scholarly journals Has the COVID-19 pandemic affected the management of brain tumours? A systematic review and meta-analysis protocol

Author(s):  
Mohammed Azab ◽  
Sherief Ghozy ◽  
Abdulraheem Alomari ◽  
Ahmed Azzam
2021 ◽  
pp. 1-9
Author(s):  
Clifford Waller ◽  
Bahram Sangelaji ◽  
Peter Lamb ◽  
Suzanne Kuys ◽  
Stephanie J. Woodley

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Rosemond Qian-Xiu Tan ◽  
Wai Tak Victor Li ◽  
Wing-Zi Shum ◽  
Sheung Chit Chu ◽  
Hang-Long Li ◽  
...  

Abstract Background The coronavirus disease 2019 (COVID-19) pandemic has caused recurring and major outbreaks in multiple human populations around the world. The plethora of clinical presentations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been described extensively, of which olfactory dysfunction (OD) was established as an important and common extrapulmonary manifestation of COVID-19 infection. The aim of this protocol is to conduct a systematic review and meta-analysis on peer-reviewed articles which described clinical data of OD in COVID-19 patients. Methods This research protocol has been prospectively registered with the Prospective Register of Systematic Reviews (PROSPERO; CRD42020196202). CINAHL, ClinicalTrials.gov, Cochrane Central, EMBASE, MEDLINE and PubMed, as well as Chinese medical databases China National Knowledge Infrastructure (CNKI), VIP and WANFANG, will be searched using keywords including ‘COVID-19’, ‘coronavirus disease’, ‘2019-nCoV’, ‘SARS-CoV-2’, ‘novel coronavirus’, ‘anosmia’, ‘hyposmia’, ‘loss of smell’, and ‘olfactory dysfunction’. Systematic review and meta-analysis will be conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and the Meta-analyses Of Observational Studies in Epidemiology (MOOSE) guidelines. Articles will be screened according to pre-specified inclusion and exclusion criteria to extract studies that include new clinical data investigating the effect of COVID-19 on olfactory dysfunction. Included articles will be reviewed in full; data including patient demographics, clinical characteristics of COVID-19-related OD, methods of olfactory assessment and relevant clinical outcomes will be extracted. Statistical analyses will be performed using the Comprehensive Meta-Analysis version 3. Discussion This systematic review and meta-analysis protocol will aim to collate and synthesise all available clinical evidence regarding COVID-19-related OD as an important neurosensory dysfunction of COVID-19 infection. A comprehensive search strategy and screening process will be conducted to incorporate broad clinical data for robust statistical analyses and representation. The outcome of the systematic review and meta-analysis will aim to improve our understanding of the symptomatology and clinical characteristics of COVID-19-related OD and identify knowledge gaps in its disease process, which will guide future research in this specific neurosensory defect. Systematic review registration PROSPERO registration number: CRD42020196202.


2017 ◽  
Vol 6 (1) ◽  
Author(s):  
Mauro Elias Mesko ◽  
Brian Hutton ◽  
Jovito Adiel Skupien ◽  
Rafael Sarkis-Onofre ◽  
David Moher ◽  
...  

2018 ◽  
Vol 75 (3) ◽  
pp. 676-682 ◽  
Author(s):  
Todd M. Ruppar ◽  
Pamela S. Cooper ◽  
E. Diane Johnson ◽  
Barbara Riegel

protocols.io ◽  
2020 ◽  
Author(s):  
Takeshi Yamashina ◽  
Noboru Hanaoka ◽  
Takeshi Setoyama ◽  
Masahiro Banno ◽  
Jun Watanabe ◽  
...  

protocols.io ◽  
2020 ◽  
Author(s):  
Jun Watanabe ◽  
Takanori Sano ◽  
Takeshi Kanno ◽  
Kotani Kazuhiko ◽  
Atsushi Masamune ◽  
...  

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