Faculty Opinions recommendation of 8-year follow-up of patients treated for borderline personality disorder: mentalization-based treatment versus treatment as usual.

Author(s):  
Ruth Lanius ◽  
Camelia Garofeanu
2010 ◽  
Vol 197 (6) ◽  
pp. 456-462 ◽  
Author(s):  
Kate M. Davidson ◽  
Peter Tyrer ◽  
John Norrie ◽  
Stephen J. Palmer ◽  
Helen Tyrer

BackgroundLonger-term follow-up of patients with borderline personality disorder have found favourable clinical outcomes, with long-term reduction in symptoms and diagnosis.AimsWe examined the 6-year outcome of patients with borderline personality disorder who were randomised to 1 year of cognitive–behavioural therapy for personality disorders (CBT–PD) or treatment as usual (TAU) in the BOSCOT trial, in three centres across the UK (trial registration: ISRCTN86177428).MethodIn total, 106 participants met criteria for borderline personality disorder in the original trial. Patients were interviewed at follow-up by research assistants masked to the patient's original treatment group, CBT–PD or TAU, using the same measures as in the original randomised trial. Statistical analyses of data for the group as a whole are based on generalised linear models with repeated measures analysis of variance type models to examine group differences.ResultsFollow-up data were obtained for 82% of patients at 6 years. Over half the patients meeting criteria for borderline personality disorder at entry into the study no longer did so 6 years later. The gains of CBT–PD over TAU in reduction of suicidal behaviour seen after 1-year follow-up were maintained. Length of hospitalisation and cost of services were lower in the CBT–PD group compared with the TAU group.ConclusionsAlthough the use of CBT–PD did not demonstrate a statistically significant cost-effective advantage, the findings indicate the potential for continued long-term cost-offsets that accrue following the initial provision of 1 year of CBT–PD. However, the quality of life and affective disturbance remained poor.


2018 ◽  
Vol 48 (15) ◽  
pp. 2522-2529 ◽  
Author(s):  
Elisabeth M. P. Laurenssen ◽  
Patrick Luyten ◽  
Martijn J. Kikkert ◽  
Dieuwertje Westra ◽  
Jaap Peen ◽  
...  

AbstractBackgroundDay hospital mentalization-based treatment (MBT-DH) is a promising treatment for borderline personality disorder (BPD) but its evidence base is still limited. This multi-site randomized trial compared the efficacy of MBT-DH delivered by a newly set-up service v. specialist treatment as usual (S-TAU) tailored to the individual needs of patients, and offered by a well-established treatment service.MethodsTwo mental healthcare institutes in The Netherlands participated in the study. Patients who met DSM-IV criteria for BPD and had a score of ⩾20 on the borderline personality disorder severity index (BPDSI) were randomly allocated to MBT-DH (N = 54) or S-TAU (N = 41). The primary outcome variable was the total score on the BPDSI. Secondary outcome variables included symptom severity, quality of life, and interpersonal functioning. Data were collected at baseline and every 6 months until 18-month follow-up, and were analyzed using multilevel analyses based on intention-to-treat principles.ResultsBoth treatments were associated with significant improvements in all outcome variables. MBT-DH was not superior to S-TAU on any outcome variable. MBT-DH was associated with higher acceptability in BPD patients compared v. S-TAU, reflected in significantly higher early drop-out rates in S-TAU (34%) v. MBT-DH (9%).ConclusionsMBT-DH delivered by a newly set-up service is as effective as specialist TAU in The Netherlands in the treatment of BPD at 18-month follow-up. Further research is needed to investigate treatment outcomes in the longer term and the cost-effectiveness of these treatments.


Author(s):  
Noha F. M. Fnoon ◽  
Mai A. Eissa ◽  
Ehab E. Ramadan ◽  
Hossam E. El-Sawy ◽  
Ahmed M. A. Abd El-Karim

Background: Researchers have proved the role of dialectical behavior therapy (DBT) in improving emotion regulation skills in patients with borderline personality disorder (BPD). Further researches for its effect in different cultures was needed. The current study aimed to examine the effectiveness of DBT relative to treatment as usual “TAU” in improving emotional regulation in BPD patients of the delta region of Egypt. Subjects and Methods: We conducted a prospective, comparative, non-randomized study. Eligible patients were assigned at their convenience or according to the immediate availability of treatment slots to a comprehensive DBT program integrating DBT skills into skills training schedule or treatment as usual (TAU). Patients were assessed at baseline, and follow up assessment at 4, 8, 12, and 16 months was done using the Arabic version of, Difficulties in Emotion Regulation Scale (DERS), Results: DBT patients showed better and lower scores of emotion regulation and distress tolerance scales in comparison to TAU. Overall, these positive outcomes were maintained in follow-up for four months post-treatment year. Conclusions: We provide the superior efficacy of DBT in improving emotion regulation in delta region's patients with BPD in comparison to TAU.


2019 ◽  
pp. 1-11
Author(s):  
Antonio Andreoli ◽  
Yvonne Burnand ◽  
Laura Frambati ◽  
Donna Manning ◽  
Allen Frances

The authors present the results from a 3-year follow-up among 170 patients who had participated in the original randomized study, which consisted of three treatment conditions: (a) 3-month abandonment psychotherapy (AP) delivered by certified psychotherapists, (b) AP delivered by nurses, and (c) treatment as usual in a psychiatric crisis center. All subjects were recruited at the emergency room after a suicide attempt and met diagnostic criteria for borderline personality disorder and major depression. Psychotic symptoms, bipolar disorder, and mental retardation were exclusion criteria. At 3-year follow-up, 134 (78.8%) subjects had blind, reliable assessment by clinical psychologists. The intent-to-treat analysis indicated that those patients who had received AP during acute treatment had better global functioning, improved work adjustment, and less unemployment/disability at 3-year follow-up. No differences were found as a function of type of therapist delivering AP. The data confirm that short-term AP gains in psychosocial functioning are sustained over the longer term.


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