Faculty Opinions recommendation of Myocardial ischaemia in patients with coronary endothelial dysfunction: insights from body surface ECG mapping and implications for invasive evaluation of chronic chest pain.

2011 ◽  
Author(s):  
Juan-Carlos Kaski ◽  
Peter Ong
Keyword(s):  
Chest Pain ◽  
Endothelial Dysfunction ◽  
Body Surface ◽  
Myocardial Ischaemia ◽  
Surface Ecg ◽  
Invasive Evaluation ◽  
Coronary Endothelial Dysfunction

Prognostic Impact of Coronary Endothelial Dysfunction on Long-Term Adverse Outcome in Patients with Chest Pain and Non-Obstructive Coronary Artery Disease

2013 ◽  
Vol 23 (1) ◽  
pp. 114-119
Author(s):  
Dalia Jarašūnienė ◽  
Ernesta Susekaitė ◽  
Nerijus Klimas
Keyword(s):  
Chest Pain ◽  
Endothelial Dysfunction ◽  
Endothelial Function ◽  
Adverse Outcome ◽  
Obstructive Coronary Artery Disease ◽  
Coronary Intervention ◽  
Cardiovascular Death ◽  
Prognostic Impact ◽  
Coronary Endothelial Dysfunction

Coronary endothelial dysfunction is known to be related with adverse cardiovascular outcome. We obtained a long-term follow-up of patients without significant coronary atherosclerosis, complaining of chest pain, in whom intra-coronary acetylene testing was performed in order to assess endothelial function. The study included 41 patient (35 with endothelial dysfunction, 6 with preserved endothelial function). Events considered as adverse outcome were cardiovascular death, acute myocardium-dial infarction, unstable angina pectoris, percutaneous coronary intervention, coronary-aortic by-pass grafting, ischemic stroke and peripheral artery re-vascularization. A high cardiovascular event rate was observed in patients with and without endothelial dysfunction, 34,3% and 50% respectively. Adverse outcome was related not only to endothelial dysfunction but also to traditional cardiovascular risk factors. Thus, evaluation of endothelial function or its determinants seems to be helpful in identifying a subgroup of patients at high risk.

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