scholarly journals Influence of Antihistamines on Basophil Activation Test in Food Allergy to Milk and Egg

Diagnostics ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 44
Author(s):  
Eleonora Nucera ◽  
Riccardo Inchingolo ◽  
Rosario Nicotra ◽  
Manuela Ferraironi ◽  
Anna Giulia Ricci ◽  
...  
Keyword(s):  
Food Allergy ◽  
Food Challenge ◽  
Basophil Activation Test ◽  
Basophil Activation ◽  
Double Blind ◽  
Positive Skin ◽  
Activation Test ◽  
History Of ◽  
Ige Mediated ◽  
Food Allergy Diagnosis

Background: The basophil activation test (BAT) is used to improve the accuracy of food allergy diagnosis. To date, the influence of antiallergic drugs on BAT reactivity is poorly investigated. The aim of the study was to investigate if BAT results were influenced by antihistamine intake for 3 months in a cohort of patients with IgE-mediated food allergy to milk or egg. Methods: A retrospective, single-center, observational study was performed. We enrolled subjects with history of hypersensitivity reaction after specific food ingestion, positive skin prick tests and specific IgEs, concomitant allergic rhinitis, and, contraindication to the double-blind, placebo-controlled food challenge due to personal history of systemic reactions related to the ingestion of culprit food. Validated allergens (α-lactoalbumin, β-lactoglobulin, casein, egg white, and yolk) for BAT were used. Results: Thirty-nine patients with well-documented food symptoms and positive allergological workup were included in the study. BAT was positive in 29 patients. The mean percentages of CD63+ expression to specific culprit allergen did not change after the administration of drugs. Conclusions: This was the first study assessing the effects of oral antihistamines on basophil reactivity in cow’s milk and egg food allergy. Antihistamines do not interfere with BAT results.

scholarly journals Basophil Activation Test in IgE-Mediated Food Allergy: Should We Follow the Flow?

2016 ◽  
Vol 3 (2) ◽  
pp. 158-168 ◽  
Author(s):  
M. A. Faber ◽  
V. Sabato ◽  
I. I. Decuyper ◽  
A. L. Van Gasse ◽  
M. M. Hagendorens ◽  
...  
Keyword(s):  
Food Allergy ◽  
Basophil Activation Test ◽  
Basophil Activation ◽  
Activation Test ◽  
Ige Mediated

The Basophil Activation Test reduces the need for a food challenge test in children suspected of IgE-mediated cow's milk allergy

2018 ◽  
Vol 49 (3) ◽  
pp. 350-356 ◽  
Author(s):  
Janneke Ruinemans-Koerts ◽  
Yvonne Schmidt-Hieltjes ◽  
Ad Jansen ◽  
Huub F.J. Savelkoul ◽  
Annejet Plaisier ◽  
...  
Keyword(s):  
Challenge Test ◽  
Food Challenge ◽  
Basophil Activation Test ◽  
Basophil Activation ◽  
Cow’S Milk ◽  
Milk Allergy ◽  
Activation Test ◽  
Cow's Milk ◽  
Ige Mediated ◽  
Food Challenge Test

Basophil activation test in food allergy

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Tarun Keswani ◽  
Sarita U. Patil
Keyword(s):  
Food Allergy ◽  
Basophil Activation Test ◽  
Basophil Activation ◽  
Activation Test

Usefulness of basophil activation test for the diagnosis of IgE mediated hypersensitivity to tetanus toxoid vaccine

2018 ◽  
Vol 454 ◽  
pp. 86-88 ◽  
Author(s):  
Blanca Herreros ◽  
Yesica Méndez ◽  
Francisco Feo-Brito ◽  
José Miguel Urra
Keyword(s):  
Tetanus Toxoid ◽  
Basophil Activation Test ◽  
Basophil Activation ◽  
Activation Test ◽  
Ige Mediated

Basophil Activation Test for Diagnosis of Food Allergy

2008 ◽  
Vol 121 (2) ◽  
pp. S250-S250
Author(s):  
V VALDIMARSSON ◽  
S SIGURDARDOTTIR ◽  
I SKAFTADOTTIR ◽  
M CLAUSEN ◽  
B LUDVIGSSON
Keyword(s):  
Food Allergy ◽  
Basophil Activation Test ◽  
Basophil Activation ◽  
Activation Test

scholarly journals Basophil Activation Test in Amiodarone Hypersensitivity and Non–IgE-Mediated Allergy

2019 ◽  
Vol 29 (5) ◽  
pp. 401-402
Author(s):  
A Vella ◽  
G Bjørklund ◽  
S Chirumbolo
Keyword(s):  
Basophil Activation Test ◽  
Basophil Activation ◽  
Activation Test ◽  
Ige Mediated

scholarly journals The basophil activation test reflects the severity and the threshold of allergic reactions to peanut – a double-blind-placebo-controlled peanut challenge study

2015 ◽  
Vol 5 (S3) ◽  
Author(s):  
Alexandra Santos ◽  
Abdel Douiri ◽  
Alick Stephens ◽  
Suzana Radulovic ◽  
George du Toit ◽  
...  
Keyword(s):  
Basophil Activation Test ◽  
Basophil Activation ◽  
Allergic Reactions ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Activation Test ◽  
Challenge Study

scholarly journals Prevalence and Clinical Impact of IgE-Mediated Food Allergy in School Children With Asthma: A Double-Blind Placebo-Controlled Food Challenge Study

2015 ◽  
Vol 7 (6) ◽  
pp. 547 ◽  
Author(s):  
Aneta Krogulska ◽  
Jarosław Dynowski ◽  
Marzena Funkowicz ◽  
Beata Małachowska ◽  
Krystyna Wąsowska-Królikowska
Keyword(s):  
Food Allergy ◽  
School Children ◽  
Food Challenge ◽  
Clinical Impact ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Challenge Study ◽  
Children With Asthma ◽  
Ige Mediated

scholarly journals Late Type of Bronchial Response to Milk Ingestion Challenge: A Comparison of Open and Double-Blind Challenge

2012 ◽  
Vol 2012 ◽  
pp. 1-11
Author(s):  
Zdenek Pelikan
Keyword(s):  
Food Allergy ◽  
Food Challenge ◽  
Diagnostic Value ◽  
Skin Tests ◽  
Natural Food ◽  
Double Blind ◽  
Positive Skin ◽  
Asthma Patients ◽  
Natural Foods ◽  
Milk Ingestion

Background. In some asthmatics the food allergy, for example, to milk, can participate in their bronchial complaints. The role of food allergy should be confirmed definitively by food ingestion challenge performed by an open challenge with natural foods (OFICH) or by a double-blind placebo-controlled food challenge (DBPCFC). Objectives. To investigate the diagnostic value of these techniques for confirmation of a suspected milk allergy in bronchial asthma patients. Methods. In 54 asthmatics with a positive history and/or positive skin tests for milk the 54 OFICH, and DBPCFC, were performed in combination with spirometry. Results. The 54 patients developed 39 positive late asthmatic responses (LAR) and 15 negative asthmatic responses to OFICH and 40 positive LARs and 14 negative responses to DBPCFC. The overall correlation between the OFICH and DBPCFC was statistically significant (). Conclusions. This study has confirmed the existence of LAR to milk ingestion performed by OFICH and DBPCFC in combination with spirometry. The results obtained by both the techniques did not differ significantly. The OFICH with natural food combined with monitoring of objective parameter(s), such as spirometry, seems to be a suitable method for detection of the food allergy in asthmatics. The DBPCFC can be performed as an additional check, if necessary.

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