Abstract. Labour conditions of workers contacting with fibrogenic silicate dust in isolators’ production were studied. Additional examination included determination of the degree of endothelial disfunction, apoptosis and systemic inflammation. Besides the effect of Ethylmethylhydroxypyridine succinate on these parameters and the lipid profile was evaluated. Atherogenic changes of the lipid profile, moderate endothelial disfunction (level of circulating endotheliocytes is 6,04±1,97*104/l), slight tension of apoptosis (TNF-α 8,11±6,67 pg/ml) and activation of systemic inflammation (C-RP 8,1±4,5 mg/l) were found. Application of Ethylmethylhydroxypyridine succinate led to the partial correction of dyslipidemia and endothelial disfunction without the significant effect on other researching laboratory parameters; significant improvement of respiratory function was noted.
AVALIAÇÃO DA FLEXIBILIZAÇÃO DO JEJUM PARA DETERMINAÇÃO LABORATORIAL DO PERFIL LIPÍDICO / ASSESSMENT OF FLEXIBILIZATION OF FASTING FOR LABORATORY DETERMINATION OF THE LIPID PROFILE
