scholarly journals Short-Time Changes of Intraocular Pressure and Biomechanics of the Anterior Segment of the Eye during Water Drinking Test in Patients with XEN GelStent

2021 ◽  
Vol 11 (1) ◽  
pp. 175
Author(s):  
Joanna Przeździecka-Dołyk ◽  
Ewa Wałek ◽  
Agnieszka Jóźwik ◽  
Iwona Helemejko ◽  
Magdalena Asejczyk-Widlicka ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Anterior Segment ◽  
Outcome Evaluation ◽  
Control Group ◽  
Substantial Impact ◽  
Water Loading ◽  
Water Drinking ◽  
Compensation Mechanisms ◽  
Drinking Test ◽  
Water Drinking Test

Purpose: Little is known about short-term changes in intraocular pressure (IOP) following minimally invasive glaucoma surgeries, such as post-XEN GelStent implantation. Although the importance of corneal biomechanics in glaucoma diagnostics has been reported, little work has been conducted on postoperative description of changes when the structure of the anterior segment is altered. The aim of presented study was to evaluate the changes in the biomechanical parameters of the anterior segment of the post-XEN GelStent implantation eyes. Patients and Methods: This investigator-initiated, open-label, prospective, single-center study recruited patients. Patients with primary open-angle glaucoma (POAG) after XEN GelStent implantation versus matched POAG controls (considered as control group/CG) treated pharmacologically were screened. Water loading was conducted using 10 mL of water per kilogram of body weight for ≤5 min. Goldmann applanation tonometry (GAT), corneal hysteresis (CH), and corneal resistance factor (CRF) were performed before water loading and after every 15 min up to 1 h. Results: The water drinking test (WDT) was positive in 3.7% (1 out of 27) of patients in the post-XEN group compared with 22.7% (5 out of 22) of patients in the control group (CG; p < 0.05). Mean fluctuations in GAT during the WDT were higher in the CG group (3.6 ± 2.5 mmHg vs. 2.9 ± 1.3 mmHg, p < 0.001). CRF and CH changed significantly only in the post-XEN group. The mean peak of CH and CRF occurred at 15 and 30 min of the test in the post-XEN group (p = 0.001). Conclusion: WDT is important to assess the ability of compensation mechanisms to reduce fluctuations in IOP after water upload. The relationship between biomechanics of the anterior segment and glaucoma may have substantial impact on surgical outcome evaluation.

Evaluation of daily changes of Intraocular pressure in glaucomatous patients with modified diurnal tension curve versus water drinking test

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Eman Sayed Ahmed ◽  
Mohammed Adel Abdelshafik ◽  
Momen Mahmoud Hamdi ◽  
Noha Mohsen Mahmoud
Keyword(s):  
Intraocular Pressure ◽  
Open Angle Glaucoma ◽  
Control Group ◽  
Case Group ◽  
Provocative Test ◽  
Water Drinking ◽  
Drinking Test ◽  
The Mean ◽  
Tension Curve ◽  
Water Drinking Test

Abstract Background Glaucoma is a chronic optic neuropathy characterized by the excavation of the optic disc due to atrophy of the retinal ganglion cells. A progression of such atrophy leads to reduction of the visual field and eventually to the loss of sight at the end-stage of the disease, Glaucoma is the second leading cause of blindness worldwide Objectives To study the correlation between intraocular pressure (IOP) fluctuation during water drinking test (WDT) and the IOP fluctuation of modified diurnal tension curve (mDTC) in glaucomatous eyes Patients and Methods Fifty participants (24 males and 26 females) were recruited in this prospective study; forty participants with known Primary Open Angle Glaucoma and the other ten participants with non- glaucomatous healthy eyes which served as control. Patients attending the outpatient clinic at Al-Demerdash Hospital and Cairo Fatemic Hospital from October 2018 to March 2019 were prospectively recruited. Four IOP measurements were taken at 8:00 am, 12:00 pm, 4:00 pm and 8:00 pm which represented the mDTC, while WDT was represented by a single measurement of IOP before ingestion of one liter of water over five minutes, followed by three IOP measurements after ingestion of this amount of water at thirty minute intervals. Results Distribution of the studied participants as regards Age and sex: 50 participants were included in the this study. 40 presented the case group (20 males and 20 females) and the mean age of the case group was 54.7 years, 10 presented the control group(4 males and 6 females) and the mean age of the control group was 51.2years. 59% of participants had a peak IOP at 8:00 am, while 10% had a peak IOP at 12:00 pm, 6% at 4:00 pm and 25% of the participants had IOP peak at 8:00 pm during the mDTC. In the WDT, 96% of the participants had a peak IOP after 30 minutes of ingesting one liter of water, while 4% had a peak IOP after 60 minutes. None of the participants had IOP peak after 90 minutes of ingesting one liter of water.. The IOP fluctuations detected during the WDT were significantly correlated to fluctuations observed during the mDTC. Conclusion The data of this study suggested that WDT can be used as a useful provocative test for the detection of the diurnal IOP peaks and fluctuation observed in the glaucoma patients.

scholarly journals Correlation between central corneal thickness and intraocular pressure peak and fluctuation during the water drinking test in glaucoma patients

Clinics ◽  
2010 ◽  
Vol 65 (10) ◽  
pp. 967-970 ◽  
Author(s):  
Rafael Lacerda Furlanetto ◽  
Antonio Carlos Facio Jr ◽  
Marcelo Hatanaka ◽  
Remo Susanna Junior
Keyword(s):  
Intraocular Pressure ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Water Drinking ◽  
Pressure Peak ◽  
Drinking Test ◽  
Water Drinking Test

Rise of intraocular pressure in a caffeine testversusthe water drinking test in patients with glaucoma

2013 ◽  
Vol 42 (5) ◽  
pp. 427-432 ◽  
Author(s):  
Tuan Tran ◽  
Nuwan Niyadurupola ◽  
Jeremy O'Connor ◽  
Ghee Soon Ang ◽  
Jonathan Crowston ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Water Drinking ◽  
Drinking Test ◽  
Water Drinking Test

scholarly journals Intraocular pressure and corneal biomechanical changes after water-drinking test in glaucoma patients

2021 ◽  
Vol 33 (4) ◽  
pp. 394
Author(s):  
Farideh Sharifipour ◽  
Mohammad Malekahmadi ◽  
Mehdi Azimi ◽  
Bahman Cheraghian
Keyword(s):  
Intraocular Pressure ◽  
Water Drinking ◽  
Biomechanical Changes ◽  
Drinking Test ◽  
Water Drinking Test

scholarly journals Evaluation of Intraocular Pressure After Water Drinking Test in Patients with Unilateral Hemifacial Spasm

2020 ◽  
Vol Volume 14 ◽  
pp. 1675-1680
Author(s):  
Jin Rong Low ◽  
Chee Wai Wong ◽  
Jing Liang Loo ◽  
Dan Milea ◽  
Shamira A Perera ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Hemifacial Spasm ◽  
Water Drinking ◽  
Drinking Test ◽  
Water Drinking Test

Comparison of Intraocular Pressure Changes During the Water Drinking Test Between Different Fluid Volumes in Patients With Primary Open-angle Glaucoma

2018 ◽  
Vol 27 (11) ◽  
pp. 950-956 ◽  
Author(s):  
Carolina N. Susanna ◽  
Remo Susanna ◽  
Marcelo Hatanaka ◽  
Bianca N. Susanna ◽  
Fernanda N. Susanna ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Water Drinking ◽  
Drinking Test ◽  
Pressure Changes ◽  
Water Drinking Test

Comparison between provocative test-based and long-term intraocular pressure parameters in patients with stable open-angle glaucoma

2020 ◽  
pp. 112067212091133
Author(s):  
Izabela Almeida ◽  
Ana Luiza B Scoralick ◽  
Diego T Dias ◽  
Michele Ushida ◽  
Syril Dorairaj ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Provocative Test ◽  
Water Drinking ◽  
Medical Regimen ◽  
Pressure Peak ◽  
Drinking Test ◽  
Water Drinking Test

Purpose: To compare provocative test-based and long-term intraocular pressure variation parameters in patients with stable open-angle glaucoma. Methods: A prospective observational study was carried out in which stable open-angle glaucoma patients (⩾3 years of follow-up without any changes on current medical regimen) were consecutively enrolled. All patients were submitted to a water-drinking test. Long-term intraocular pressure parameters were obtained from isolated intraocular pressure measurements from each visit (⩾5 visits). We investigated the correlation and agreement between the following water-drinking test and long-term intraocular pressure parameters: mean, peak, and fluctuation. In addition, the percentage of eyes with significant intraocular pressure peaks during the water-drinking test (defined as a difference ⩾25% between water-drinking test intraocular pressure peak and mean long-term intraocular pressure) was assessed. Results: Sixty-three eyes from 63 open-angle glaucoma patients (mean age, 60.7 ± 11.8 years) were included. Mean and water-drinking test intraocular pressure peak correlated significantly with mean ( r = 0.67) and maximum long-term intraocular pressure ( r = 0.52), respectively ( p < 0.01). The correlation between water-drinking test intraocular pressure fluctuation and long-term intraocular pressure fluctuation was not significant ( p = 0.45). Limits of agreement from Bland–Altman plots exceeded the maximum allowed difference between methods (3 mm Hg) for all the intraocular pressure parameters analyzed, suggesting poor agreement between water-drinking test–derived and long-term intraocular pressure values. Overall, significant water-drinking test intraocular pressure peaks were observed in 39.7% of these eyes with stable open-angle glaucoma. Conclusion: Although some water-drinking test–based and long-term intraocular pressure parameters correlate significantly, water-drinking test results may not reflect the long-term intraocular pressure profile of stable open-angle glaucoma patients, as their agreement is poor. Many of these patients may experience significant water-drinking test intraocular pressure peaks, despite long-standing stable disease and unchanged medical regimen.

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