scholarly journals Muscarinic Receptors Are Responsible for the Cholinergic Modulation of Projection Neurons in the Song Production Brain Nucleus RA of Zebra Finches

2017 ◽  
Vol 11 ◽  
Author(s):  
Wei Meng ◽  
Songhua Wang ◽  
Lihua Yao ◽  
Nan Zhang ◽  
Dongfeng Li
Keyword(s):  
Muscarinic Receptors ◽  
Projection Neurons ◽  
Zebra Finches ◽  
Cholinergic Modulation ◽  
Brain Nucleus ◽  
Song Production

scholarly journals Carbachol-Induced Reduction in the Activity of Adult Male Zebra Finch RA Projection Neurons

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Wei Meng ◽  
Song-Hua Wang ◽  
Dong-Feng Li
Keyword(s):  
Membrane Potential ◽  
Adult Male ◽  
Motor Behavior ◽  
Membrane Conductance ◽  
Resting Membrane Potential ◽  
Projection Neurons ◽  
Cholinergic Modulation ◽  
Cholinergic Mechanism ◽  
Song Production

Cholinergic mechanism is involved in motor behavior. In songbirds, the robust nucleus of the arcopallium (RA) is a song premotor nucleus in the pallium and receives cholinergic inputs from the basal forebrain. The activity of projection neurons in RA determines song motor behavior. Although many evidences suggest that cholinergic system is implicated in song production, the cholinergic modulation of RA is not clear until now. In the present study, the electrophysiological effects of carbachol, a nonselective cholinergic receptor agonist, were investigated on the RA projection neurons of adult male zebra finches through whole-cell patch-clamp techniques in vitro. Our results show that carbachol produced a significant decrease in the spontaneous and evoked action potential (AP) firing frequency of RA projection neurons, accompanying a hyperpolarization of the membrane potential, an increase in the evoked AP latency, afterhyperpolarization (AHP) peak amplitude, and AHP time to peak, and a decrease in the membrane input resistance, membrane time constant, and membrane capacitance. These results indicate that carbachol reduces the activity of RA projection neurons by hyperpolarizing the resting membrane potential and increasing the AHP and the membrane conductance, suggesting that the cholinergic modulation of RA may play an important role in song production.

DEVELOPMENT OF A BRAIN NUCLEUS INVOLVED IN SONG PRODUCTION IN ZEBRA FINCHES (TAENIOPYGIA GUTTATA) IS DISRUPTED BY AROCLOR 1248

2008 ◽  
Vol 27 (10) ◽  
pp. 2071 ◽  
Author(s):  
Almira L. Hoogesteijn ◽  
George V. Kollias ◽  
Fred W. Quimby ◽  
Anthony P. De Caprio ◽  
David W. Winkler ◽  
...  
Keyword(s):  
Taeniopygia Guttata ◽  
Zebra Finches ◽  
Aroclor 1248 ◽  
Brain Nucleus ◽  
Song Production

Parvalbumin-positive projection neurons characterise the vocal premotor pathway in male, but not female, zebra finches

2001 ◽  
Vol 917 (2) ◽  
pp. 235-252 ◽  
Author(s):  
J Martin Wild ◽  
Matthew N Williams ◽  
Roderick A Suthers
Keyword(s):  
Projection Neurons ◽  
Zebra Finches ◽  
Positive Projection

scholarly journals Sexually dimorphic SCAMP1 expression in the forebrain motor pathway for song production of juvenile zebra finches

2007 ◽  
Vol 67 (4) ◽  
pp. 474-482 ◽  
Author(s):  
Yu Ping Tang ◽  
Camilla Peabody ◽  
Michelle L. Tomaszycki ◽  
Juli Wade
Keyword(s):  
Sexually Dimorphic ◽  
Zebra Finches ◽  
Motor Pathway ◽  
Song Production

Afferent influences on cell death and birth during development of a cortical nucleus necessary for learned vocal behavior in zebra finches

Development ◽  
1994 ◽  
Vol 120 (1) ◽  
pp. 13-24
Author(s):  
F. Johnson ◽  
S. W. Bottjer
Keyword(s):  
Vocal Learning ◽  
Afferent Input ◽  
Vocal Behavior ◽  
Projection Neurons ◽  
Zebra Finches ◽  
Vocal Development ◽  
Neuron Death ◽  
Cortical Nucleus ◽  
Alternate Source ◽  
Cortical Regions

Forebrain nuclei that control learned vocal behavior in zebra finches are anatomically distinct and interconnected by a simple pattern of axonal pathways. In the present study, we examined afferent regulation of neuronal survival during development of the robust nucleus of the archistriatum (RA). RA projection neurons form the descending motor pathway of cortical vocal-control regions and are believed to be directly involved in vocal production. RA receives afferent inputs from two other cortical regions, the lateral magnocellular nucleus of the anterior neostriatum (lMAN) and the higher vocal center (HVC). However, because the ingrowth of HVC afferent input is delayed, lMAN projection neurons provide the majority of afferent input to RA during early vocal learning. lMAN afferent input to RA is of particular interest because lMAN is necessary for vocal learning only during a restricted period of development. By making lesions of lMAN in male zebra finches at various stages of vocal development (20-60 days of age) and in adults (>90-days old), we asked whether the survival of RA neurons depends on lMAN afferent input, and if so whether such dependence changes over the course of vocal learning. The results showed that removal of lMAN afferent input induced the loss of over 40% of RA neurons among birds in early stages of vocal development (20 days of age). However, lMAN lesions lost the ability to induce RA neuron death among birds in later stages of vocal development (40 days of age and older). These findings indicate that many RA neurons require lMAN afferent input for their survival during early vocal learning, whereas the inability of lMAN lesions to induce RA neuron death in older birds may indicate a reduced requirement for afferent input or perhaps the delayed ingrowth of HVC afferent input (at approx. 35 days of age) provides an alternate source of afferent support. Removal of lMAN afferent input also dramatically increased the incidence of mitotic figures in RA, but only among 20-day-old birds at 2 days post-lesion. The early, acute nature of the mitotic events raises the possibility that cell division in RA may be regulated by lMAN afferent input.

Projection neurons within a vocal motor pathway are born during song learning in zebra finches

Nature ◽  
1988 ◽  
Vol 334 (6178) ◽  
pp. 149-151 ◽  
Author(s):  
Kathy W. Nordeen ◽  
Ernest J. Nordeen
Keyword(s):  
Song Learning ◽  
Projection Neurons ◽  
Zebra Finches ◽  
Motor Pathway

scholarly journals Behavioural responses to video and live presentations of females reveal a dissociation between performance and motivational aspects of birdsong

2019 ◽  
Author(s):  
Logan S. James ◽  
R. Fan ◽  
J.T. Sakata
Keyword(s):  
Courtship Song ◽  
Zebra Finches ◽  
Acoustic Features ◽  
Neural Models ◽  
Song Production ◽  
And Performance ◽  
And Control ◽  
Video Presentations ◽  
Insight Into ◽  
Social Behaviours

ABSTRACTUnderstanding the regulation of social behavioural expression requires insight into motivational and performance aspects of social behaviours. While a number of studies have independently investigated motivational or performance aspects of social behaviours, few have examined how these aspects relate to each other. By comparing behavioural variation in response to live or video presentations of conspecific females, we analysed how variation in the motivation to produce courtship song covaries with variation in performance aspects of courtship song in male zebra finches (Taeniopygia guttata). Consistent with previous reports, we observed that male zebra finches were less motivated to produce courtship songs to videos of females than to live presentations of females. However, we found that acoustic features that reflect song performance were indistinguishable between songs produced to videos of females and songs produced to live presentations of females. For example, songs directed at video presentations of females were just as fast and stereotyped as songs directed at live females. These experimental manipulations and correlational analyses reveal a dissociation between motivational and performance aspects of birdsong and suggest a refinement of neural models of song production and control. In addition, they support the efficacy of videos to study both motivational and performance aspects of social behaviours.

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