scholarly journals Inclusion Complex of Iloperidone with sulfobutyl ether beta-cyclodextrin: Characterization and dissolution studies

2020 ◽  
Author(s):  
Rupali Bhadale ◽  
Vaishali Londhe
Keyword(s):  
Inclusion Complex ◽  
Dissolution Studies ◽  
Beta Cyclodextrin ◽  
Sulfobutyl Ether

Investigation of inclusion complex of honokiol with sulfobutyl ether-β-cyclodextrin

2014 ◽  
Vol 113 ◽  
pp. 9-15 ◽  
Author(s):  
Caibing Xu ◽  
Yalan Tang ◽  
Wenjing Hu ◽  
Rui Tian ◽  
Yuntao Jia ◽  
...  
Keyword(s):  
Inclusion Complex ◽  
Sulfobutyl Ether

An Assessment of Olmesartan Medoxomil Tablet by Inclusion Complex Technique

2021 ◽  
pp. 193-197
Author(s):  
Deepak Sarangi ◽  
Subhashree Mallick ◽  
Anjum Ara ◽  
Sanjeeb Kumar Sahoo ◽  
Rabinarayan Rana
Keyword(s):  
Inclusion Complex ◽  
Water Solubility ◽  
Olmesartan Medoxomil ◽  
Complexing Agents ◽  
Complexing Agent ◽  
Angiotensin Ii Receptor ◽  
Current Effort ◽  
Ir Studies ◽  
Beta Cyclodextrin ◽  
Ft Ir

Olmesartan Medoxomil is an AT1 subtype selected angiotensin-II receptor antagonist approved for the treatment of hypertension. It has low water solubility, so the current effort is being made to enhance the solubility of the Olmesartan by inclusion complex and to incorporate them into tablets by direct compression. Complexing agent like Beta cyclodextrin and polyvinyalpyrrolidone has been used for complexation method. FT-IR studies have shown that there is no link between drugs and complexing agents. Among all methods, the inclusion complex (OLBCD 3) containing the drug: Beta cyclodextrin in a 1: 3 ratio showed rapid drug release (87.41% within 30 minutes) and post compression parameters are within limits. All the values obtained from pre compression and post compression parameters meets the legal requirements for tablets. Stability studies of batch no OLBCD 3 shows no significant change. Therefore, it can be concluded that the structure was stable.

scholarly journals Inclusion complex of acetohexamide with .BETA.-cyclodextrin and its hypoglycemic activity in rabbit.

1979 ◽  
Vol 27 (2) ◽  
pp. 398-402 ◽  
Author(s):  
KANETO UEKAMA ◽  
NAOKI MATSUO ◽  
FUMITOSHI HIRAYAMA ◽  
TATSUYA YAMAGUCHI ◽  
YORISHIGE IMAMURA ◽  
...  
Keyword(s):  
Inclusion Complex ◽  
Hypoglycemic Activity ◽  
Beta Cyclodextrin
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