Faculty Opinions recommendation of Integrating mechanistic and polymorphism data to characterize human genetic susceptibility for environmental chemical risk assessment in the 21st century.

Author(s):  
Michael Cunningham
2018 ◽  
Vol 20 (1) ◽  
pp. 58-71 ◽  
Author(s):  
Antonio Di Guardo ◽  
Todd Gouin ◽  
Matthew MacLeod ◽  
Martin Scheringer

Twenty-five years of progress in modeling the environmental fate and exposure of organic contaminants is reviewed, and a strategy for more rapidly adopting scientific progress into regulatory models is proposed.


2019 ◽  
Vol 15 ◽  
pp. 8-17 ◽  
Author(s):  
Hanna K.L. Johansson ◽  
Julie Boberg ◽  
Marianne Dybdahl ◽  
Marta Axelstad ◽  
Anne Marie Vinggaard

2017 ◽  
Author(s):  
Mikael B Gustavsson ◽  
Jörgen Magnér ◽  
Bethanie Carney Almroth ◽  
Martin K Eriksson ◽  
Joachim Sturve ◽  
...  

Chemical pollution was monitored and assessed along the Swedish west coast. 62 of 172 analyzed organic chemicals were detected in the water phase of at least one of five monitored sites. A Concentration Addition based screening-level risk assessment indicates that all sites are put at risk from chemical contamination, with total risk quotients between 2 and 9. Only at one site did none of the individual chemicals exceeded its individual environmental threshold (PNEC, EQS). The monitoring data thus demonstrate a widespread blanket of diffuse pollution, with no clear trends amongst sites. Further issues critical for the environmental chemical risk assessment include the challenges to achieve sufficiently low levels of detection especially for hormones and cybermethrin (a pyrethroid insecticide), the appropriate consideration of non-detects and the limited availability of reliable PNECs and EQS values.


Author(s):  
R. Kakko ◽  
H. Länsipuro ◽  
A. Lancia ◽  
I. C. Ziomas ◽  
P. M. Foster

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