scholarly journals Predictive Value of Red Blood Cell Distribution Width, Mean Platelet Volume and Platelet Distribution Width in Children with Acute Appendicitis

Children ◽  
2021 ◽  
Vol 8 (11) ◽  
pp. 1041
Author(s):  
Jelena Antić ◽  
Radoica Jokić ◽  
Svetlana Bukarica ◽  
Ivana Lukić ◽  
Dejan Dobrijević ◽  
...  
Keyword(s):  
Acute Appendicitis ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Complicated Appendicitis ◽  
Important Predictor ◽  
Cell Distribution ◽  
Platelet Distribution Width ◽  
Platelet Volume ◽  
Distribution Width ◽  
Red Blood Cell Distribution

Background and Objectives: Acute appendicitis in pediatric patients is one of the most common surgical emergencies, but the early diagnosis still remains challenging. The aim of this study was to determine the predictive value of Red blood cell distribution width (RDW), Mean platelet volume (MPV) and Platelet distribution width (PDW) in children with acute appendicitis. Materials and Methods: This study was a retrospective assessment of laboratory findings (RDW, MPV, PDW) of patients who underwent surgical treatment for acute appendicitis from January 2019 to December 2020. Result: During this period, 223 appendectomies were performed at our Institute. In 107 (43%) cases appendicitis was uncomplicated, while in 116 (46.6%) it was complicated. WBC and RDW/MPV ratio were significant parameters for the diagnosis of acute appendicitis with cut-off values of 12.86 (susceptibility: 66.3%; specificity: 73.2%) and 1.64 (susceptibility: 59.8%; specificity: 71.9%), respectively. WBC and RDW/RBC ratio were independent variables for the diagnosis of complicated appendicitis. The cut-off values were 15.05 for WBC (sensitivity: 60.5%; specificity: 70.7%) and 2.5 for RDW/RBC ratio (sensitivity: 72%; specificity: 52.8%). Conclusions: WBC is an important predictor of appendicitis and complicated appendicitis. RDW, MPV and PDW alone have no diagnostic value in pediatric acute appendicitis or predicting the degree of appendix inflammation. However, the RDW/MPV ratio can be an important predictor of appendix inflammation, with higher values in patients with more severe appendix inflammation. RDW/RBC ratio may be an important predictor of complicated appendicitis.

Can whole-blood parameters be used in follow-up of children with rheumatic valvular heart disease?

2016 ◽  
Vol 27 (4) ◽  
pp. 764-769
Author(s):  
Derya Karpuz ◽  
Dilek Giray ◽  
Abdullah Ozyurt ◽  
Gulcin Bozlu ◽  
Selma Unal ◽  
...  
Keyword(s):  
Heart Disease ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Mean Platelet Volume ◽  
Cell Distribution ◽  
Platelet Distribution Width ◽  
Platelet Volume ◽  
Distribution Width ◽  
Red Blood Cell Distribution ◽  
Rheumatic Heart

AbstractObjectivesThe aim of the present study was to investigate the relationships between red blood cell distribution width, platelet distribution width, and mean platelet volume and the presence and severity of valvular involvement in patients with rheumatic heart disease.MethodsBetween April, 2012 and December, 2015, 151 patients who were admitted to the Pediatric Cardiology Unit with diagnosis of rheumatic heart disease and 148 healthy children were included to our study. Transthoracic echocardiography for all children was performed, and the values of red blood cell distribution width, platelet distribution width, and mean platelet volume, besides other blood count parameters, erythrocyte sedimentation rate, and C-reactive protein levels were recorded.ResultsRed blood cell distribution width, platelet distribution width, mean platelet volume, and C-reactive protein levels were significantly higher in patients with rheumatic heart disease when compared with healthy controls (p<0.01). Red blood cell distribution width was positively correlated with both C-reactive protein (r=0.271, p=0.035) and erythrocyte sedimentation rate (r=0.308, p=0.006). When single valve involvement was compared with both aortic valve and mitral valve involvement in the study group, red blood cell distribution width and platelet distribution width were higher in patients with double valve involvement; however, this was not statistically significant (p>0.05).ConclusionThis is the first study in children with rheumatic heart disease that demonstrated significantly increased red blood cell distribution width, platelet distribution width, and mean platelet volume levels, as well as evaluated all three parameters together. Furthermore, red blood cell distribution width values in the chronical period of acute rheumatic fever, due to the positive correlation with the other chronic inflammatory markers, may help make the diagnosis in children.

Diagnostic value of red blood cell distribution width in pediatric acute appendicitis

2016 ◽  
Vol 58 (3) ◽  
pp. 202-205 ◽  
Author(s):  
Gulcin Bozlu ◽  
Hakan Taskinlar ◽  
Selma Unal ◽  
Mehmet Alakaya ◽  
Ali Nayci ◽  
...  
Keyword(s):  
Acute Appendicitis ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Diagnostic Value ◽  
Cell Distribution ◽  
Distribution Width ◽  
Red Blood Cell Distribution

scholarly journals Mean platelet volume and red blood cell distribution width is associated with prognosis in premature neonates with sepsis

Open Medicine ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. 1175-1181
Author(s):  
Na Cai ◽  
Zhi Qiang Chen ◽  
Min Tao ◽  
Wen Ting Fan ◽  
Wei Liao
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Late Onset ◽  
Cell Distribution ◽  
Platelet Volume ◽  
Distribution Width ◽  
Premature Neonates ◽  
Survivor Group ◽  
Late Onset Sepsis ◽  
Red Blood Cell Distribution

Abstract Objective To evaluate the prognostic value of the mean platelet volume (MPV) and red blood cell distribution width (RDW) in sepsis among premature neonates. Methods This was a retrospective cohort study conducted in the neonatal intensive care unit between May 2015 and May 2020. Premature neonates with late-onset sepsis were enrolled. The demographic data, blood cell count analysis, C-reactive protein, and blood culture were compared between survivors and non-survivors. Results A total of 73 premature neonates with sepsis in the survivor group and 10 cases in the non-survivor group. Significant differences were observed between the survivor and non-survivor groups with regard to birth weight, MPV, and RDW (P < 0.05). The results of binomial stepwise logistic regression suggested that MPV (OR = 3.226, P = 0.017 < 0.05) and RDW (OR = 2.058, P = 0.019 < 0.05) were independent predictor for prognosis in preterm with sepsis. A receiver operating characteristic analysis showed that the areas under the curves were 0.738 for MPV alone, 0.768 for RDW alone, and 0.854 for MPV combined with RDW. Conclusion MPV and RDW were independent predictors of prognosis and the combination of the two helps in predicting the prognosis of preterm with late-onset sepsis in the early stage.

scholarly journals Analysis of mean platelet volume and red blood cell distribution width in recurrent epistaxis

2018 ◽  
Vol 18 (2) ◽  
pp. 67-70 ◽  
Author(s):  
Ali Ekber Karabulut ◽  
Yunsur Çevik ◽  
Emine Emektar ◽  
Şeref Kerem Çorbacioğlu ◽  
Seda Dağar ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Mean Platelet Volume ◽  
Cell Distribution ◽  
Platelet Volume ◽  
Distribution Width ◽  
Recurrent Epistaxis ◽  
Red Blood Cell Distribution
Sign in / Sign up

Export Citation Format

Share Document