scholarly journals Corrigendum: Pipeline Embolization Device for the Treatment of Unruptured Intracranial Dissecting Aneurysms

2022 ◽  
Vol 12 ◽  
Author(s):  
Jigang Chen ◽  
Mushun Tao ◽  
Jiangli Han ◽  
Xin Feng ◽  
Fei Peng ◽  
...  
2019 ◽  
Vol 10 ◽  
Author(s):  
Jiejun Wang ◽  
Yisen Zhang ◽  
Ming Lv ◽  
Xinjian Yang ◽  
Zhongbin Tian ◽  
...  

2017 ◽  
Vol 42 (6) ◽  
pp. E4 ◽  
Author(s):  
Purvee D. Patel ◽  
Nohra Chalouhi ◽  
Elias Atallah ◽  
Stavropoula Tjoumakaris ◽  
David Hasan ◽  
...  

The Pipeline embolization device (PED) is the most widely used flow diverter in endovascular neurosurgery. In 2011, the device received FDA approval for the treatment of large and giant aneurysms in the internal carotid artery extending from the petrous to the superior hypophyseal segments. However, as popularity of the device grew and neurosurgeons gained more experience, its use has extended to several other indications. Some of these off-label uses include previously treated aneurysms, acutely ruptured aneurysms, small aneurysms, distal circulation aneurysms, posterior circulation aneurysms, fusiform aneurysms, dissecting aneurysms, pseudoaneurysms, and even carotid-cavernous fistulas. The authors present a literature review of the safety and efficacy of the PED in these off-label uses.


2016 ◽  
Vol 63 (5) ◽  
pp. 1371-1374 ◽  
Author(s):  
Emma F. Sczudlo ◽  
Carolina Benavides-Baron ◽  
Joseph T. Ho ◽  
George P. Teitelbaum

Neurosurgery ◽  
2014 ◽  
Vol 75 (4) ◽  
pp. 364-374 ◽  
Author(s):  
Sebastian Fischer ◽  
Marta Aguilar Perez ◽  
Wiebke Kurre ◽  
Guido Albes ◽  
Hansjörg Bäzner ◽  
...  

Abstract BACKGROUND: Flow-diverting stents offer a promising treatment option for complex aneurysms. OBJECTIVE: To evaluate the safety and efficacy of the Pipeline embolization device (PED) in the treatment of fusiform and dissecting aneurysms. METHODS: Sixty-five consecutive patients with 69 fusiform and dissecting aneurysms underwent endovascular treatment with the use of the PED. Target vessels included the internal carotid artery (n = 28), middle cerebral artery (n = 2), anterior cerebral artery (n = 1), vertebral artery (n = 20), basilar artery (n = 17), and posterior cerebral artery (n = 1). An average of 3.0 PEDs per target vessel were deployed. RESULTS: Exclusion of the aneurysm(s) immediately after PED deployment was not observed. Angiographic follow-up examinations were performed in 63/65 patients (67/69 lesions). They showed complete cure of the target lesion in the first follow-up angiography (3.4 months mean interval) in 24 (36%) cases, partial elimination in 30 (45%), and no improvement in 13 (19%). After the latest follow-up (>1 digital subtraction angiography, n = 49, 27.4 months mean interval) complete cure of the target lesion was observed in 33 (67%), partial elimination in 14 (29%), and no change in 2 (4%). Taking all follow-up examinations together, 39/67 (58%) aneurysms were cured. The morbidity and mortality in the entire series were 5% and 8%, respectively. CONCLUSION: Flow diverters offer a promising treatment option in fusiform and dissecting aneurysms. The introduction of flow diverters with different densities might help to identify the optimal amount of coverage needed given different anatomic presentations of fusiform and dissecting aneurysms.


2016 ◽  
Vol 23 (2) ◽  
pp. 151-153
Author(s):  
Yupeng Zhang ◽  
Shikai Liang ◽  
Chuhan Jiang

Unruptured vertebral arteries dissecting aneurysms have a benign clinical course. The most common symptoms compromise headache, neck pain, dizziness and vomiting. The optimal endovascular treatment option remains controversial. Reconstructive techniques have many advantages over deconstructive ones since the advent of flow diverters such as the Pipeline embolization device (PED). Here, we present a case successfully treated with a PED through a combination of the radial access and advancement of the Marksman catheter into the contralateral vertebral artery due to the special angio-architecture of the patient.


2021 ◽  
Vol 12 ◽  
Author(s):  
Jigang Chen ◽  
Mushun Tao ◽  
Jiangli Han ◽  
Xin Feng ◽  
Fei Peng ◽  
...  

Background: Intracranial dissecting aneurysms (IDAs) are rare but pose significant challenges to treatment. The pipeline embolization device (PED) has been demonstrated to be an effective treatment option with excellent outcomes. Herein, we report our experience with patients treated with the PED for unruptured IDAs.Methods: We retrospectively reviewed our hospital database and identified patients who were treated with PEDs for unruptured IDAs between March 2016 and September 2020. Data including demographics, clinical presentation, aneurysm characteristics, procedural details, intra- or peri-procedural complications, and follow-up details were collected.Results: Eighty patients (61 men, 76.25%) were treated with PED for unruptured IDAs. The most common symptoms were headache (34, 42.5%), dizziness (29, 36.25%), and nausea or vomiting (15, 18.75%). Of these patients, 73 had one aneurysm, and seven harbored two aneurysms. All of them achieved successful PED deployment. Six patients experienced intra- or peri-procedural complications including perforator artery occlusion, thromboembolic, hemorrhagic events, and falling of the stent into the aneurysm sac. Follow-up with digital subtractive angiography was available for 29 patients with a median of 6 months, and 28 (96.56%) patients had aneurysm occlusion. Late thrombosis occurred in four patients, and two of them had unfavorable outcomes. Clinical follow-up showed that a favorable clinical outcome was achieved in 76 (95%) patients, and the mortality rate was 3.75%.Conclusion: Treating unruptured IDAs is safe and effective with long-term favorable clinical and angiographic outcomes. However, the complications of this treatment should be noted. Careful selection of appropriate patients and individualized antiplatelet therapy might be needed.


2015 ◽  
Vol 8 (10) ◽  
pp. 1048-1051 ◽  
Author(s):  
Anna Luisa Kühn ◽  
Peter Kan ◽  
Francesco Massari ◽  
J Diego Lozano ◽  
Samuel Y Hou ◽  
...  

BackgroundDissecting aneurysms of the vertebral artery (VA) are difficult to treat using current surgical and endovascular techniques.ObjectiveTo analyze retrospectively the efficacy and safety of flow diverters in the treatment of dissecting aneurysms of the vertebral artery.MethodsWe identified six patients with six unruptured VA dissecting aneurysms either arising from the V4 or V3–V4 junction that were treated with the Pipeline embolization device (PED) at our institution between July 2012 and February 2015. Among other parameters, technical feasibility of the procedure, procedure-related complications, angiographic results, and clinical outcome were evaluated.ResultsPED placement was achieved in all cases and immediate angiography follow-up demonstrated intra-aneurysmal contrast stasis with parent artery preservation. A temporary episode of dysarthria was noted in one patient. Major procedure-related complications were not observed. The 6-month follow-up (n=6) demonstrated complete/near-complete aneurysm obliteration in five patients and partial obliteration in one. At the 1-year follow-up (n=5) stable complete aneurysm occlusion was seen in two patients. Two cases showed progression from near complete occlusion and partial occlusion at 6 months to complete occlusion and near complete occlusion. One cases showed unchanged near complete occlusion. No aneurysmal bleeding, in-stent stenosis or thromboembolic complication was seen. National Institutes of Health Stroke Scale and modified Rankin scale scores remained unchanged from admission to discharge.ConclusionsOur preliminary experience with the use of PED for the treatment of intradural VA dissecting aneurysms shows promising short-term results, making this technique a feasible and safe treatment option in patients suitable for this approach. However, long-term and larger cohort studies are needed to validate these results.


1995 ◽  
Vol 23 (5) ◽  
pp. 391-398
Author(s):  
Hirotoshi SANO ◽  
Yoko KATO ◽  
Isao OHKUMA ◽  
Takashi NINOMIYA ◽  
Jie ZHOU ◽  
...  

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