scholarly journals Fragile X mental retardation 1 and Filamin A interact genetically in Drosophila long-term memory

2010 ◽  
Vol 3 ◽  
Author(s):  
Francois Bolduc
Keyword(s):  
Mental Retardation ◽  
Fragile X ◽  
Long Term Memory ◽  
Filamin A ◽  
Term Memory ◽  
Fragile X Mental Retardation

scholarly journals Short- and Long-Term Memory Are Modulated by Multiple Isoforms of the Fragile X Mental Retardation Protein

2010 ◽  
Vol 30 (19) ◽  
pp. 6782-6792 ◽  
Author(s):  
P. Banerjee ◽  
B. P. Schoenfeld ◽  
A. J. Bell ◽  
C. H. Choi ◽  
M. P. Bradley ◽  
...  
Keyword(s):  
Mental Retardation ◽  
Fragile X ◽  
Long Term Memory ◽  
Term Memory ◽  
Fragile X Mental Retardation ◽  
Mental Retardation Protein ◽  
Short And Long Term

scholarly journals Excess protein synthesis in Drosophila Fragile X mutants impairs long-term memory

2008 ◽  
Vol 11 (10) ◽  
pp. 1143-1145 ◽  
Author(s):  
François V Bolduc ◽  
Kimberly Bell ◽  
Hilary Cox ◽  
Kendal S Broadie ◽  
Tim Tully
Keyword(s):  
Protein Synthesis ◽  
Fragile X ◽  
Long Term Memory ◽  
Term Memory

Focal areas of a high rate of fragile X in Indonesia: a long term follow up

2019 ◽  
Vol 5 (2) ◽  
pp. 67-68
Author(s):  
Sultana MH Faradz ◽  
Tri Indah Winarni
Keyword(s):  
Mental Retardation ◽  
Behavioral Problems ◽  
Fragile X ◽  
Autism Spectrum ◽  
High Rate ◽  
Learning Ability ◽  
Fragile X Mental Retardation ◽  
Cgg Repeats ◽  
Long Term Follow Up

Fragile X syndrome (FXS) is the most common cause of inherited intellectual disability (ID) and a leading cause of autism spectrum disorder (ASD). FXS is caused by an expansion of CGG repeats >200 in the 5′ untranslated region of the promotor region fragile X mental retardation 1 gene (FMR1), which is located on Xq27.3.  The abnormal CGG expansion leads to methylation and transcriptional silencing of the FMR1 gene, resulting in a reduction or loss of fragile X mental retardation 1 protein (FMRP) and causes long, thin, and immature dendritic spines, which lead to deficits in cognitive function, behavioral problems, and learning ability

scholarly journals Dynamic Translational and Proteasomal Regulation of Fragile X Mental Retardation Protein Controls mGluR-Dependent Long-Term Depression

Neuron ◽  
2006 ◽  
Vol 51 (4) ◽  
pp. 441-454 ◽  
Author(s):  
Lingfei Hou ◽  
Marcia D. Antion ◽  
Daoying Hu ◽  
Corinne M. Spencer ◽  
Richard Paylor ◽  
...  
Keyword(s):  
Mental Retardation ◽  
Fragile X ◽  
Long Term Depression ◽  
Fragile X Mental Retardation ◽  
Mental Retardation Protein

scholarly journals Multiple Drug Treatments That Increase cAMP Signaling Restore Long-Term Memory and Aberrant Signaling in Fragile X Syndrome Models

2016 ◽  
Vol 10 ◽  
Author(s):  
Catherine H. Choi ◽  
Brian P. Schoenfeld ◽  
Aaron J. Bell ◽  
Joseph Hinchey ◽  
Cory Rosenfelt ◽  
...  
Keyword(s):  
Fragile X Syndrome ◽  
Fragile X ◽  
Camp Signaling ◽  
Multiple Drug ◽  
Long Term Memory ◽  
Term Memory ◽  
Drug Treatments
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