Протеиназы с желатиназной активностью и их участие в регенерации амбулакра у голотурий Eupentacta fraudatrix (D’yakonov & Baranova, 1958) и Cucumaria japonica (Semper, 1868) (Echinodermata: Holothuroidea)

2020 ◽  
Vol 46 (6) ◽  
pp. 410-419
Author(s):  
А. П. Шульга ◽  
Н. Е. Ламаш
1992 ◽  
Vol 28 (5) ◽  
pp. 520-521 ◽  
Author(s):  
O. A. Drozdova ◽  
S. A. Avilov ◽  
A. I. Kalinovskii ◽  
V. A. Stonik

Steroids ◽  
1993 ◽  
Vol 58 (11) ◽  
pp. 508-517 ◽  
Author(s):  
Tatyana N. Makarieva ◽  
Valentin A. Stonik ◽  
Irina I. Kapustina ◽  
Valentin M. Boguslavsky ◽  
Andrei S. Dmitrenoik ◽  
...  

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Alexey V. Boyko ◽  
Alexander S. Girich ◽  
Ekaterina S. Tkacheva ◽  
Igor Yu. Dolmatov

2012 ◽  
Vol 7 (9) ◽  
pp. 1934578X1200700 ◽  
Author(s):  
Alexandra S. Silchenko ◽  
Anatoly I. Kalinovsky ◽  
Sergey A. Avilov ◽  
Pelageya V. Andryjaschenko ◽  
Pavel S. Dmitrenok ◽  
...  

Two new minor triterpene glycosides, cucumariosides B1 (1) and B2 (2) have been isolated from the Far Eastern sea cucumber Eupentacta fraudatrix. Structures of the glycosides were elucidated by 2D NMR spectroscopy and MS. Glycosides 1 and 2 belong to the cucumariosides B group and have unprecedented trisaccharide carbohydrate moieties without sulfate groups. Glycosides 1 and 2 differ from each other in side chain structures in the aglycone moieties. These minor substances are probably intermediate metabolites in the biosynthesis of triterpene pentaosides. Cytotoxic activities of glycosides 1 and 2 against mouse spleen lymphocytes and the cells of the ascite form of mouse Ehrlich carcinoma were studied, along with hemolytic activity against mouse erythrocytes and antifungal activity. Cucumarioside B1 (1) was not active in any of the tests, while cucumarioside B2 (2) demonstrated moderate hemolytic activity and low cytotoxic action against Ehrlich carcinoma cells.


2015 ◽  
Vol 10 (6) ◽  
pp. 1934578X1501000 ◽  
Author(s):  
Alexandra S. Silchenko ◽  
Anatoly I. Kalinovsky ◽  
Pavel S. Dmitrenok ◽  
Vladimir I. Kalinin ◽  
Andrey N. Mazeika ◽  
...  

New minor triterpene glycoside, cucumarioside E (1) has been isolated from the Far Eastern sea cucumber Cucumaria japonica. The structure of the glycoside was elucidated by 2D-NMR specroscopy and mass-spectrometry. The glycoside has glucose instead of quinovose as the second monosaccharide residue and xylose as third monosaccharide residue that is unique structural feature for triterpene glycosides carbohydrate chains from sea cucumbers belonging to the genus Cucumaria.


2007 ◽  
Vol 2 (9) ◽  
pp. 1934578X0700200
Author(s):  
Viatcheslav Rybin ◽  
Konstantin Pavel ◽  
Dmitry Mitrofanov

1- O-Alkylglycerol ether lipids were investigated in two holothurian species, Cucumaria japonica and C. okhotensis. Species specific differences in the content of 1- O-alkylglycerol ether lipids were found. Some alkyl radicals of the 1- O-alkylglycerol ether lipid molecules contained branched hydrocarbon chains. The ratio between the content of linear and branched saturated 1- O-alkylglycerol ether lipids was 1.53 in C. okhotensis and 0.55 in C. japonica.


2013 ◽  
Vol 8 (8) ◽  
pp. 1934578X1300800 ◽  
Author(s):  
Alexandra S. Silchenko ◽  
Anatoly I. Kalinovsky ◽  
Sergey A. Avilov ◽  
Pelageya V. Andryjaschenko ◽  
Pavel S. Dmitrenok ◽  
...  

Three new minor triterpene glycosides, cucumariosides I1 (1), I3 (2) and I4 (3) have been isolated from the Far Eastern sea cucumber Eupentacta fraudatrix. Structures of the glycosides were elucidated by 2D NMR spectroscopy and MS. Glycosides 1–3 belong to the group of cucumariosides I, having branched pentasaccharide carbohydrate moieties with two sulfate groups and possessing 3- O-methyl-D-xylose as a terminal monosaccharide unit that is a characteristic feature of all the glycosides isolated from E. fraudatrix. Glycosides 1 and 2 differ from each other by the side chain structures in the holostane aglycone moieties, while cucumarioside I4 (3) has a 23,24,25,26,27-pentanorlanostane aglycone with an 18(16)-lactone. Cytotoxic activities of glycosides 1–3 against mouse spleen lymphocytes and ascite form of mouse Ehrlich carcinoma cells, along with hemolytic activity against mouse erythrocytes and antifungal activity were studied. Glycoside 1, having an aglycone side chain with a 24(25)-double bond, possesses moderate activity in all the tests, while glycoside 2, having 23(24)-double bond and 25-hydroxy group in the side chain, and glycoside 3 with an aglycone with an 18(16)-lactone and shortened side chain have either low activity or are non-active.


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