We evaluated vancomycin pharmacokinetics in pediatric LT recipients and developed a population pharmacokinetics model by considering various factors that might account for alterations in vancomycin pharmacokinetics. Our analyses revealed that lower serum creatinine levels and a shorter duration from the day of LT were associated with higher vancomycin clearance and led to subtherapeutic drug exposure.
Chronic Hepatic Venous Ischemia Secondary to Venous Outflow Insufficiency Causes Chronic Rejection in Pediatric Liver Transplant Recipients
