Apoplexy in a Pituitary Chromophobe Adenoma Producing the Syndrome of Middle Cerebral Artery Thrombosis

1952 ◽  
Vol 9 (2) ◽  
pp. 210-213 ◽  
Author(s):  
Max T. Schnitker ◽  
Harley B. Lehnert
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Artery Thrombosis ◽  
Chromophobe Adenoma

scholarly journals Role of cyclic flow reductions in the guinea pig middle cerebral artery thrombosis model

1998 ◽  
Vol 76 ◽  
pp. 98
Author(s):  
Ken-ichi Kawano ◽  
Kazuo Umemura ◽  
Kazunao Kondo ◽  
Yasuhiko Ikeda ◽  
Yasuhiro Suzuki ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Cyclic Flow ◽  
Thrombosis Model ◽  
Artery Thrombosis

scholarly journals Role of thrombogenic factors on the middle cerebral artery thrombosis in guinea pigs

1997 ◽  
Vol 73 ◽  
pp. 125
Author(s):  
Kazuva Hokamura ◽  
Kazuo Umemura ◽  
Seiji Kaku ◽  
Kenichi Kawano ◽  
Mitsuyoshi Nakashima
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Guinea Pigs ◽  
Artery Thrombosis

scholarly journals Middle cerebral artery fenestration: Thromboembolic and hemorrhagic complications

2019 ◽  
Vol 25 (6) ◽  
pp. 644-647
Author(s):  
Mohamad Abdalkader ◽  
Christian Raftopoulos ◽  
Patrice Finet ◽  
Thanh N Nguyen ◽  
Pierre Goffette
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Arteriovenous Malformations ◽  
Cross Sectional ◽  
Vascular Abnormalities ◽  
Artery Thrombosis ◽  
Hemorrhagic Complications ◽  
Cross Sectional Imaging ◽  
Sectional Imaging

Cerebral artery fenestrations are rare anatomical variants usually detected incidentally on cross-sectional imaging or cerebral angiography. Although considered benign findings, many reports have described their association with vascular abnormalities such as aneurysms or arteriovenous malformations, and to a lesser extent with ischemic or hemorrhagic complications. We report a case of middle cerebral artery fenestration associated with subarachnoid hemorrhage and middle cerebral artery thrombosis. To our knowledge, there has been no prior report of middle cerebral artery fenestration with a similar presentation.

Effect of TTC-909 in a middle cerebral artery thrombosis model in stroke-prone spontaneously hypertensive rats

2002 ◽  
Vol 449 (1-2) ◽  
pp. 127-133 ◽  
Author(s):  
Yasuko Karasawa ◽  
Takehiko Hitomi ◽  
Hiroko Komiyama ◽  
Yoshihiko Isobe ◽  
Tsunefumi Kobayashi ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Spontaneously Hypertensive Rats ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive ◽  
Thrombosis Model ◽  
Artery Thrombosis

Evaluation of the disintegrin, triflavin, in a rat middle cerebral artery thrombosis model

1997 ◽  
Vol 321 (3) ◽  
pp. 301-305 ◽  
Author(s):  
Seiji Kaku ◽  
Kazuo Umemura ◽  
Atsuhiro Mizuno ◽  
Tomihisa Kawasaki ◽  
Mitsuyoshi Nakashima
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Thrombosis Model ◽  
Artery Thrombosis

scholarly journals A middle cerebral artery thrombosis model in squirrel monkeys induced by a photochemical reaction.

1996 ◽  
Vol 71 ◽  
pp. 321
Author(s):  
Seiji Kaku ◽  
Kazuo Umemura ◽  
Atsuhiro Mizuno ◽  
Kazunao Kondoh ◽  
Mitsuyoshi Nakashima
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Photochemical Reaction ◽  
Squirrel Monkeys ◽  
Thrombosis Model ◽  
Artery Thrombosis

Abstract P767: Understanding the Role of Microglial Il-1α After Stroke

Stroke ◽  
2021 ◽  
Vol 52 (Suppl_1) ◽  
Author(s):  
Eloise Lemarchand ◽  
Sarah Ma ◽  
Abir A Rahman ◽  
Amruta Narayanappa ◽  
Graham Coutts ◽  
...  
Keyword(s):  
Ischaemic Stroke ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Topical Application ◽  
Haemorrhagic Stroke ◽  
Sterile Inflammation ◽  
Group 4 ◽  
Artery Thrombosis

The role of inflammation driven by the pro-inflammatory cytokine interleukin-1 (IL-1) during poststroke injury has been the focus of intense research. Indeed, pre-clinical studies have demonstrated the deleterious actions of IL-1 after stroke, whilst blocking its actions is beneficial in pre-clinical and clinical settings. Whilst most studies have focused on the role of IL-1β, the role of IL-1α during poststroke inflammation has been largely overlooked and very little has been done to examine the selective contribution of each IL-1 isoform in ischaemic stroke. In this study, we have investigated the contribution of IL-1α to ischaemic and haemorrhagic stroke. Methods : in vivo model of middle cerebral artery thrombosis through topical application of FeCl3 (40%) (n=4/group (4, 24, 72h) histology, n=6 /group (4, 24, 72 ) qPCR) in vivo model of haemorrhagic stroke induced by using the collagenase model (intra-striatal injection of collagenase VII-S, 0.045U) (n=4/group (4, 24h) histology). We first investigated the spatio-temporal expression of IL-1 in the brain after ischaemic stroke using an in vivo model of middle cerebral artery thrombosis through topical application of FeCl3 (n=4-6/group). We observed IL-1α positive microglia as early as 4 hours after ischaemic stroke. At 24 hours we observed IL-1α and also IL-1β positive microglia, moreover, IL-1β was also expressed by neutrophils and monocytes. These results have been confirmed by qPCR. Interestingly, we observed similar results after haemorrhagic stroke, induced by using the collagenase model, whereby IL-1α expression in microglia precedes IL-1β expression (n=4/group). The early expression of IL-1α in microglia in both models suggest a critical role for the microglial response during sterile inflammation. To further investigate the role of microglial IL-1α, we have generated a conditional IL-1α mouse mutant crossed with CX3CR1 Cre-ERT2 mice to induce a specific deletion of IL-1α in microglia. Future experiments using this genetic model will clarify the role of IL-1α during the acute phase of strokes.

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