scholarly journals Desmoplastic Small Round Cell Tumour (DSRCT) - A Case Report and Review of Literature

2014 ◽  
Vol 2 (2) ◽  
pp. 79-82
Author(s):  
AKM Amirul Morshed ◽  
Farhana Afroz ◽  
Chowdhury Md. Fuad Galib ◽  
Shahnoor Islam ◽  
Kaniz Hasina ◽  
...  
Keyword(s):  
Unusual Case ◽  
Round Cell ◽  
Review Of Literature ◽  
Lower Abdomen ◽  
Small Round Cell ◽  
Undifferentiated Cells ◽  
Characteristic Features ◽  
Immunohistochemical Evidence ◽  
High Level ◽  
Small Round Cell Tumour

Desmoplastic small round cell tumor (DSRCT) is a rare pathologic entity that most frequently affects the peritoneal cavity and presents in pediatric and adolescent boys. It often presents at an advanced stage and has a generally poor prognosis. Sometimes it may involve liver at diagnosis. We present an unusual case of DSRCT who was present with mass in lower abdomen, pain, hepatomegaly and mild ascites. This tumor is characterized by nests of small undifferentiated cells that show immunohistochemical evidence of epithelial, mesenchymal and neural differentiation. In our patient histologicaly tumor had the characteristic features of DSRCT and were composed of small round cells with hyperchromatic nuclei and scanty cytoplasm. With various difficulties in diagnosis we ultimately reached at diagnosis by open biopsy and immunohistochemistry. Now patient is on multidrug chemotherapy (modified p6 protocol). Diagnosis and management of a rare tumor needs high level of suspicion and in time intervention.DOI: http://dx.doi.org/10.3329/jpsb.v2i2.19552

scholarly journals Lymphoma Maxilla mimicking orbital cellulitis; case report and review of Literature

2018 ◽  
Vol 9 (2) ◽  
pp. 180-186 ◽  
Author(s):  
Shankar P. Shah ◽  
S. T. Chetri ◽  
Poonam Paudyal ◽  
P. Lavaju ◽  
B P Sah ◽  
...  
Keyword(s):  
Nasal Cavity ◽  
Orbital Cellulitis ◽  
Round Cell ◽  
Review Of Literature ◽  
Small Round Cell ◽  
Total Maxillectomy ◽  
Intravenous Antibiotics ◽  
Adjacent Structures ◽  
Small Round Cell Tumour

Background: Sinonasal lymphomas are the commonest nonepithelial malignancies of the nasal cavity and paranasal sinuses. They may spread from their site of origin in nasal cavity and invade adjacent structures including orbits leading to varying presentation and a diagnostic dilemma.Case: A-77- year old Nepalese male presented with swelling of left eye since 1 month and pain in the same eye since 2 days. Observation: Examination revealed axial proptosis, swelling of lids, restricted extraocular movement, diffuse conjunctival and ciliary congestion with chemosis. Visual acuity was grossly decreased. The case was diagnosed as left orbital cellulitis and treated with broad spectrum intravenous antibiotics and oral steriods. There was no response despite 3 days of antibiotics and steroids therefore a computed tomography was planned which showed features of Sinonasal malignancy invading the orbit. Repeated biopsy was suggestive of malignant small round cell tumour. In the view of unclear preoperative biopsy indicating further details on the histologic type of tumor and extensive erosion of maxilla with complete loss of vision in the eye the patient was planned for Total Maxillectomy with Orbital extenteration of the left orbit. Post-operative histopathological and Immunohistochemical report were suggestive of High grade Lymphoma. The patient was advised for Adjuvant Chemotherapy and Radiotherapy, which the patient refused due to financial constraints. He is on occasional follow up since the last 6 months.Conclusions: The diagnosis of maxillary sinus lymphoma needs to be borne in mind when a clinician encounters a case of Orbital Cellulitis. It may be difficult to diagnose clinically and require radio-pathological correlation.

Desmoplastic small round cell tumour: A review of literature and treatment options

2008 ◽  
Vol 17 (2) ◽  
pp. 107-112 ◽  
Author(s):  
C.E. Stuart-Buttle ◽  
C.J. Smart ◽  
S. Pritchard ◽  
D. Martin ◽  
I.M. Welch
Keyword(s):  
Treatment Options ◽  
Cell Tumour ◽  
Round Cell ◽  
Review Of Literature ◽  
Small Round Cell ◽  
Round Cell Tumour ◽  
Small Round Cell Tumour

Characteristic imaging features of desmoplastic small round cell tumour

2012 ◽  
Vol 43 (1) ◽  
pp. 93-102 ◽  
Author(s):  
Vandan Caur Arora ◽  
Anita P. Price ◽  
Stephen Fleming ◽  
Michael J. Sohn ◽  
Heather Magnan ◽  
...  
Keyword(s):  
Cell Tumour ◽  
Imaging Features ◽  
Round Cell ◽  
Small Round Cell ◽  
Characteristic Imaging ◽  
Round Cell Tumour ◽  
Small Round Cell Tumour

Desmoplastic small round cell tumour of the pleura: a case report with unusual follow-up

Lung Cancer ◽  
2002 ◽  
Vol 36 (3) ◽  
pp. 333-336 ◽  
Author(s):  
Gyula Ostoros ◽  
Zsolt Orosz ◽  
Gábor Kovács ◽  
Ilona Soltész
Keyword(s):  
Case Report ◽  
Cell Tumour ◽  
Round Cell ◽  
Small Round Cell ◽  
Round Cell Tumour ◽  
Small Round Cell Tumour

Desmoplastic small round cell tumour of the pleura: A case with unusual follow up

Lung Cancer ◽  
2000 ◽  
Vol 29 (1) ◽  
pp. 81
Author(s):  
Gy Ostoros ◽  
Zs Orosz ◽  
G Kovács ◽  
I Soltész
Keyword(s):  
Cell Tumour ◽  
Round Cell ◽  
Small Round Cell ◽  
Round Cell Tumour ◽  
Small Round Cell Tumour

A new case of scrotal localization of “small round cell tumour”

1995 ◽  
Vol 62 (1_suppl) ◽  
pp. 197-198
Author(s):  
N. Drei ◽  
M.C. Camuffo ◽  
R. Bertoldin ◽  
G. D'incà ◽  
E. Macri ◽  
...  
Keyword(s):  
Cell Tumour ◽  
Round Cell ◽  
Small Round Cell ◽  
Round Cell Tumour ◽  
Small Round Cell Tumour

— We present a case of scrotal localization of “small round cell tumour”. The patient, a 28-year-old man, underwent orchifunicolectomy and antiblastic chemotherapy (platinum, adriamycin, cyclophosphamide) and died after 13 months.

Intraabdominal desmoplastic small round cell tumour

2005 ◽  
Vol 21 (4) ◽  
pp. 279-281 ◽  
Author(s):  
L. Mingo ◽  
F. Seguel ◽  
V. Roll�n
Keyword(s):  
Cell Tumour ◽  
Round Cell ◽  
Small Round Cell ◽  
Round Cell Tumour ◽  
Small Round Cell Tumour

Intramedullary Ewing sarcoma of the spinal cord: consequences of molecular diagnostics

2001 ◽  
Vol 95 (2) ◽  
pp. 270-275 ◽  
Author(s):  
Robert J. Weil ◽  
Zhengping Zhuang ◽  
Svetlana Pack ◽  
Shimareet Kumar ◽  
Lee Helman ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Ewing Sarcoma ◽  
Unusual Case ◽  
Modern Medicine ◽  
Round Cell ◽  
Intramedullary Spinal Cord ◽  
Content Type ◽  
Small Round Cell ◽  
Neuroectodermal Tumors ◽  
Round Cell Tumors

✓ Molecular biological techniques have begun to transform modern medicine. These techniques have shown promise in the pathological diagnosis of difficult or uncommon tumors. Accurate molecular diagnosis of the small round-cell tumors, for example, is especially important because divergent therapies may be required to eradicate such disparate lesions as neuroblastoma, lymphoma, rhabdomyosarcoma, central primitive neuroectodermal tumors/medulloblastoma, or Ewing sarcoma (ES). The authors present an unusual case of a primary, extraosseous ES arising from the intramedullary spinal cord, in which molecular studies were required for specific diagnosis and therapeutic guidance.

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