PF‑114, a novel selective inhibitor of BCR‑ABL tyrosine kinase, is a potent inducer of apoptosis in chronic myelogenous leukemia cells

Selective Inhibitor ◽

Myelogenous Leukemia ◽

Leukemia Cells ◽

Potent Inducer ◽

Abl Tyrosine Kinase ◽

Selective induction of apoptosis in Philadelphia chromosome-positive chronic myelogenous leukemia cells by an inhibitor of BCR–ABL tyrosine kinase, CGP 57148

Cell Death and Differentiation ◽

10.1038/sj.cdd.4400400 ◽

1998 ◽

Vol 5 (8) ◽

pp. 710-715 ◽

Cited By ~ 96

Author(s):

Shingo Dan ◽

Mikihiko Naito ◽

Takashi Tsuruo

Keyword(s):

Tyrosine Kinase ◽

Philadelphia Chromosome ◽

Myelogenous Leukemia ◽

Leukemia Cells ◽

Abl Tyrosine Kinase ◽

Induction Of Apoptosis ◽

Chronic Myelogenous Leukemia Cells ◽

Philadelphia Chromosome Positive

Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR–ABL tyrosine kinase

Nature Medicine ◽

10.1038/84683 ◽

2001 ◽

Vol 7 (2) ◽

pp. 228-234 ◽

Cited By ~ 224

Author(s):

Paolo Vigneri ◽

Jean Y. J. Wang

Keyword(s):

Tyrosine Kinase ◽

Myelogenous Leukemia ◽

Leukemia Cells ◽

Abl Tyrosine Kinase ◽

Induction Of Apoptosis ◽

Targeting PFKFB3 sensitizes chronic myelogenous leukemia cells to tyrosine kinase inhibitor

Oncogene ◽

10.1038/s41388-018-0157-8 ◽

2018 ◽

Vol 37 (21) ◽

pp. 2837-2849 ◽

Cited By ~ 10

Author(s):

Yu Zhu ◽

Luo Lu ◽

Chun Qiao ◽

Yi Shan ◽

Huapeng Li ◽

...

Keyword(s):

Tyrosine Kinase ◽

Kinase Inhibitor ◽

Myelogenous Leukemia ◽

Leukemia Cells ◽

Faculty Opinions recommendation of Targeting PFKFB3 sensitizes chronic myelogenous leukemia cells to tyrosine kinase inhibitor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.732811511.793583303 ◽

2021 ◽

Author(s):

Daniela Krause

Keyword(s):

Tyrosine Kinase ◽

Kinase Inhibitor ◽

Myelogenous Leukemia ◽

Leukemia Cells ◽

SAHA and S116836, a novel tyrosine kinase inhibitor, synergistically induce apoptosis in imatinib-resistant chronic myelogenous leukemia cells

Cancer Biology & Therapy ◽

10.4161/cbt.28931 ◽

2014 ◽

Vol 15 (7) ◽

pp. 951-962 ◽

Cited By ~ 13

Author(s):

Qiangui Bu ◽

Lijing Cui ◽

Juan Li ◽

Xin Du ◽

Waiyi Zou ◽

...

Keyword(s):

Tyrosine Kinase ◽

Kinase Inhibitor ◽

Myelogenous Leukemia ◽

Leukemia Cells ◽

Imatinib Resistant ◽

FTY720 induces apoptosis of chronic myelogenous leukemia cells via dual activation of BIM and BID and overcomes various types of resistance to tyrosine kinase inhibitors

APOPTOSIS ◽

10.1007/s10495-013-0882-y ◽

2013 ◽

Vol 18 (11) ◽

pp. 1437-1446 ◽

Cited By ~ 20

Author(s):

Miki Kiyota ◽

Junya Kuroda ◽

Mio Yamamoto-Sugitani ◽

Yuji Shimura ◽

Ryuko Nakayama ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Myelogenous Leukemia ◽

Leukemia Cells ◽

Chronic Myelogenous Leukemia Cells ◽

Dual Activation

miR-217 sensitizes chronic myelogenous leukemia cells to tyrosine kinase inhibitors by targeting pro-oncogenic anterior gradient 2

Experimental Hematology ◽

10.1016/j.exphem.2018.09.001 ◽

2018 ◽

Vol 68 ◽

pp. 80-88.e2 ◽

Cited By ~ 5

Author(s):

Bin Pan ◽

Jing Yang ◽

Xiangmin Wang ◽

Kailin Xu ◽

Takayuki Ikezoe

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Myelogenous Leukemia ◽

Leukemia Cells ◽

Abstract 5892: miR-217 sensitizes chronic myelogenous leukemia cells to tyrosine kinase inhibitors by targeting pro-oncogenic anterior gradient 2

10.1158/1538-7445.am2018-5892 ◽

2018 ◽

Author(s):

Bin Pan ◽

Xiangmin Wang ◽

Kailin Xu ◽

Takayuki Ikezoe

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Myelogenous Leukemia ◽

Leukemia Cells ◽

CXCR2, a novel target to overcome tyrosine kinase inhibitor resistance in chronic myelogenous leukemia cells

Biochemical Pharmacology ◽

10.1016/j.bcp.2021.114658 ◽

2021 ◽

pp. 114658

Author(s):

Ji-Hea Kim ◽

Seung-Jin Lee ◽

Ka-Won Kang ◽

Byung-Hyun Lee ◽

Yong Park ◽

...

Keyword(s):

Tyrosine Kinase ◽

Kinase Inhibitor ◽

Myelogenous Leukemia ◽

Leukemia Cells ◽

Chronic Myelogenous Leukemia Cells ◽

Novel Target ◽

Inhibitor Resistance

Inhibition of imatinib-mediated apoptosis by the caspase-cleaved form of the tyrosine kinase Lyn in chronic myelogenous leukemia cells

Leukemia ◽

10.1038/leu.2009.60 ◽

2009 ◽

Vol 23 (8) ◽

pp. 1500-1506 ◽

Cited By ~ 17

Author(s):

P Gamas ◽

S Marchetti ◽

A Puissant ◽

S Grosso ◽

A Jacquel ◽

...

Keyword(s):

Tyrosine Kinase ◽

Myelogenous Leukemia ◽

Leukemia Cells ◽