Asymptomatic spherocytosis presenting with spinal cord compression

2005 ◽  
Vol 2 (4) ◽  
pp. 491-494 ◽  
Author(s):  
Florian Jalbert ◽  
Patrick Chaynes ◽  
Jacques Lagarrigue
Keyword(s):  
Spinal Cord ◽  
Mr Imaging ◽  
Spinal Cord Compression ◽  
Extramedullary Hematopoiesis ◽  
Cord Compression ◽  
Compensatory Mechanism ◽  
Imaging Features ◽  
Chronic Anemia ◽  
Content Type ◽  
History Of

✓ Extramedullary hematopoiesis (EMH) is a compensatory mechanism occurring in patients with chronic anemia, which occurs most frequently with thalassemia. The authors report the case of a 57-year-old man, with no history of clinical or hematological disease, presenting with spinal cord compression. Magnetic resonance (MR) imaging demonstrated a homogeneous posterior epidural mass extending from T-3 to T-6. Following decompressive surgery, the patient's symptoms improved. Histological analysis showed features consistent with a diagnosis of EMH. Subsequent workup was remarkable for an asymptomatic spherocytosis without anemia. There was no family history of anemia. An EMH-related presentation of mild spherocytosis has been described in the literature, but its epidural location led to spinal cord compression. The MR imaging features were suggestive of EMH, but in the presence of spinal cord compression and in the absence of a history of chronic anemia, the authors did not believe that nonsurgical management would have been reasonable.

Segmental neurofibromatosis—induced spinal cord compression

2001 ◽  
Vol 95 (2) ◽  
pp. 236-238
Author(s):  
Natarajan Muthukumar
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Peripheral Nerves ◽  
Cord Compression ◽  
Lower Extremity Weakness ◽  
Content Type ◽  
Neuralgic Pain ◽  
History Of ◽  
Intercostal Neuralgia ◽  
The Right

✓ Spinal segmental neurofibromatosis (NF) is a rare entity. To date, patients in reported cases of segmental NF (or NF5) have harbored neurofibromas involving the peripheral nerves only. The author reports a rare case of segmental NF that caused spinal cord compression in a 40-year-old woman who presented with a 6-month history of intercostal neuralgia. Examination revealed mild lower-extremity weakness and dysesthesia in the right-sided T-9 dermatome. Magnetic resonance imaging revealed three neurofibromas involving the T-9 region, which were excised, and the patient's neuralgic pain was resolved postoperatively. Traditionally, it has been believed that segmental NF involved only the peripheral nerves. The present case illustrates that although rare, spinal cord compression can also occur in patients with segmental NF.

A novel dynamic model for experimental spinal cord compression

2005 ◽  
Vol 2 (4) ◽  
pp. 466-471 ◽  
Author(s):  
Gerhard Marquardt ◽  
Matthias Setzer ◽  
Alf Theisen ◽  
Edgar Dettmann ◽  
Volker Seifert
Keyword(s):  
Spinal Cord ◽  
Mr Imaging ◽  
Dynamic Model ◽  
Dura Mater ◽  
Spinal Cord Compression ◽  
Cord Compression ◽  
Neurological Deficits ◽  
Content Type ◽  
Interlaminar Approach ◽  
Fine Print

Object. The goal of this study was to develop a novel dynamic model for experimental spinal cord compression that closely approximates neoplastic epidural compression of the spinal cord in humans. Methods. In 30 New Zealand white rabbits, the thoracic spine was exposed via a posterior approach. On each side of one vertebral lamina a small hole was drilled caudal to the articular process. A silicone band was passed through these holes, forming a loop. The spinal dura mater was exposed via an interlaminar approach. The loop was brought into contact with the dura mater and fixed in its position encircling 270° of the circumference of the spinal cord. Thereafter, the loop was gradually tightened at set times by pulling at the ends of the band and fixing them again in their new position. The spinal cord was thus increasingly compressed in a circular and dynamic manner. Neurological deficits of various degrees were created in all animals in the compression group, and the compressive effect of the loop was reliably demonstrated on MR imaging. After decompression of the spinal cord, the neurological deficits were reversible in the majority of animals, and MR imaging revealed either no signal changes or only circumscribed ones within the cord. In contrast, MR images obtained in animals that did not recover revealed the occurrence of extensive chronic myelopathy. Conclusions. This novel model features reproducibility of paresis and neurological recovery. It is a dynamic model simulating circular tumor growth and is characterized by its easy, straightforward, and cost-saving applicability.

Paraspinal myxoma with spinal cord compression

1981 ◽  
Vol 54 (4) ◽  
pp. 542-544 ◽  
Author(s):  
Ali Tahmouresie ◽  
Peter M. Farmer ◽  
Norman Stokes
Keyword(s):  
Spinal Cord ◽  
Back Pain ◽  
Spinal Cord Compression ◽  
Marked Improvement ◽  
Cord Compression ◽  
Paraspinal Muscle ◽  
Content Type ◽  
History Of ◽  
Fine Print

✓ A patient with thoracolumbar paraspinal muscle myxoma with spinal cord compression presented with a long history of back pain and recent paraparesis. Removal of the tumor and decompression of the spinal cord provided marked improvement of the weakness.

Spinal cord compression due to prolapse of cervical intervertebral disc (herniation of nucleus pulposus)

1983 ◽  
Vol 59 (5) ◽  
pp. 847-853 ◽  
Author(s):  
Sean A. O'Laoire ◽  
David G. T. Thomas
Keyword(s):  
Spinal Cord ◽  
Nucleus Pulposus ◽  
Spinal Cord Compression ◽  
Cord Compression ◽  
Cervical Disc ◽  
Intervertebral Disc Herniation ◽  
Disc Prolapse ◽  
Content Type ◽  
History Of ◽  
High Cervical

✓ Twenty-six patients who presented with spinal cord compression due to cervical disc prolapse (herniation of the nucleus pulposus) were treated by anterior discectomy. There was a high incidence of disc prolapse at the C3–4 level. The most severe degrees of preoperative disability were associated with prolapse at that level. Impairment of posterior column function, particularly in the upper limbs, played a major part in producing disability. High cervical disc prolapse can produce a clinical picture that is predominantly like that of a posterior cord syndrome. Preexisting fusion of vertebral bodies in the cervical spine and a history of cervical spinal trauma appear to be predisposing factors. Discectomy is an effective treatment of this condition. Spinal cord compression due to cervical disc prolapse should be distinguished from spondylotic myelopathy.

Nonsurgical approach to paraparesis due to extramedullary hematopoiesis

1995 ◽  
Vol 82 (4) ◽  
pp. 657-660 ◽  
Author(s):  
Khosrov Parsa ◽  
Ahmad Oreizy
Keyword(s):  
Spinal Cord ◽  
Radiation Therapy ◽  
Spinal Cord Compression ◽  
Extramedullary Hematopoiesis ◽  
Cord Compression ◽  
The Other ◽  
Blood Transfusions ◽  
Therapeutic Tool ◽  
Content Type ◽  
Fine Print

✓ Two cases of spinal cord compression due to extradural extramedullary hematopoiesis are reported and the non-surgical means used for their diagnosis and treatment are presented. One patient was treated with blood transfusions and radiation therapy, the other with blood transfusions alone. Both patients have made almost complete clinical recoveries from spinal cord compression. A mechanism is proposed to explain how blood transfusions can serve as an important diagnostic, as well as a therapeutic, tool in the management of this entity.

Progressive paraparesis due to thoracic extramedullary hematopoiesis in myelofibrosis

1993 ◽  
Vol 79 (1) ◽  
pp. 125-127 ◽  
Author(s):  
Nina De Klippel ◽  
Marie F. Dehou ◽  
Claire Bourgain ◽  
Rik Schots ◽  
Jaques De Keyser ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Extramedullary Hematopoiesis ◽  
Cord Compression ◽  
Hematopoietic Tissue ◽  
Content Type ◽  
Radiotherapy Alone ◽  
Progressive Paraparesis ◽  
Fine Print

✓ A patient with myelofibrosis who developed a progressive paraparesis caused by spinal cord compression due to thoracic extramedullary hematopoietic tissue is reported. He recovered well after local radiotherapy alone.

Spinal cord compression due to extramedullary hematopoiesis in beta-thalassemia

2020 ◽  
Vol 78 (10) ◽  
pp. 663-664
Author(s):  
Renan Ramon Souza LOPES ◽  
Larissa Soares CARDOSO ◽  
Franz ONISHI
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Extramedullary Hematopoiesis ◽  
Cord Compression ◽  
Beta Thalassemia

Spinal cord compression by extramedullary hemopoietic tissue in sickle cell anemia

1975 ◽  
Vol 43 (4) ◽  
pp. 483-485 ◽  
Author(s):  
Abdel A. Ammoumi ◽  
Joanna H. Sher ◽  
Daniel Schmelka
Keyword(s):  
Spinal Cord ◽  
Sickle Cell ◽  
Spinal Cord Compression ◽  
Sickle Cell Anemia ◽  
Cord Compression ◽  
Content Type ◽  
Hemopoietic Tissue ◽  
Fine Print ◽  
Mass Recovery

✓ The authors report a patient with sickle cell anemia who suffered from paraplegia of 18 months duration due to spinal cord compression by a hemopoietic mass. Recovery following removal of the mass was complete.

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