scholarly journals Association of Hyperhomocysteinemia and Adverse Postoperative Outcomes of on-Pump Primary Isolated Coronary Artery Bypass Grafting Surgery among Postmenopausal Women

2019 ◽  
Vol 4 (1) ◽  
Author(s):  
Saber Ahmed ◽  
Fathy Ayat ◽  
Nasr Sherif
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Postmenopausal Women ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Postoperative Outcomes ◽  
Bypass Grafting ◽  
Artery Bypass Grafting

Effect of gender on postoperative outcomes and hospital stays after coronary artery bypass grafting

1999 ◽  
Vol 67 (4) ◽  
pp. 1097-1103 ◽  
Author(s):  
Gabriel S Aldea ◽  
Jennifer M Gaudiani ◽  
Oz M Shapira ◽  
Alice K Jacobs ◽  
Janice Weinberg ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Postoperative Outcomes ◽  
Bypass Grafting ◽  
Artery Bypass Grafting ◽  
Hospital Stays

scholarly journals Are the Early Postoperative Outcomes of Coronary Artery Bypass Grafting Surgery in Elderly Women Worse Compared to Men's?

2017 ◽  
Author(s):  
Ahmet Yüksel ◽  
Irem Iris Kan ◽  
Atıf Yolgösteren ◽  
Yusuf Velioğlu ◽  
Mustafa Çagdaş Çayır ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Elderly Women ◽  
Artery Bypass ◽  
Postoperative Outcomes ◽  
Bypass Grafting ◽  
Artery Bypass Grafting ◽  
Surgery In Elderly

scholarly journals Role of Preexisting Proarrhythmic Atrial Remodeling in Post-Coronary Artery Bypass Grafting Atrial Fibrillation

2021 ◽  
Vol 31 (3) ◽  
pp. 597-607
Author(s):  
Alkora Ioana BALAN ◽  
◽  
Irina PINTILIE ◽  
Cristina SOMKEREKI ◽  
Marcel PERIAN ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
P Wave ◽  
Postoperative Outcomes ◽  
Atrial Remodeling ◽  
Bypass Grafting ◽  
Artery Bypass Grafting ◽  
Increased Risk

Introduction: Due to its deleterious effects, early identifi cation of patients at risk of postoperative AF (POAF) is of critical importance. Preexisting proarrhythmic atrial remodeling could contribute to this increased risk. Therefore, we aimed to evaluate the presence of preexisting proarrhythmic atrial remodeling and its impact on POAF occurrence in patients undergoing coronary artery bypass grafting (CABG). Methods: Data regarding atrial structural (atrial size and histology), electrical (P-wave and atrial action potential parameters, mRNA expression of several AF-related genes), and autonomic (heart rate variability parameters) proarrhythmic remodeling were compared between patients with (AF; n=11) and without (no-AF; n=19) POAF. Impact of POAF on postoperative outcomes was also evaluated. Results: No signifi cant difference was observed in atrial electrical parameters between the two groups (all p>0.05). However, compared with no-AF, AF patients had more important subepicardial adipose infi ltration (p=0.02) and higher markers of parasympathetic and sympathetic modulation (both p=0.03). Patients with POAF had longer hospital stay and more often presented postoperative renal dysfunction (both p=0.04). Conclusion: These fi ndings suggest that preexisting atrial structural (i.e., increased atrial subepicardial adiposity) and autonomic (i.e., sympatho-vagal coactivation) alterations could favor the occurrence of POAF. At its turn, POAF was associated with altered postoperative outcomes in CABG patients.

Effect of Sustained Use of Aspirin until the Time of Surgery on Outcomes following Coronary Artery Bypass Grafting: A Randomized Clinical Trial

2017 ◽  
Vol 66 (06) ◽  
pp. 442-451 ◽  
Author(s):  
Alireza Kamali ◽  
Yazdan Ghandi ◽  
Mehrzad Sharifi
Keyword(s):  
Clinical Trial ◽  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Postoperative Outcomes ◽  
Bypass Grafting ◽  
Artery Bypass Grafting ◽  
Group 2 ◽  
Group 1

Background The topic of aspirin (acetylsalicylic acid, ASA) use in coronary artery disease patients planned for coronary artery bypass grafting during perioperative period is among the most disputed issues in cardiac surgery. We designed a study to weigh the risks and benefits of continued ASA ingestion until the time of surgery. Methods In this randomized double-blind clinical trial, 206 consecutive patients scheduled for isolated coronary artery bypass surgery (CABG) were randomly stratified into two groups. In group 1 (104 cases), patients were given 80 mg ASA per day until the day of surgery. In group 2 (102 patients), ASA (80 mg per day) was stopped 4 days before the operation. Patients in these two groups were similar in terms of preoperative patient and procedural characteristics. ASA was resumed 24 hours after the surgery in all patients. Results The rates of bleeding and reexploration within 24 hours of surgery were significantly higher in group 1 (824.3 vs. 492.1 mL, p < 0.001 and 5.7% vs. 0, p = 0.0138, respectively). The amount of intra- and postoperative packed red blood cell (PRBC) transfusion was considerably greater in group 1 (mean: 1.83 vs. 0.71 units, p < 0.001). The rate of hospital mortality was similar (1.9% in both the groups, p = 0.98). Patients in group 1 had significantly longer mean hospital stay than patients in group 2 (8 vs. 5.1 days, p < 0.001). Again the time interval between weaning from heart–lung machine and closing the sternum was strikingly longer in group 1 (mean: 32.1 vs. 14.5 minutes, p < 0.001). The incidence of adverse postoperative outcomes such as myocardial infarction, stroke, and renal failure was not statistically different between the two groups. Conclusion Sustained ASA use until the day of surgery in patients planned for elective isolated CABG can result in excessive bleeding, increased rate of reexploration, and need for more PRBC transfusion without any proven beneficial effect on reducing unfavorable postoperative outcomes. Hence, we recommend discontinuing ASA between 3 and 5 days before non-urgent CABG while keeping it on in nonelective circumstances.

scholarly journals The Impact of Age on Outcomes of Coronary Artery Bypass Grafting

2020 ◽  
Author(s):  
anthony lemaire ◽  
Cassandra Soto ◽  
Lauren Salgueiro ◽  
Hirohisa Ikegami ◽  
Mark J. Russo ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Surgical Outcomes ◽  
Artery Bypass ◽  
Postoperative Outcomes ◽  
Age Difference ◽  
Bypass Grafting ◽  
Artery Bypass Grafting ◽  
The Impact

Abstract Objective As the population ages, increasing number of older patients are undergoing adult cardiac surgery. The purpose of the study is to assess the impact of age on postoperative outcomes in patients that undergo coronary artery bypass grafting (CABG).Methods Patients that are ≥70 years old who underwent CABG were selected from the Nationwide/National Inpatient Sample from 2010 to 2015 using ICD-9-CM diagnosis and procedure codes. The patients who were 70–79 years old were compared to patients aged 80–89 years old to determine if the age difference of the patients had an impact on surgical outcomes. In addition, a secondary endpoint is to compare surgical outcomes between the 2 genders of the patients 80-89 years old. The rates of postoperative complications, and mortality were compared.Results A total of 67,568 patients were identified who were ≥70 years old and underwent CABG. Compared to the Septuagenarians, the Octogenarians were more likely to develop cardiac complications (OR [odds ratio] =1.20, 95% CI [confidence interval] 1.12-1.23. They were also more likely to develop renal complications (P <0001), and respiratory complications (P <0001). The Octogenarians were also more likely to bleed postoperatively (P <0.0001) and have a higher mortality (P <0001). Furthermore, the female Octogenarians had a higher mortality (OR 1.25 95% CI 1.07–1.46) compared to males in the same age group.Conclusions The patients who were ≥80 – 89 years old had worse postoperative outcomes. The Octogenarians who were females had a higher mortality compared to their male counterparts.

scholarly journals The Effects of Aortic Clamping Strategy on Myocardial Protection and Early Postoperative Outcomes During Coronary Artery Bypass Grafting Operations

2021 ◽  
Vol 24 (2) ◽  
pp. E217-E222
Author(s):  
Cüneyt Eris ◽  
Burak Erdolu ◽  
Mesut Engin ◽  
Ahmet Kagan As ◽  
Yasemin Ustundag
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Myocardial Protection ◽  
Artery Bypass ◽  
Postoperative Outcomes ◽  
Bypass Grafting ◽  
Artery Bypass Grafting ◽  
Group 2 ◽  
Group 1

Background: The purpose of the present study was to compare the effects of two different clamping strategies for the construction of the proximal aortocoronary anastomoses on myocardial protection and postoperative outcomes during coronary artery bypass grafting (CABG) operations. Methods: In this retrospective study, we examined prospectively collected data of patients who underwent CABG for a 3-year period. Two hundred consecutive patients, who were diagnosed with triple vessel coronary artery disease (CAD), were selected and divided into two groups. In Group 1 (single clamp) (N = 100), venoaortic proximal anastomoses were performed using a single aortic cross-clamp, while in Group 2 (double clamp) (N = 100), proximal anastomoses were performed by using an aortic side clamp. Operative and postoperative outcomes of the patients were compared between the two groups. The serum levels of myocardial damage biomarkers, creatine phosphokinase-MB (CPK-MB), and high sensitive Troponin (hsTnI) results were measured preoperatively, intraoperatively, and postoperatively (6, 12, 24, and 48 hours). Results: Patient demographics and characteristics were similar between the two groups. In Group 1, cross-clamp duration time (65 min versus 49 min; P = .0001) was longer. However, perfusion time (91 min versus 85 min; P = .61) was similar between the two groups. In Group 2, postoperative CK-MB levels were significantly higher intraoperatively (P = .18), 6 hours (P = .22), 24 hours (P = .001), and 48 hours (P = .001) than in Group 1. HsTnI was only significantly higher in Group 2 versus Group 1 at 24 hours (P = .001) and 48 hours (P = .01) postoperatively. Time of intensive care unit stay, duration of extubation, and length of hospital stay were similar in both groups. Conclusion: The technique used for proximal anastomosis has a significant effect on perioperative results, especially on myocardial protection.

scholarly journals Investigation of Impact of Trinitroglycerin Conjugated Cardioplegia on Myocardial Protection of Patients With Coronary Artery Bypass Grafting

2020 ◽  
Author(s):  
Mohammad Hasan Nemati ◽  
Hasan Badie ◽  
Mansour Jannati
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Myocardial Protection ◽  
Artery Bypass ◽  
Postoperative Outcomes ◽  
Bypass Grafting ◽  
Medical Sciences ◽  
Artery Bypass Grafting ◽  
The Impact

Pharmacologic-conjugated-cardioplegia is one of the strategies against ischemia and reperfusion. The aim of this study was to investigate the impact of nitroglycerin on myocardial protection and postoperative outcomes. This was a case-control study performed on 91 patients undergoing coronary artery bypass grafting in Faghihi Hospital, Shiraz University of Medical Sciences. Patients were randomly divided into case and control groups. Trinitroglycerin Conjugated Cardioplegia on Myocardial Protection of Patients with Coronary Artery Bypass Grafting. As a result of nitroglycerin, the number of patients requiring inotrope administration was increased. No other significant alteration was observed between two groups in neither of ischemic features nor postoperative outcomes. In conclusion, nitroglycerin conjugated cardioplegia, with the condition of this study, demonstrated a negative inotrope requirement without improvement in myocardium protection. © 2019 Tehran University of Medical Sciences. All rights reserved.

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