scholarly journals Autoimmune biliary diseases: primary biliary cholangitis and primary sclerosing cholangitis

Pathologica ◽  
2021 ◽  
Vol 113 (03) ◽  
pp. 170-184
Author(s):  
Samantha Sarcognato ◽  
Diana Sacchi ◽  
Federica Grillo ◽  
Nora Cazzagon ◽  
Luca Fabris ◽  
...  
Keyword(s):  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Primary Biliary Cholangitis ◽  
Biliary Diseases

Cholestatic Liver Injury: Care of Patients With Primary Biliary Cholangitis or Primary Sclerosing Cholangitis

2016 ◽  
Vol 27 (4) ◽  
pp. 441-452 ◽  
Author(s):  
Laurie Larson ◽  
Michelle James ◽  
Andrea Gossard
Keyword(s):  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Disease Recurrence ◽  
Outpatient Setting ◽  
Primary Biliary Cholangitis ◽  
Malignant Neoplasms ◽  
Cholestatic Liver Disease ◽  
Gallbladder Polyps ◽  
Increased Risk ◽  
Common Causes

The most common causes of chronic cholestatic liver disease are primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC). Both disease processes are characterized by a destruction of intrahepatic and/or extrahepatic biliary ducts. The etiology is not entirely clear; however, there is an underlying autoimmune component contributing to both disease processes. Although PBC and PSC are often diagnosed and managed in the outpatient setting, in some instances, a patient may have jaundice, fatigue, and pruritus requiring evaluation and determination of the cholestatic cause. Patients with PSC should be monitored for evidence of cholangiocarcinoma, colon cancer, and gallbladder polyps as they are at an increased risk of malignant neoplasms. Liver transplant has the potential for improving quality of life, although disease recurrence is a risk.

Primary biliary cholangitis–primary sclerosing cholangitis in an evolving overlap syndrome: A case report

2017 ◽  
Vol 40 (10) ◽  
pp. 669-671 ◽  
Author(s):  
Daniele Mandolesi ◽  
Marco Lenzi ◽  
Antonietta D’Errico ◽  
Davide Festi ◽  
Franco Bazzoli ◽  
...  
Keyword(s):  
Case Report ◽  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Overlap Syndrome ◽  
Primary Biliary Cholangitis
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