Pigmented villonodular synovitis of the spine

1993 ◽  
Vol 79 (3) ◽  
pp. 456-459 ◽  
Author(s):  
Leo J. P. Clark ◽  
Patrick W. McCormick ◽  
Don R. Domenico ◽  
Lucy Savory

✓ Pigmented villonodular synovitis commonly occurs in synovial joints of the appendicular skeleton, but rarely affects the synovial joints of the spine. It has both neoplastic and benign features, and the etiology is thought to be posttraumatic. The case of a young man presenting with paraparesis and a large thoracic lesion is reported.

2007 ◽  
Vol 7 (2) ◽  
pp. 248-253 ◽  
Author(s):  
Michael A. Finn ◽  
Todd D. McCall ◽  
Meic H. Schmidt

✓Pigmented villonodular synovitis (PVNS) is a proliferative disorder of the synovium with a predisposition for the appendicular skeleton. Rarely PVNS can arise from the spine, where this disorder usually presents with localized or radicular pain secondary to involvement of the posterior elements. The authors report the case of an 82-year-old woman who presented with long-standing neck pain and acute upper-extremity numbness and weakness. Computed tomography imaging revealed a mixed sclerotic and lucent lesion affecting the dens and right lateral mass of C-2. There was also a pathological fracture at the base of the dens with 8 mm of anterior dens displacement. Magnetic resonance imaging demonstrated a diffusely infiltrative process that was nonenhancing. Because of instability, the patient underwent transarticular screw fixation, and a biopsy of the lesion was also performed at this time. Histopathological analysis was consistent with a diagnosis of PVNS. To the authors' knowledge, this is the first report of PVNS involving the C-2 vertebra or causing a pathological fracture.


1996 ◽  
Vol 84 (4) ◽  
pp. 592-597 ◽  
Author(s):  
Caterina Giannini ◽  
Bernd W. Scheithauer ◽  
Doris E. Wenger ◽  
Krishnan K. Unni

✓ Cases of pigmented villonodular synovitis (PVNS) that affect the axial skeleton are rare and thus information regarding its natural history, treatment, and prognosis remains limited. To characterize this lesion more fully, the authors reviewed their experience with 12 cases of PVNS of the spine (one of which had been previously reported), then reviewed the 11 cases that previously had been reported, and obtained additional follow-up data in six of them. On the basis of the cumulative data provided by these 22 cases, PVNS of the spine appears to occur over a wide range of ages (21–81 years) and, contrary to what was previously suggested, does not show definite gender predilection (12 women and 10 men). The lesion affects the posterior elements of the vertebrae at all levels and involves the facet joints in 89% of cases. Extension into the epidural spine is frequent (70%). Surgical resection appears to be the treatment of choice. Although PVNS of the spine tends to recur locally (18%), repeat surgical excision appears to be curative.


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