Faculty Opinions recommendation of Sentinel lymph node biopsy in Merkel cell carcinoma: a 15-year institutional experience and statistical analysis of 721 reported cases.

Author(s):  
Giuseppe Argenziano ◽  
Elvira Moscarella
2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Eric P. Arruda ◽  
Kevin M. Higgins

Merkel cell carcinoma (MCC) is a rare and typically aggressive form of skin cancer. It most commonly affects the elderly and has a predilection for the sun-exposed skin of the head and neck region. Other etiological factors include immune suppression, organ transplantation, and polyoma virus infection. MCC has a propensity to spread to regional lymphatics with a high locoregional recurrence rate. Since its discovery in 1972, treatment paradigms have shifted, with no consensus on optimal management strategies. Currently, standard of care includes surgical intervention to the primary and locoregional site with adjuvant radiotherapy for high-risk disease. In this paper, we discuss the history, pathology, and epidemiology of this rare disease with a focus on the evidentiary basis of treatment protocols. The use of sentinel lymph node biopsy as a management option will be the focus of this paper.


2020 ◽  
Vol 231 (4) ◽  
pp. S286
Author(s):  
Michael J. Minarich ◽  
Elizabeth A. Handorf ◽  
Leah G. Stockton ◽  
Maitham A. Moslim ◽  
Stephanie H. Greco ◽  
...  

2008 ◽  
Vol 15 (9) ◽  
pp. 2509-2518 ◽  
Author(s):  
Ross E. Warner ◽  
Michael J. Quinn ◽  
George Hruby ◽  
Richard A. Scolyer ◽  
Roger F. Uren ◽  
...  

2013 ◽  
Vol 21 (5) ◽  
pp. 1624-1630 ◽  
Author(s):  
Swapnil D. Kachare ◽  
Jan H. Wong ◽  
Nasreen A. Vohra ◽  
Emmanuel E. Zervos ◽  
Timothy L. Fitzgerald

2005 ◽  
Vol 131 (7) ◽  
pp. 610 ◽  
Author(s):  
Cecelia E. Schmalbach ◽  
Lori Lowe ◽  
Theodoros N. Teknos ◽  
Timothy M. Johnson ◽  
Carol R. Bradford

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