Macular Hole Following Intravitreal Ranibizumab Injections for Choroidal Neovascularization

2010 ◽  
Vol 51 (5) ◽  
pp. 774 ◽  
Author(s):  
Young Joon Jo ◽  
Kyoung Nam Kim ◽  
Jong Eun Lee ◽  
Jung Yeul Kim
Keyword(s):  
Macular Hole ◽  
Choroidal Neovascularization ◽  
Intravitreal Ranibizumab

scholarly journals Management of Uveitis-Related Choroidal Neovascularization: From the Pathogenesis to the Therapy

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Enzo D’Ambrosio ◽  
Paolo Tortorella ◽  
Ludovico Iannetti
Keyword(s):  
Choroidal Neovascularization ◽  
Intravitreal Bevacizumab ◽  
Posterior Uveitis ◽  
Age Related Macular Degeneration ◽  
Vascular Endothelial ◽  
Intravitreal Ranibizumab ◽  
Serpiginous Choroiditis ◽  
Age Related ◽  
Stromal Cell Derived Factor ◽  
Endothelial Growth Factor

Inflammatory choroidal neovascularization is a severe but uncommon complication of uveitis, more frequent in posterior uveitis such as punctate inner choroidopathy, multifocal choroiditis, serpiginous choroiditis, and Vogt-Koyanagi-Harada syndrome. Its pathogenesis is supposed to be similar to the wet age related macular degeneration: hypoxia, release of vascular endothelial growth factor, stromal cell derived factor 1-alpha, and other mediators seem to be involved in the uveitis-related choroidal neovascularization. A review on the factors implicated so far in the pathogenesis of inflammatory choroidal neovascularization was performed. Also we reported the success rate of single studies concerning the therapies of choroidal neovascularization secondary to uveitis during the last decade: photodynamic therapy, intravitreal bevacizumab, and intravitreal ranibizumab, besides steroidal and immunosuppressive therapy. Hereby a standardization of the therapeutic approach is proposed.

scholarly journals A 5-Year-Old Case of Choroidal Neovascularization in Enhanced S-Cone Syndrome Treated with Ranibizumab

2018 ◽  
Vol 9 (3) ◽  
pp. 510-515 ◽  
Author(s):  
Federica Bertoli ◽  
Silvia Pignatto ◽  
Francesca Rizzetto ◽  
Paolo Lanzetta
Keyword(s):  
Case Report ◽  
Fluorescein Angiography ◽  
Choroidal Neovascularization ◽  
Subretinal Fluid ◽  
Intravitreal Ranibizumab ◽  
Genetic Studies ◽  
Visual Deterioration ◽  
Retinal Degenerations ◽  
The Right ◽  
Enhanced S Cone Syndrome

Introduction: We describe the youngest case of enhanced S-cone syndrome (ESCS) associated with choroidal neovascularization (CNV) successfully treated with intravitreal ranibizumab injections. Case Report: A 5-year-old boy presented with round-shaped fibrotic subretinal lesions in both eyes with surrounding subretinal fluid and progressive visual deterioration in the right eye. Fine foci of increased autofluorescence were observed along the arcades in both eyes. Fluorescein angiography revealed the presence of CNV in his right eye, and treatment with ranibizumab was initiated, with significant improvement in vision. Subsequent electroretinogram examination and genetic studies of the patient and his two younger siblings confirmed the diagnosis of ESCS. Conclusion: CNV has been reported to occur in different inherited retinal degenerations, including ESCS. Our experience confirms that treatment with ranibizumab in patients with CNV-complicated ESCS can be potentially vision-saving.

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