scholarly journals F-18 FDG PET/CT Imaging in Normal Variants, Pitfalls and Artifacts in the Abdomen and Pelvis

2022 ◽  
Vol 1 ◽  
Author(s):  
Mboyo D. T. Vangu ◽  
Jaleelat I. Momodu
Keyword(s):  
Fdg Pet ◽  
Multimodality Imaging ◽  
Ct Imaging ◽  
Variable Degree ◽  
Normal Variants ◽  
Pet Ct ◽  
Technical Artifacts ◽  
Fdg Pet Ct ◽  
Metallic Hardware ◽  
Imaging Pitfalls

Since its introduction into clinical practice, multimodality imaging has revolutionized diagnostic imaging for both oncologic and non-oncologic pathologies. 18F-fluorodeoxyglucose (18F-FDG) PET/CT imaging which takes advantage of increased anaerobic glycolysis that occurs in tumor cells (Warburg effect) has gained significant clinical relevance in the management of most, if not all oncologic conditions. Because FDG is taken by both normal and abnormal tissues, PET/CT imaging may demonstrate several normal variants and imaging pitfalls. These may ultimately impact disease detection and diagnostic accuracy. Imaging specialists (nuclear medicine physicians and radiologists) must demonstrate a thorough understanding of normal and physiologic variants in the distribution of 18F-FDG; including potential imaging pitfalls and technical artifacts to minimize misinterpretation of images. The normal physiologic course of 18F-FDG results in a variable degree of uptake in the stomach, liver, spleen, small and large bowel. Urinary excretion results in renal, ureteric, and urinary bladder uptake. Technical artifacts can occur due to motion, truncation as well as the effects of contrast agents and metallic hardware. Using pictorial illustrations, this paper aims to describe the variants of physiologic 18F-FDG uptake that may mimic pathology as well as potential benign conditions that may result in misinterpretation of PET/CT images in common oncologic conditions of the abdomen and pelvis.

18F-FDG PET/CT Imaging: Normal Variants, Pitfalls and Artefacts

2021 ◽  
pp. 39-62
Author(s):  
Kanhaiyalal Agrawal ◽  
Gopinath Gnanasegaran ◽  
Evangelia Skoura ◽  
Alexis Corrigan ◽  
Teresa Szyszko
Keyword(s):  
Fdg Pet ◽  
Ct Imaging ◽  
Normal Variants ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

18F-FDG PET/CT Imaging: Normal Variants, Pitfalls and Artefacts

2016 ◽  
pp. 55-77
Author(s):  
Kanhaiyalal Agrawal ◽  
Gopinath Gnanasegaran ◽  
Evangelia Skoura ◽  
Alexis Corrigan ◽  
Teresa A. Szyszko
Keyword(s):  
Fdg Pet ◽  
Ct Imaging ◽  
Normal Variants ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

18F-FDG PET/CT Imaging: Normal Variants, Pitfalls and Artefacts

2016 ◽  
pp. 69-93
Author(s):  
Kanhaiyalal Agrawal ◽  
Gopinath Gnanasegaran ◽  
Evangelia Skoura ◽  
Alexis Corrigan ◽  
Teresa A. Szyszko
Keyword(s):  
Fdg Pet ◽  
Ct Imaging ◽  
Normal Variants ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

Integrated FDG PET-CT imaging improves staging in malignant pleural mesothelioma

2007 ◽  
Author(s):  
Stefan Krüger ◽  
S. Pauls ◽  
Felix M. Mottaghy ◽  
Andreas K. Buck ◽  
Hubert Schelzig ◽  
...  
Keyword(s):  
Malignant Pleural Mesothelioma ◽  
Fdg Pet ◽  
Ct Imaging ◽  
Pleural Mesothelioma ◽  
Pet Ct ◽  
Fdg Pet Ct

Dual Time F-18 FDG PET/CT Imaging in the Diagnosis of Renal Cell Cancer

2014 ◽  
Vol 10 (2) ◽  
pp. 134-139 ◽  
Author(s):  
Savas Karyagar ◽  
Zehra Koc ◽  
Sevda Karyagar ◽  
Tamer Ozulker ◽  
Cevat Topal ◽  
...  
Keyword(s):  
Renal Cell Cancer ◽  
Fdg Pet ◽  
Renal Cell ◽  
Cell Cancer ◽  
Ct Imaging ◽  
Pet Ct ◽  
Fdg Pet Ct

FDG-PET/CT Imaging of Infected Bones and Prosthetic Joints

2015 ◽  
Vol 3 (3) ◽  
pp. 225-229 ◽  
Author(s):  
Sandip Basu ◽  
Thomas C. Kwee ◽  
Soren Hess
Keyword(s):  
Fdg Pet ◽  
Ct Imaging ◽  
Prosthetic Joints ◽  
Pet Ct ◽  
Fdg Pet Ct

scholarly journals FDG PET/CT imaging of desmoplastic small round cell tumor: findings at staging, during treatment and at follow-up

2015 ◽  
Vol 45 (9) ◽  
pp. 1308-1315 ◽  
Author(s):  
Austin Ostermeier ◽  
M. Beth McCarville ◽  
Fariba Navid ◽  
Scott E. Snyder ◽  
Barry L. Shulkin
Keyword(s):  
Fdg Pet ◽  
Ct Imaging ◽  
Cell Tumor ◽  
Round Cell ◽  
Round Cell Tumor ◽  
Small Round Cell Tumor ◽  
Small Round Cell ◽  
Pet Ct ◽  
Fdg Pet Ct

scholarly journals Quantitative analysis of myocardial metabolic heterogeneity is superior to visual assessment for the detection of active cardiac sarcoidosis by F-18 FDG PET-CT imaging

2021 ◽  
Vol 22 (Supplement_1) ◽  
Author(s):  
M Malik ◽  
M Yazdani ◽  
SM Gould ◽  
E Reyes
Keyword(s):  
Fdg Pet ◽  
Cardiac Sarcoidosis ◽  
Visual Assessment ◽  
Ct Imaging ◽  
Myocardial Inflammation ◽  
Fdg Uptake ◽  
Pet Ct ◽  
Metabolic Heterogeneity ◽  
Fdg Pet Ct

Abstract Funding Acknowledgements Type of funding sources: None. Background Myocardial inflammation may occur in the context of a multisystem disease such as sarcoidosis, adversely affecting prognosis. A definitive diagnosis of cardiac sarcoidosis (CS) is essential to implementing life-saving treatment but this is complicated by the invasive nature of endomyocardial biopsy (EMB) and its low accuracy. Positron emission tomography (PET) assists in diagnosis, which relies on visual interpretation of myocardial F-18 FDG uptake. The value of quantitative analysis and its application to clinical practice remain uncertain. Purpose To investigate the power of quantitative F-18 FDG PET-CT imaging analysis for detecting CS in patients with suspected disease. Methods All patients underwent F-18 FDG PET-CT after a 24-hour low-carbohydrate diet and 15-hour fasting as part of their diagnostic work-up for suspected cardiac inflammation. Cardiovascular magnetic resonance acted as gatekeeper to PET-CT in 8 of every 10 scans. Myocardial F-18 FDG uptake was assessed qualitatively and quantitatively using both manually drawn regions of interest and automatic polar maps to measure global and segmental standardised F-18 FDG uptake values (SUV).  The coefficient of variation (CoV) was calculated to determine uptake heterogeneity. To confirm diagnosis, follow-up data regarding disease progression, further testing and treatment were collected. To allow for sufficient follow-up time, the first 40 consecutive patients from a prospective registry (n= 214; Sep 2017-Jun 2020) were included. Results A comprehensive clinical picture was obtained successfully in 37 patients (median [IQR], 17 [13.5] months) and a final diagnosis of CS reached in 7 (disease prevalence, 19%). EMB was performed in 2 patients only while 3 underwent PPM/ICD implantation. Significant predictors of CS were fulfilment of Japanese Ministry of Health and Welfare criteria (Wald, 6.44; p = 0.01) and left ventricular dysfunction (Wald 6.72; p = 0.01). Qualitative F-18 FDG PET-CT had a high negative (95%) but low positive (45%) predictive value for CS (sensitivity, 83%; specificity, 77%). F-18 FDG SUV CoV was the strongest imaging predictor (Wald, 6.77; p = 0.009) and was significantly higher in CS than non-CS (CoV median [quartiles], 0.26 [0.21, 0.36] and 0.12 [0.11, 0.14] respectively; p = 0.004). As per ROC curve analysis (AUC, 0.84), a CoV threshold of 0.20 was highly specific (93%) and sensitive (86%) for CS. Conclusion In a referring population with a low prevalence of cardiac sarcoidosis, F-18 FDG PET-CT imaging is sensitive for the detection of myocardial inflammation with active disease unlikely in patients with a negative scan. Quantitative evaluation of metabolic heterogeneity within the myocardium provides a strong, independent marker of active disease and should be considered alongside visual assessment.

scholarly journals 18F-FDG PET/CT imaging findings of multiple solitary fibrous tumor

Medicine ◽  
2019 ◽  
Vol 98 (32) ◽  
pp. e16743
Author(s):  
Xiaofei Liu ◽  
Wenhua Zhu ◽  
Xiaohong Zhou ◽  
Hao Yao ◽  
Jiagui Su ◽  
...  
Keyword(s):  
Solitary Fibrous Tumor ◽  
Fdg Pet ◽  
Ct Imaging ◽  
Imaging Findings ◽  
Pet Ct ◽  
18F Fdg ◽  
Fibrous Tumor ◽  
Fdg Pet Ct
Sign in / Sign up

Export Citation Format

Share Document