АКТУАЛЬНЫЕ АСПЕКТЫ ПРИМЕНЕНИЯ ПИМЕКРОЛИМУСА В КЛИНИЧЕСКОЙ ПРАКТИКЕ

10.36691/raj.2019.1-1.53226 ◽

2019 ◽

Author(s):

A.N. Lvov

Keyword(s):

В статье приводятся современные данные по патогенетической концепции нейрогенного воспаления при иммуноопосредованных дерматозах. На основании анализа литературы и собственного опыта освещены основные аспекты применения пимекролимуса при атопическом дерматите и других заболеваниях кожи.Modern aspects of patogenetic conception of neurogenic inflammation in immune associated dermatoses are presented in the article. On the basis of literature data and own experience important aspects of pimecrolimus application in atopic dermatitis and other dermatoses are reviewed.

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Neuroimmune mechanisms of pruritus in atopic dermatitis

Medical alphabet ◽

10.33667/2078-5631-2021-41-12-16 ◽

2022 ◽

pp. 12-16

Author(s):

Y. A. Kandrashkina ◽

E. A. Orlova ◽

A. A. Pribytkov

Keyword(s):

Quality Of Life ◽

Atopic Dermatitis ◽

Skin Disease ◽

Neurogenic Inflammation ◽

New Methods ◽

Neuroimmune Interactions ◽

High Prevalence ◽

Depth Study

Atopic dermatitis is a chronic hereditary recurrent skin disease. One of the most pronounced symptoms of this dermatosis is itchy skin. Pruritus accompanies atopic dermatitis in more than 80% of cases. This review presents modern data on the mechanisms of pruritus formation in atopic dermatitis. The issues of etiological factors, neuroimmune interactions, peculiarities of skin dysfunction, as well as the role of stress are considered. The relevance of studying the topic is due to the high prevalence of atopic dermatitis among the population, a decrease in the quality of life and the lack of effective therapy. Analysis of the literature indicates the need for a comprehensive assessment of the pathogenetic mechanisms of the development of pruritus in atopic dermatitis. A more in-depth study of the mechanisms of neurogenic inflammation in atopic dermatitis will contribute to the development of new methods of diagnosis and treatment.

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Current aspects of pimecrolimus application in clinical practice

Rossiiskii Allergologicheskii ZHurnal ◽

10.36691/rja28 ◽

2019 ◽

Vol 16 (1) ◽

pp. 65-70

Author(s):

A N Lvov

Keyword(s):

Atopic Dermatitis ◽

Clinical Practice ◽

Neurogenic Inflammation

Modern aspects of patogenetic conception of neurogenic inflammation in immune associated dermatoses are presented in the article. On the basis of literature data and own experience important aspects of pimecrolimus application in atopic dermatitis and other dermatoses are reviewed.

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