ABSTRACT
Neal Hammer works in the field of bacterial pathogenesis, metabolism, and antibiotic resistance. In this mSphere of Influence article, he reflects on how “Gut inflammation provides a respiratory electron acceptor for Salmonella” by Winter and colleagues (S. E. Winter, P. Thiennimitr, M. G. Winter, B. P. Butler, et al., Nature 467:426–429, 2010, https://doi.org/10.1038/nature09415) made an impact on him by demonstrating that Salmonella enterica serotype Typhimurium metabolism is uniquely suited to exploit the chemical by-products that result from the host’s inflammatory response.
mSphere of Influence: a Controlled Burn—Pathogen Manipulation of the Dynamic Chemistry That Results from Inflammation