Long-Term Changes in Visual Acuity and Foveal Thickness after Vitrectomy for Idiopathic Epiretinal Membrane

Purpose: To investigate the correlation between outer and inner retina optical coherence tomography (OCT) biomarkers and visual acuity in patients with idiopathic epiretinal membrane (iERM) and identify which of them may be predictive of visual function. Methods: A retrospective cross-sectional single-center study was conducted that included patients diagnosed with iERM. Spectral domain OCT images were obtained and assessed qualitatively and quantitatively. The association of OCT parameters with best corrected visual acuity was analyzed. Results: Charts of 97 eyes of 97 patients were reviewed. Central foveal thickness, maximal retinal thickness (MRT), photoreceptor outer segment length, outer foveal thickness, ganglion cell-inner plexiform layer complex thickening, inner retinal thickness and inner retinal layer irregularity index were among the major outcome measures. OCT scans were also assessed for the presence of cotton ball sign, ellipsoid zone disruption, ectopic inner foveal layer, disorganization of retinal inner layers (DRIL), intraretinal fluid, subretinal fluid (SRF) and epimacular membrane rip. Univariate analysis showed statistically significant association between all the aforementioned parameters with worse vision, except for cotton ball sign and SRF. Multivariate analysis found that MRT and severe DRIL were strongly correlated with worse vision ( p < 0.001). Conclusion: MRT and severe DRIL should be considered as negative prognostic factors for visual acuity.

Download Full-text

Correlation of Foveal Thickness Measured on Optical Coherence Tomography And Visual Acuity In Eyes with Idiopathic Epiretinal membrane

The Internet Journal of Ophthalmology and Visual Science ◽

10.5580/728 ◽

2010 ◽

Vol 7 (2) ◽

Keyword(s):

Optical Coherence Tomography ◽

Visual Acuity ◽

Epiretinal Membrane ◽

Optical Coherence ◽

Foveal Thickness ◽

Idiopathic Epiretinal Membrane

Download Full-text

Natural History of Idiopathic Epiretinal Membrane in Eyes with Good Vision Assessed by Spectral-Domain Optical Coherence Tomography

Ophthalmologica ◽

10.1159/000437058 ◽

2015 ◽

Vol 234 (2) ◽

pp. 91-100 ◽

Cited By ~ 12

Author(s):

Ik Soo Byon ◽

Gang Yun Pak ◽

Han Jo Kwon ◽

Kyong Ho Kim ◽

Sung Who Park ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Visual Acuity ◽

Natural History ◽

Visual Function ◽

Epiretinal Membrane ◽

Membrane Separation ◽

Early Stage ◽

Optical Coherence ◽

Idiopathic Epiretinal Membrane ◽

History Of

Purpose: To investigate the natural history of idiopathic epiretinal membrane (ERM) in eyes with good visual function using optical coherence tomography (OCT). Methods: Sixty-two eyes of 58 patients with idiopathic ERM, visual acuity of 20/40 or better, and no significant metamorphopsia were included. The best corrected visual acuity (BCVA), central macular thickness (CMT), membrane configuration, and ellipsoid zone signal data over 24 months were retrospectively analyzed. Based on OCT findings, ERM configurations were categorized as global attachment (GA), partial attachment (PA), pseudohole, and vitreomacular traction (VMT). Results: The mean BCVA and CMT did not change significantly between baseline and 24 months. GA, PA, pseudohole, and VMT types were observed in 33, 19, 9, and 1 eye at baseline, and in 20, 22, 10, and 1 eye at 24 months, respectively. A membrane configuration change was noted in 24 eyes (38.7%) during follow-up, and the distribution shifted from GA to the other types (p < 0.001). Six eyes had visual loss due to membrane progression, and 4 eyes had spontaneous membrane separation. Of the 10 eyes with progression or separation, 6 were of the PA type. Conclusions: Although the BCVA remains stable over 2 years in most idiopathic ERM eyes with good visual function at baseline, the membrane configuration may change, affecting visual acuity. The GA type would be an early stage, and the PA type is prone to changes in visual acuity.

Download Full-text