Novel resistance-associated mutations of thymidine kinase and DNA polymerase genes of herpes simplex virus type 1 and type 2

Antiviral Therapy ◽

10.3851/imp1870 ◽

2011 ◽

Vol 16 (8) ◽

pp. 1297-1308 ◽

Author(s):

Andreas Sauerbrei ◽

Kathrin Bohn ◽

Albert Heim ◽

Jörg Hofmann ◽

Benedikt Weiβbrich ◽

...

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Thymidine Kinase ◽

Dna Polymerase ◽

Herpes Simplex Virus Type ◽

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Hydroxyurea enhances the activity of acyclovir and cidofovir against herpes simplex virus type 1 resistant strains harboring mutations in the thymidine kinase and/or the DNA polymerase genes

Antiviral Research ◽

10.1016/j.antiviral.2007.08.009 ◽

2008 ◽

Vol 77 (1) ◽

pp. 77-80 ◽

Author(s):

Yan Sergerie ◽

Guy Boivin

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Thymidine Kinase ◽

Dna Polymerase ◽

Herpes Simplex Virus Type ◽

Resistant Strains ◽

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Properties of Herpes simplex virus type 1 and type 2 DNA polymerase

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis ◽

10.1016/0005-2787(80)90234-8 ◽

1980 ◽

Vol 609 (2) ◽

pp. 232-245 ◽

Author(s):

Michael Ostrander ◽

Yung-Chi Cheng

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Dna Polymerase ◽

Herpes Simplex Virus Type ◽

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Nucleotide sequence of the DNA polymerase gene of herpes simplex virus type 2 and comparison with the type 1 counterpart

Gene ◽

10.1016/0378-1119(87)90039-4 ◽

1987 ◽

Vol 52 (2-3) ◽

pp. 129-137 ◽

Author(s):

Tsurumi Tatsuya ◽

Maeno Koichiro ◽

Nishiyama Yukihiro

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Nucleotide Sequence ◽

Dna Polymerase ◽

Herpes Simplex Virus Type ◽

Polymerase Gene ◽

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A RATIONAL APPROACH TO THE DEVELOPMENT OF ANTIVIRAL CHEMOTHERAPY: ALTERNATIVE SUBSTRATES OF HERPES SIMPLEX VIRUS TYPE 1 (HSV-1) AND TYPE 2 (HSV-2) THYMIDINE KINASE (TK)

Annals of the New York Academy of Sciences ◽

10.1111/j.1749-6632.1977.tb21992.x ◽

1977 ◽

Vol 284 (1 Third Confere) ◽

pp. 594-598 ◽

Author(s):

Yung-Chi Cheng

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Thymidine Kinase ◽

Herpes Simplex Virus Type ◽

Rational Approach ◽

Antiviral Chemotherapy ◽

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Heterogeneity and Evolution of Thymidine Kinase and DNA Polymerase Mutants of Herpes Simplex Virus Type 1: Implications for Antiviral Therapy

The Journal of Infectious Diseases ◽

10.1093/infdis/jit019 ◽

2013 ◽

Vol 207 (8) ◽

pp. 1295-1305 ◽

Author(s):

Graciela Andrei ◽

Aspasia Georgala ◽

Dimitri Topalis ◽

Pierre Fiten ◽

Michel Aoun ◽

...

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Antiviral Therapy ◽

Thymidine Kinase ◽

Dna Polymerase ◽

Herpes Simplex Virus Type ◽

Simplex Virus ◽

Polymerase Mutants

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Combination of Azidothymidine (AZT) and (E)-5-(2-Bromovinyl)-2'-deoxyuridine (BVDU) Inhibits the Replication of Herpes Simplex Virus Type 1 (HSV-1) and Type 2 (HSV-2) and Varicella Zoster Virus (VZV) Strains That Are Deficient in the Expression of the Viral Thymidine Kinase (tk)

Nucleosides Nucleotides & Nucleic Acids ◽

10.1080/15257779508012427 ◽

1995 ◽

Vol 14 (3) ◽

pp. 559-562 ◽

Author(s):

G. Andrei ◽

R. Snoeck ◽

J. Balzarini ◽

E. De Clercq

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Varicella Zoster Virus ◽

Thymidine Kinase ◽

Herpes Simplex Virus Type ◽

Varicella Zoster ◽

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Ribonucleotide reductase of herpes simplex virus type 2 resembles that of herpes simplex virus type 1.

Journal of Virology ◽

10.1128/jvi.52.3.981-983.1984 ◽

1984 ◽

Vol 52 (3) ◽

pp. 981-983 ◽

Author(s):

D R Averett ◽

P A Furman ◽

T Spector

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Ribonucleotide Reductase ◽

Herpes Simplex Virus Type ◽

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Effect of Phosphorothioate Homo-oligodeoxy nucleotides on Herpes Simplex Virus Type 2-induced DNA Polymerase

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)60494-6 ◽

1989 ◽

Vol 264 (19) ◽

pp. 11521-11526

Author(s):

W Y Gao ◽

C A Stein ◽

J S Cohen ◽

G E Dutschman ◽

Y C Cheng

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Dna Polymerase ◽

Herpes Simplex Virus Type ◽

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Phosphorylation of four acyclic guanosine analogs by herpes simplex virus type 2 thymidine kinase.

Antimicrobial Agents and Chemotherapy ◽

10.1128/aac.25.4.524 ◽

1984 ◽

Vol 25 (4) ◽

pp. 524-526 ◽

Author(s):

A Larsson ◽

P Z Tao

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Thymidine Kinase ◽

Herpes Simplex Virus Type ◽

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Tubular Structures in Mixed Infection with Herpes Simplex Virus Type 1 and Type 2

Journal of General Virology ◽

10.1099/0022-1317-51-1-189 ◽

1980 ◽

Vol 51 (1) ◽

pp. 189-193

Author(s):

T. Iwasaka ◽

R. Mori ◽

H. Oda

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Mixed Infection ◽

Herpes Simplex Virus Type ◽

Tubular Structures ◽

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