Comparison of Intraocular Pressure Changes During the Water Drinking Test Between Different Fluid Volumes in Patients With Primary Open-angle Glaucoma

2018 ◽  
Vol 27 (11) ◽  
pp. 950-956 ◽  
Author(s):  
Carolina N. Susanna ◽  
Remo Susanna ◽  
Marcelo Hatanaka ◽  
Bianca N. Susanna ◽  
Fernanda N. Susanna ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Water Drinking ◽  
Drinking Test ◽  
Pressure Changes ◽  
Water Drinking Test

Comparison between provocative test-based and long-term intraocular pressure parameters in patients with stable open-angle glaucoma

2020 ◽  
pp. 112067212091133
Author(s):  
Izabela Almeida ◽  
Ana Luiza B Scoralick ◽  
Diego T Dias ◽  
Michele Ushida ◽  
Syril Dorairaj ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Provocative Test ◽  
Water Drinking ◽  
Medical Regimen ◽  
Pressure Peak ◽  
Drinking Test ◽  
Water Drinking Test

Purpose: To compare provocative test-based and long-term intraocular pressure variation parameters in patients with stable open-angle glaucoma. Methods: A prospective observational study was carried out in which stable open-angle glaucoma patients (⩾3 years of follow-up without any changes on current medical regimen) were consecutively enrolled. All patients were submitted to a water-drinking test. Long-term intraocular pressure parameters were obtained from isolated intraocular pressure measurements from each visit (⩾5 visits). We investigated the correlation and agreement between the following water-drinking test and long-term intraocular pressure parameters: mean, peak, and fluctuation. In addition, the percentage of eyes with significant intraocular pressure peaks during the water-drinking test (defined as a difference ⩾25% between water-drinking test intraocular pressure peak and mean long-term intraocular pressure) was assessed. Results: Sixty-three eyes from 63 open-angle glaucoma patients (mean age, 60.7 ± 11.8 years) were included. Mean and water-drinking test intraocular pressure peak correlated significantly with mean ( r = 0.67) and maximum long-term intraocular pressure ( r = 0.52), respectively ( p < 0.01). The correlation between water-drinking test intraocular pressure fluctuation and long-term intraocular pressure fluctuation was not significant ( p = 0.45). Limits of agreement from Bland–Altman plots exceeded the maximum allowed difference between methods (3 mm Hg) for all the intraocular pressure parameters analyzed, suggesting poor agreement between water-drinking test–derived and long-term intraocular pressure values. Overall, significant water-drinking test intraocular pressure peaks were observed in 39.7% of these eyes with stable open-angle glaucoma. Conclusion: Although some water-drinking test–based and long-term intraocular pressure parameters correlate significantly, water-drinking test results may not reflect the long-term intraocular pressure profile of stable open-angle glaucoma patients, as their agreement is poor. Many of these patients may experience significant water-drinking test intraocular pressure peaks, despite long-standing stable disease and unchanged medical regimen.

Water-Drinking Test in Patients with Primary Open-Angle Glaucoma While Treated with Different Topical Medications

2005 ◽  
Vol 21 (3) ◽  
pp. 250-257 ◽  
Author(s):  
Michele Vetrugno ◽  
Dario Sisto ◽  
Tiziana Trabucco ◽  
Francesca Balducci ◽  
Nicola Delle Noci ◽  
...  
Keyword(s):  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Water Drinking ◽  
Drinking Test ◽  
Topical Medications ◽  
Water Drinking Test

Intraocular pressure changes following topical ocular hypotensive medications washout

2020 ◽  
pp. bjophthalmol-2019-315778
Author(s):  
Henrietta Ho ◽  
Arij Daas ◽  
Jason Ho ◽  
Pouya Alaghband ◽  
Elizabeth Angela Galvis ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Intraocular Pressure ◽  
Incomplete Data ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Steroid Treatment ◽  
Open Angle ◽  
The Mean ◽  
Active Inflammation ◽  
Pressure Changes

BackgroundTo review the changes in intraocular pressure (IOP) following topical hypotensive medications washout in patients with primary open angle glaucoma (POAG), ocular hypertension (OHT) and uveitic glaucoma (UG)/OHT.MethodsThe study included 120 patients with POAG, OHT and UG recruited from prospective clinical trials between February 2013 and July 2017. We excluded 20 eyes with IOP of ≤21 mm Hg, 11 eyes with previous incisional surgery and 17 eyes with incomplete data. UG eyes with active inflammation and on steroid treatment were excluded. Participants underwent a 1-month washout period from topical ocular hypotensive medications before IOP phasing. Comparisons were made between pre/post-washout IOP, and highest-recorded (peak) and post-washout IOP.ResultsA total of 110 eyes with POAG, 33 eyes with OHT and 43 eyes with UG were included for analysis. The mean pre-washout IOP was 18.1±3.3 mm Hg in POAG, 18.8±3.3 mm Hg in OHT and 17.9±8.8 mm Hg in UG; the mean post-washout IOP was 26.6±4.8 mm Hg, 26.4±3.9 mm Hg, 23.1±10.1 mm Hg in POAG, OHT and UG, respectively. The mean increase in IOP after washout was significantly lower in UG compared with POAG and OHT eyes (p=0.01). The percentage of eyes with post-washout IOP <22 mm Hg was 12.7% in POAG, 6.1% in OHT and 51.2% in UG.ConclusionActive inflammation and steroid treatment contributes to elevated IOP in uveitis. Therefore, IOP may revert to normal once inflammation subsides. We recommend ocular hypotensive treatment washout to be considered in UG eyes that have IOP under control in the absence of recurrence of uveitis.

A Comparative Study of the Water Drinking Test in Eyes With Open-Angle Glaucoma and Prior Trabeculectomy or Tube Shunt

2017 ◽  
Vol 26 (2) ◽  
pp. 119-125 ◽  
Author(s):  
Patricia Martinez ◽  
Valerie Trubnik ◽  
Benjamin E. Leiby ◽  
Sarah E. Hegarty ◽  
Reza Razeghinejad ◽  
...  
Keyword(s):  
Comparative Study ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Water Drinking ◽  
Drinking Test ◽  
Tube Shunt ◽  
Water Drinking Test

scholarly journals Water drinking test: Intraocular pressure changes after tube surgery and trabeculectomy

2017 ◽  
Vol 12 (4) ◽  
pp. 390 ◽  
Author(s):  
MohammadHossein Nowroozzadeh ◽  
MohammadReza Razeghinejad ◽  
Zahra Tajbakhsh ◽  
Masoumeh Masoumpour
Keyword(s):  
Intraocular Pressure ◽  
Water Drinking ◽  
Drinking Test ◽  
Pressure Changes ◽  
Water Drinking Test
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