Phenobarbital Sodium

2021 ◽  
pp. 1275-1278
Keyword(s):  
1988 ◽  
Vol 37 (3) ◽  
pp. 311-316
Author(s):  
Meiwei XIAN ◽  
Satoshi INOUE ◽  
Naochika MATSUNUMA ◽  
Naoaki GOTO ◽  
Kôsaku FUJIWARA

1986 ◽  
Vol 72 (2) ◽  
pp. 125-128 ◽  
Author(s):  
Antonio Cavaliere ◽  
Andrea Bufalari ◽  
Rino Vitali

The carcinogenic and cocarcinogenic action of phenobarbital sodium was investigated in adult BALB/c mice of both sexes when administered alone at a concentration of 0.05 % in drinking water for life or after the animals had been treated with a single hydrazine sulphate dose of 5.65 mg. The results demonstrated that phenobarbital sodium is not carcinogenic in this strain of mice, but, since a single dose of hydrazine sulphate was carcinogenic, does not clarify whether it is a cocarcinogen in the lung.


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