Marked reduction of cerebral vasospasm with lumbar drainage of cerebrospinal fluid after subarachnoid hemorrhage

2004 ◽  
Vol 100 (2) ◽  
pp. 215-224 ◽  
Author(s):  
Paul Klimo ◽  
John R. W. Kestle ◽  
Joel D. MacDonald ◽  
Richard H. Schmidt
Keyword(s):  
Cerebrospinal Fluid ◽  
Subarachnoid Hemorrhage ◽  
Cerebral Vasospasm ◽  
Marked Reduction ◽  
Lumbar Drainage

Proteomic Biomarker Discovery in Cerebrospinal Fluid for Cerebral Vasospasm Following Subarachnoid Hemorrhage

2012 ◽  
Vol 21 (1) ◽  
pp. 30-41 ◽  
Author(s):  
Shivanand P. Lad ◽  
Harald Hegen ◽  
Gaurav Gupta ◽  
Florian Deisenhammer ◽  
Gary K. Steinberg
Keyword(s):  
Cerebrospinal Fluid ◽  
Subarachnoid Hemorrhage ◽  
Cerebral Vasospasm ◽  
Biomarker Discovery

Endothelin-1 levels in plasma and cerebrospinal fluid of patients with cerebral vasospasm after aneurysmal subarachnoid hemorrhage

2005 ◽  
Vol 64 ◽  
pp. S2-S5 ◽  
Author(s):  
Iruena Moraes Kessler ◽  
Yolanda Galindo Pacheco ◽  
Silene Paulino Lozzi ◽  
Antônio Santos de Araújo ◽  
Franz Jooji Onishi ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Subarachnoid Hemorrhage ◽  
Cerebral Vasospasm ◽  
Aneurysmal Subarachnoid Hemorrhage ◽  
Endothelin 1

scholarly journals Endothelin-1 concentration increases in the cerebrospinal fluid in cerebral vasospasm caused by subarachnoid hemorrhage

2000 ◽  
Vol 53 (2) ◽  
pp. 131-135 ◽  
Author(s):  
Kensuke Suzuki ◽  
Kotoo Meguro ◽  
Takeshi Sakurai ◽  
Yoshifumi Saitoh ◽  
Sadayuki Takeuchi ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Subarachnoid Hemorrhage ◽  
Cerebral Vasospasm ◽  
Endothelin 1

RELATION BETWEEN CHANGE IN Ca AND Mg LEVELS OF CEREBROSPINAL FLUID AFTER SUBARACHNOID HEMORRHAGE AND THE OCCURRENCE OF VASOSPASM

1998 ◽  
Vol 08 (04) ◽  
pp. 275-282 ◽  
Author(s):  
N. SATO ◽  
K. KURODA ◽  
M. SUZUKI ◽  
A. OGAWA ◽  
K. SERA
Keyword(s):  
Cerebrospinal Fluid ◽  
Trace Elements ◽  
Subarachnoid Hemorrhage ◽  
Muscle Contraction ◽  
Cerebral Vasospasm ◽  
Principal Mechanism ◽  
Cisternal Drainage ◽  
Patient’S Outcome ◽  
Sampling Times

Cerebral vasospasm is a characteristic complication after subarachnoid hemorrhage (SAH), and the onset of vasospasm is a very important factor to decide the patient's outcome. Though various causal factors have been proposed for cerebral vasospasm after SAH, none of them explain the whole pathomechanism of vasospasm. To evaluate the role of trace elements in vasospasm, we have examined the sequential change in element concentration in the cerebrospinal fluid (CSF) after SAH by PIXE, and have investigated the relation between trace elements and vasospasm. We obtained the CSF samples from cisternal drainage of 17 patients with SAH who underwent radical surgery within 48 hours from the onset. The drainage was placed into basal cisterns at the end of the operation. Three sampling times (3-5, 7-9 and 12-14 days from the onset) were scheduled, because vasospasm is likely to occur from day 4 through day 14 after the onset. Cerebral angiograms were performed to classify vasospasm on day 1 and 7 after the onset. We measured 29 elements in the CSF and focused on Ca and Mg levels in this study, since Ca -influx into the smooth muscle cells is a principal mechanism of muscle contraction, and the competition between Ca and Mg is closely related to the muscle contraction. We found a significantly lower levels of Mg in the CSF of patients with vasospasm on days 7-9 after the onset. These results suggest that Mg in the CSF possibly ameliorate vasoconstriction due to Ca in the pathomechanism of vasospasm.

Phosphoramidon prevents cerebral vasospasm following subarachnoid hemorrhage in dogs: The relationship to endothelin-1 levels in the cerebrospinal fluid

Life Sciences ◽  
1991 ◽  
Vol 49 (11) ◽  
pp. 841-848 ◽  
Author(s):  
Yasuo Matsumura ◽  
Ruriko Ikegawa ◽  
Yasunori Suzuki ◽  
Masanori Takaoka ◽  
Takeshi Uchida ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Subarachnoid Hemorrhage ◽  
Cerebral Vasospasm ◽  
Endothelin 1 ◽  
The Relationship

Cerebrospinal Fluid Tenascin-C in Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage

2011 ◽  
Vol 23 (4) ◽  
pp. 310-317 ◽  
Author(s):  
Hidenori Suzuki ◽  
Kenji Kanamaru ◽  
Masato Shiba ◽  
Masashi Fujimoto ◽  
Kyoko Imanaka-Yoshida ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Subarachnoid Hemorrhage ◽  
Cerebral Vasospasm ◽  
Aneurysmal Subarachnoid Hemorrhage ◽  
Tenascin C
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