scholarly journals Portal venous stent placement for treatment of portal hypertension caused by benign main portal vein stenosis

2005 ◽  
Vol 11 (21) ◽  
pp. 3315 ◽  
Author(s):  
Hong Shan
Keyword(s):  
Portal Hypertension ◽  
Portal Vein ◽  
Stent Placement ◽  
Main Portal Vein ◽  
Portal Vein Stenosis ◽  
Vein Stenosis

scholarly journals Percutaneous transhepatic metallic stent placement for the treatment of post-transplantation portal vein stenosis

2009 ◽  
Vol 150 (26) ◽  
pp. 1231-1234 ◽  
Author(s):  
Attila Doros ◽  
Balázs Nemes ◽  
Imre Fehérvári ◽  
Dénes Görög ◽  
Zsuzsa Gerlei ◽  
...  
Keyword(s):  
Portal Vein ◽  
Stent Placement ◽  
Metallic Stent ◽  
Post Transplantation ◽  
Portal Vein Stenosis ◽  
Vein Stenosis ◽  
Metallic Stent Placement

A májátültetés rutinszerűen, jó eredménnyel alkalmazott eljárás a végstádiumú májelégtelenség kezelésében. A transzplantáció után kialakuló éreredetű szövődmények közül a legritkább a májkapuér-szűkület. Ennek intervenciós radiológiai megoldását mutatjuk be három eset kapcsán. Célkitűzés: A portalis véna szűkületének sebészi kezelése kockázatos, különösen a korai poszttranszplantációs időszakban. Az intervenciós radiológiai beavatkozások általában kis megterheléssel, kevés szövődménnyel alkalmazhatók. Célunk bemutatni a percutan transhepaticus fémstentbehelyezés biztonságosságát, eredményességét. Módszer: Háromszázkilencvenhat májátültetés után összesen három esetben (0,07%) észleltük az anasztomózis korai beszűkülését. Ezekben az esetekben ultrahangvezérelt percutan transhepaticus venaportae-punkciót végeztünk vékony tűvel, majd koaxiális tágítókatétert alkalmazva stent behelyezésére alkalmas introducert vezettünk át a májszöveten. A szűk anasztomózisba nitinol (2 esetben), illetve acél (1 esetben) öntáguló fémstentet helyeztünk. Az introducer eltávolítása közben a parenchymás járatot egy alkalommal embolizációs spirállal, egyszer pedig sebészi szivacsrészecskékkel embolizáltuk. A harmadik esetben embolizáció nem történt. Eredmények: A kezelés mindhárom esetben sikeres volt. A beavatkozással kapcsolatban szövődményt nem észleltünk. Két esetben az indikációt jelentő hasi folyadék mennyiségének csökkenése, egy esetben a nyelőcső-varicositas visszafejlődése jelentette a klinikai kép javulását. Mindhárom esetben ultrahangos és komputeres rétegvizsgálat is igazolta a szűkületek sikeres kezelését. Két beteg a beavatkozás után 10, illetve 39 hónappal jól van. Egy beteget a beavatkozás után egy hónappal többszervi elégtelenség miatt elvesztettünk. Következtetés: A venaportae-anasztomózis szűkületeinek kezelésére a percutan transhepaticus kanülálás és öntáguló fémstent behelyezése biztonságosan és sikeresen alkalmazható.

scholarly journals Correction of extrahepatic portal hypertension in pediatric patient after liver transplantation

2017 ◽  
Vol 19 (1) ◽  
pp. 47-51
Author(s):  
A. R. Monakhov ◽  
B. L. Mironkov ◽  
T. A. Dzhanbekov ◽  
K. O. Semash ◽  
Kh. M. Khizroev ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Blood Flow ◽  
Portal Hypertension ◽  
Portal Vein ◽  
Pediatric Patient ◽  
Portal Blood Flow ◽  
Portal Blood ◽  
Positive Trend ◽  
Portal Vein Stenosis ◽  
Vein Stenosis

Introduction. Liver transplantation is a multi-component and complex type of operative treatment. Patients undergoing such a treatment sometimes are getting various complications. One of these complications is a portal hypertension associated with portal vein stenosis.Materials and methods. In 6 years after the left lateral section transplantation from living donor in a pediatric patient the signs of portal hypertension were observed. Stenosis of the portal vein was revealed. Due to this fact percutaneous transhepatic correction of portal vein stenosis was performed.Results. As a result of the correction of portal blood flow in the patient a positive trend was noted. According to the laboratory and instrumental methods of examination the graft had a normal function, portal blood flow was adequate. In order to control the stent patency Doppler ultrasound and MSCT of the abdominal cavity with intravenous bolus contrasting were performed. Due to these examinations the stent function was good, the rate of blood flow in the portal vein due to Doppler data has reached 80 cm/sec, and a decrease of the spleen size was noted.Conclusion. Diagnosis and timely detection of portal vein stenosis in patients after liver transplantation are very important for the preservation of graft function and for the prevention of portal hypertension. In order to do that, ultrasound Doppler fluorimetry examination needs to be performed to each patient after liver transplantation. In cases of violation of the blood flow in the portal vein CT angiography performance is needed. Percutaneous transhepatic stenting of portal vein is a minimally invasive and highly effective method of correction of portal hypertension. Antiplatelet therapy and platelet aggregation control are the prerequisites for successful stent function.

scholarly journals Case Report of Portal Vein Stent Placement for Portal Vein Stenosis due to Recurrence of Hilar Cholangiocarcinoma

2013 ◽  
Vol 74 (10) ◽  
pp. 2879-2884 ◽  
Author(s):  
Yosuke OHNO ◽  
Hirofumi KAMATI ◽  
Yosuke TURUGA ◽  
Hideki YOKO ◽  
Toshiya KAMIYAMA ◽  
...  
Keyword(s):  
Case Report ◽  
Portal Vein ◽  
Stent Placement ◽  
Hilar Cholangiocarcinoma ◽  
Portal Vein Stenosis ◽  
Vein Stenosis

Stent Placement for Portal Vein Stenosis After Pancreaticoduodenectomy

2015 ◽  
Vol 39 (9) ◽  
pp. 2315-2322 ◽  
Author(s):  
Masahide Hiyoshi ◽  
Yoshiro Fujii ◽  
Kazuhiro Kondo ◽  
Naoya Imamura ◽  
Motoaki Nagano ◽  
...  
Keyword(s):  
Portal Vein ◽  
Stent Placement ◽  
Portal Vein Stenosis ◽  
Vein Stenosis

A Novel Canine Model of Portal Vein Stenosis Plus Thioacetamide Administration-Induced Cirrhotic Portal Hypertension With Hypersplenism

2011 ◽  
Vol 62 (1) ◽  
pp. 245-255 ◽  
Author(s):  
Dexin Lin ◽  
Xianbin Wu ◽  
Xiaoke Ji ◽  
Qiyu Zhang ◽  
YuanWei Lin ◽  
...  
Keyword(s):  
Portal Hypertension ◽  
Portal Vein ◽  
Canine Model ◽  
Portal Vein Stenosis ◽  
Vein Stenosis

Effect of Long-Term Octreotide and Isosorbide Dinitrate on Haemodynamics in Rats with Portal Vein Stenosis

1998 ◽  
Vol 94 (6) ◽  
pp. 645-650 ◽  
Author(s):  
Han-Chieh Lin ◽  
Yi-Tsau Huang ◽  
Yuh-Ren Cheng ◽  
Ming-Chih Hou ◽  
Fa-Yauh Lee ◽  
...  
Keyword(s):  
Portal Hypertension ◽  
Portal Vein ◽  
Isosorbide Dinitrate ◽  
Portal Pressure ◽  
Vehicle Group ◽  
Hyperdynamic Circulation ◽  
Portal Vein Stenosis ◽  
Term Administration ◽  
Vein Stenosis

1. Both octreotide and isosorbide dinitrate have been shown to have portal hypotensive effects in animals with portal hypertension. Moreover, in both animals and humans with portal hypertension, the reduction of portal pressure was enhanced when nitrovasodilators were combined with propranolol or vasopressin. The present study was undertaken to evaluate the effect of long-term administration of octreotide and isosorbide dinitrate on haemodynamics in rats with portal vein stenosis. 2. Portal hypertension was induced by portal vein stenosis. Portal hypertensive rats were allocated into one of four groups (eight rats in each group): vehicle group, octreotide group (100 μg/kg via subcutaneous injection every 12 h), isosorbide dinitrate group (5 mg/kg via gastric gavage every 12 h) and combined treatment group. Drug was given for eight consecutive days, starting 1 day before surgery. Haemodynamic values were measured using a radioactive microsphere technique. 3. Long-term octreotide treatment decreased portal pressure and improved the hyperdynamic circulation. In contrast, long-term administration of isosorbide dinitrate reduced portal pressure but did not ameliorate vasodilatation. A combination of octreotide and isosorbide dinitrate improved the hyperdynamic circulation with a reduction of portal pressure. In addition, the mean value of portal pressure after combination treatment was significantly lower than in rats receiving octreotide alone. 4. These results showed that, in rats with portal hypertension, long-term combined administration of octreotide and isosorbide dinitrate improved the hyperdynamic circulation together with a more profound reduction of portal pressure than rats receiving octreotide alone.

Effects of pentobarbital sodium anesthesia on splanchnic hemodynamics of normal and portal-hypertensive rats

1985 ◽  
Vol 249 (4) ◽  
pp. G528-G532 ◽  
Author(s):  
S. S. Lee ◽  
C. Girod ◽  
D. Valla ◽  
P. Geoffroy ◽  
D. Lebrec
Keyword(s):  
Blood Flow ◽  
Cardiac Output ◽  
Portal Hypertension ◽  
Portal Vein ◽  
Regional Blood Flow ◽  
Hypertensive Rats ◽  
Pentobarbital Sodium ◽  
Portal Vein Stenosis ◽  
Pentobarbital Sodium Anesthesia ◽  
Vein Stenosis

To determine the effect of pentobarbital sodium anesthesia on the rat with portal hypertension due to portal vein stenosis, four groups of rats were studied. Cardiac output and regional blood flow were measured by radioactive microspheres in anesthetized and conscious sham-operated and portal-hypertensive rats. Anesthesia markedly decreased cardiac output in both sham-operated (109.7 +/- 4.6 vs. 77.8 +/- 1.4 ml/min, P less than 0.001) and portal-hypertensive rats (130.1 +/- 7.6 vs. 93.8 +/- 5.3 ml/min, P less than 0.01). In spite of this diminution in cardiac output, pentobarbital did not significantly change absolute blood flow values of splanchnic organs in either group. However, the fractions of cardiac output perfusing the splanchnic organs were significantly increased by pentobarbital in both groups because of the decrease in cardiac output: sham operated, anesthetized, 22.86 +/- 1.19% vs. conscious, 14.83 +/- 1.02%, P less than 0.001; and portal hypertensive, anesthetized, 26.67 +/- 0.71% vs. conscious, 19.07 +/- 1.44%, P less than 0.001. The hyperdynamic circulation of the portal vein-stenosed rat compared with the sham-operated rat continued to manifest itself with significantly increased portal pressure, cardiac output, and splanchnic blood flow, whether the animal was anesthetized or awake. We conclude that, despite marked hemodynamic changes induced by pentobarbital, the rat with portal vein stenosis remains a useful experimental model of portal hypertension.

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