Sonic Hedgehog modulates the inflammatory response and improves functional recovery after spinal cord injury in a thoracic contusion–compression model

2021 ◽  
Author(s):  
Hao Zhang ◽  
Alexander Younsi ◽  
Guoli Zheng ◽  
Mohamed Tail ◽  
Anna-Kathrin Harms ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Sonic Hedgehog ◽  
Functional Recovery ◽  
Intrathecal Administration ◽  
Neuroprotective Effects ◽  
Thoracic Spinal Cord ◽  
Shh Pathway ◽  
Thoracic Spinal ◽  
Cord Injury

Abstract Purpose The Sonic Hedgehog (Shh) pathway has been associated with a protective role after injury to the central nervous system (CNS). We, therefore, investigated the effects of intrathecal Shh-administration in the subacute phase after thoracic spinal cord injury (SCI) on secondary injury processes in rats. Methods Twenty-one Wistar rats were subjected to thoracic clip-contusion/compression SCI at T9. Animals were randomized into three treatment groups (Shh, Vehicle, Sham). Seven days after SCI, osmotic pumps were implanted for seven-day continuous intrathecal administration of Shh. Basso, Beattie and Bresnahan (BBB) score, Gridwalk test and bodyweight were weekly assessed. Animals were sacrificed six weeks after SCI and immunohistological analyses were conducted. The results were compared between groups and statistical analysis was performed (p < 0.05 was considered significant). Results The intrathecal administration of Shh led to significantly increased polarization of macrophages toward the anti-inflammatory M2-phenotype, significantly decreased T-lymphocytic invasion and significantly reduced resident microglia six weeks after the injury. Reactive astrogliosis was also significantly reduced while changes in size of the posttraumatic cyst as well as the overall macrophagic infiltration, although reduced, remained insignificant. Finally, with the administration of Shh, gain of bodyweight (216.6 ± 3.65 g vs. 230.4 ± 5.477 g; p = 0.0111) and BBB score (8.2 ± 0.2 vs. 5.9 ± 0.7 points; p = 0.0365) were significantly improved compared to untreated animals six weeks after SCI as well. Conclusion Intrathecal Shh-administration showed neuroprotective effects with attenuated neuroinflammation, reduced astrogliosis and improved functional recovery six weeks after severe contusion/compression SCI.

Thoracic spinal cord injury without major bone injury associated with ossification of the ligamentum flavum

2019 ◽  
Vol 24 (1) ◽  
pp. 174-177 ◽  
Author(s):  
Masaaki Machino ◽  
Shiro Imagama ◽  
Keigo Ito ◽  
Kei Ando ◽  
Kazuyoshi Kobayashi ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Ligamentum Flavum ◽  
Thoracic Spinal Cord ◽  
Thoracic Spinal ◽  
Bone Injury ◽  
Cord Injury

Hyperbaric Oxygen Therapy After Acute Thoracic Spinal Cord Injury

Spine ◽  
2018 ◽  
Vol 43 (8) ◽  
pp. E442-E447 ◽  
Author(s):  
Asdrubal Falavigna ◽  
Manuela Peletti Figueiró ◽  
Pedro Guarise da Silva ◽  
Lucas Piccoli Conzatti ◽  
Elisa Braun Rizkalla ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Thoracic Spinal Cord ◽  
Thoracic Spinal ◽  
Cord Injury

Thoracic Spinal Cord Injury Without Radiographic Abnormality in a Skeletally Mature Patient

Spine ◽  
2003 ◽  
Vol 28 (4) ◽  
pp. E78-E80 ◽  
Author(s):  
S. R. Samsani ◽  
D. Calthorpe ◽  
G. Geutjens
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Thoracic Spinal Cord ◽  
Radiographic Abnormality ◽  
Thoracic Spinal ◽  
Cord Injury ◽  
Mature Patient

scholarly journals Bone Marrow-Derived Monocytes Drive the Inflammatory Microenvironment in Local and Remote Regions after Thoracic Spinal Cord Injury

2019 ◽  
Vol 36 (6) ◽  
pp. 937-949 ◽  
Author(s):  
Diana M. Norden ◽  
Timothy D. Faw ◽  
Daniel B. McKim ◽  
Rochelle J. Deibert ◽  
Lesley C. Fisher ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Bone Marrow ◽  
Spinal Cord Injury ◽  
Thoracic Spinal Cord ◽  
Inflammatory Microenvironment ◽  
Thoracic Spinal ◽  
Cord Injury

A Developmental Rehabilitation Robotic System for a Rat With Complete Thoracic Spinal Cord Injury in Quadruped Posture

2018 ◽  
Vol 3 (3) ◽  
pp. 2109-2115 ◽  
Author(s):  
Dollaporn Anopas ◽  
Sing Yian Chew ◽  
Junquan Lin ◽  
Seng Kwee Wee ◽  
Tow Peh Er ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Robotic System ◽  
Thoracic Spinal Cord ◽  
Thoracic Spinal ◽  
Cord Injury ◽  
Rehabilitation Robotic

scholarly journals Horizontal ladder task-specific re-training in adult rats with contusive thoracic spinal cord injury

2011 ◽  
Vol 29 (4) ◽  
pp. 275-286
Author(s):  
Stephen M. Onifer ◽  
Oliver Zhang ◽  
Laura K. Whitnel-Smith ◽  
Kashif Raza ◽  
Christopher R. O'Dell ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Adult Rats ◽  
Thoracic Spinal Cord ◽  
Thoracic Spinal ◽  
Cord Injury
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