Systemic beta-interferon therapy for recurrent gliomas: a brief report

1989 ◽  
Vol 71 (5) ◽  
pp. 639-641 ◽  
Author(s):  
M. Stephen Mahaley ◽  
Edward J. Dropcho ◽  
Linda Bertsch ◽  
Tammy Tirey ◽  
G. Yancey Gillespie
Keyword(s):  
Interferon Therapy ◽  
Tumor Volume ◽  
Content Type ◽  
Recurrent Gliomas ◽  
Beta Interferon ◽  
Contrast Enhanced Ct ◽  
Contrast Enhanced ◽  
Enhanced Ct ◽  
Progression Of Disease ◽  
Fine Print

✓ Recombinant beta-interferon in escalating dosages was administered intravenously three times weekly to seven patients with recurrent gliomas. No evidence of response was seen in any patient, either on neurological examination or by computerized tomography (CT). However, stabilization of tumor volume, assessed from contrast-enhanced CT scans, occurred for 8 to 26 weeks in three patients. Immediate progression of disease despite treatment occurred in four patients.

The contrast-enhanced CT scan in the diagnosis of isodense subdural hematoma

1979 ◽  
Vol 50 (1) ◽  
pp. 64-69 ◽  
Author(s):  
Fong Y. Tsai ◽  
James E. Huprich ◽  
Hervey D. Segall ◽  
James S. Teal
Keyword(s):  
Cerebral Cortex ◽  
Ct Scan ◽  
Subdural Hematoma ◽  
Correct Diagnosis ◽  
Content Type ◽  
Subdural Hematomas ◽  
Contrast Enhanced Ct ◽  
Contrast Enhanced ◽  
Enhanced Ct ◽  
Fine Print

✓ The authors review 29 cases of surgically-proven isodense subdural hematomas examined by non-contrast and contrast-enhanced computerized tomography scans. Three types of isodense collections were noted: homogeneous isodense collections, mixed-density collections, and gravitational layering within subdural collections. Contrast enhancement within the cerebral cortex, cortical vessels, and subdural membranes led to the correct diagnosis in each case. Contrast-enhanced scans are essential for the evaluation of isodense subdural hematomas.

The pseudodelta sign in acute head trauma

1988 ◽  
Vol 69 (6) ◽  
pp. 867-868 ◽  
Author(s):  
Joel W. Yeakley ◽  
John S. Mayer ◽  
Larry L. Patchell ◽  
K. Francis Lee ◽  
Michael E. Miner
Keyword(s):  
Head Trauma ◽  
Superior Sagittal Sinus ◽  
Ct Scans ◽  
Content Type ◽  
Sagittal Sinus ◽  
Contrast Enhanced Ct ◽  
Contrast Enhanced ◽  
Enhanced Ct ◽  
Triangular Area ◽  
Fine Print

✓ The “delta sign” is a triangular area of high density with a low-density center seen on contrast-enhanced computerized tomography (CT) scans in the location of the superior sagittal sinus. It indicates thrombosis of the sinus. The authors describe the “pseudodelta sign,” which is similar but is seen on non-contrast-enhanced CT scans and which has a high correlation with hemorrhage secondary to acute head trauma.

Systemic gamma-interferon therapy for recurrent gliomas

1988 ◽  
Vol 69 (6) ◽  
pp. 826-829 ◽  
Author(s):  
M. Stephen Mahaley ◽  
Linda Bertsch ◽  
Sharon Cush ◽  
G. Yancey Gillespie
Keyword(s):  
Computerized Tomography ◽  
Interferon Therapy ◽  
Gamma Interferon ◽  
Disappointing Result ◽  
Content Type ◽  
Recurrent Gliomas ◽  
Enhanced Ct ◽  
Initial Tumor ◽  
Fine Print

✓ Recombinant gamma-interferon (2 mg/sq m) was administered intravenously twice weekly in 8-week courses to 14 patients with recurrent gliomas. Computerized tomography (CT) evidence of response was seen in only one patient, and stabilization for 12 to 86 weeks was recorded in three. This was a disappointing result, particularly in a series of patients with relatively small initial tumor volumes (less than 50 cu mm on enhanced CT) and Karnofsky functional ratings of 70 or higher. In addition, several instances of toxicity potentially attributable to gamma-interferon were observed.

scholarly journals NIMG-44. IMPACT OF DELAYED CONTRAST ENHANCED CT SCANS (CECT) ON GROSS TUMOR VOLUME (GTV) IN GLIOBLASTOMA (GBM)

2016 ◽  
Vol 18 (suppl_6) ◽  
pp. vi134-vi134
Author(s):  
Narendra Kumar ◽  
Kanchan K. Mukherjee ◽  
Sameer Vyas ◽  
Nikesh Hanumanthappa ◽  
Anindya Mukherjee ◽  
...  
Keyword(s):  
Gross Tumor Volume ◽  
Tumor Volume ◽  
Ct Scans ◽  
Contrast Enhanced Ct ◽  
Contrast Enhanced ◽  
Enhanced Ct

Subdural empyema: burr holes or craniotomy?

1993 ◽  
Vol 78 (4) ◽  
pp. 574-578 ◽  
Author(s):  
Arnold P. L. Bok ◽  
Jonathan C. Peter
Keyword(s):  
Subdural Empyema ◽  
Superficial Infection ◽  
Neck Stiffness ◽  
Content Type ◽  
Source Of Infection ◽  
Contrast Enhanced Ct ◽  
Contrast Enhanced ◽  
Enhanced Ct ◽  
Common Clinical Presentation ◽  
Burr Holes

✓ Ninety patients with subdural empyema were treated in the period after computerized tomography (CT) became available (1979 to 1991). Males predominated by a ratio of 2:1, and 40 patients were between 11 and 20 years old. The site of origin was the paranasal air sinuses in 53 patients, the middle ear in 19, and a superficial infection in eight; the source of infection was not known in 10. The most common clinical presentation was headache, fever, neck stiffness, seizures, or periorbital swelling; only seven patients had status epilepticus. While the erythrocyte sedimentation rate and white blood cell count were invariably elevated, the cerebrospinal fluid showed nonspecific pleocytosis in the 60 patients who underwent lumbar puncture. The definitive preoperative diagnosis was made by contrast-enhanced CT in all cases. Surgical treatment was by multiple burr holes in 37 patients, burr holes and small craniectomies in 33, burr holes with catheter drainage in seven, and a large craniotomy in 12. One patient was treated without surgery. The mortality rate was 7.7%, with 86% making a good recovery. These results compare favorably with those reported in other studies using craniotomy alone, and suggest that burr holes should not be disregarded as a method of treating subdural empyema where contrast-enhanced CT facilities are available.

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