scholarly journals Osseous metaplasia with mature bone formation of the thyroid gland: Three case reports

2013 ◽  
Vol 6 (4) ◽  
pp. 977-979 ◽  
Author(s):  
JI-SUN CHUN ◽  
RAN HONG ◽  
JUNG-A KIM
Keyword(s):  
Thyroid Gland ◽  
Bone Formation ◽  
Case Reports ◽  
Osseous Metaplasia ◽  
Mature Bone

A case of osseous metaplasia in a gastric hyperplastic polyp: An unexpected finding in a common polyp

2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S69-S70
Author(s):  
Y Zhang ◽  
Y Nakanishi
Keyword(s):  
Bone Formation ◽  
Hyperplastic Polyp ◽  
Case Reports ◽  
Osseous Metaplasia ◽  
Heterotopic Bone ◽  
Heterotopic Bone Formation ◽  
Hyperplastic Polyps ◽  
History Of ◽  
Acute And Chronic Inflammation ◽  
Gastric Hyperplastic Polyp

Abstract Introduction/Objective Foveolar hyperplastic polyp is a common gastric polyp characterized by foveolar hyperplasia with erosion, acute and chronic inflammation, granulation tissue formation, and smooth muscle strands extending from the muscularis mucosae. Although foveolar hyperplastic polyps may rarely contain foci of dysplasia or invasive carcinoma, osseous metaplasia/heterotopic bone formation in foveolar hyperplastic polyps of the stomach is extremely rare with a few case reports. Methods/Case Report A 63-year-old female with a history of hypertension, sick sinus syndrome, and Hashimoto’s thyroiditis was referred to our facility for evaluation of a mass in segment eight of the liver. The liver biopsy showed a moderately differentiated adenocarcinoma, most consistent with intrahepatic cholangiocarcinoma. A screening gastrointestinal endoscopy revealed a 7-mm sessile polyp in the antrum. The polyp was removed with a cold snare. No other abnormalities were identified in the stomach. Sections of the polyp showed fragments of antral-type gastric mucosa with foveolar hyperplasia, erosion, acute and chronic inflammation, and focal granulation tissue formation. In addition, multiple foci of woven bone formation without bone marrow surrounding dilated gastric foveolae were identified. No Helicobacter infection, intestinal metaplasia, dysplasia or malignancy was identified histologically. Osseous metaplasia/heterotopic bone formation is a well-known finding reported in various neoplastic and non- neoplastic conditions. However, osseous metaplasia in foveolar hyperplastic polyps of the stomach is extremely rare. There have been only four previous case reports published in English language. Our current case shows clinicopathologic features similar to those of the previous case reports including the findings of small-sized polyp found incidentally in middle-aged patients with no clinical history of hypercalcemia or any other abnormalities causing heterotopic bone formation. Results (if a Case Study enter NA) N/A Conclusion Although the pathogenesis of osseous metaplasia in a gastric hyperplastic polyp remains unknown, the finding of osseous metaplasia in a gastric hyperplastic polyp is very intriguing.

scholarly journals Gastric gastrointestinal stromal tumor with osseous differentiation and stromal calcification: A case report and review of literature

2017 ◽  
Vol 5 ◽  
pp. 2050313X1774631 ◽  
Author(s):  
Haneen Al-Maghrabi ◽  
Abdelrazak Meliti
Keyword(s):  
Case Report ◽  
Bone Formation ◽  
Gastrointestinal Stromal Tumor ◽  
Gastrointestinal Stromal Tumors ◽  
Gastric Wall ◽  
Stromal Tumor ◽  
Osseous Metaplasia ◽  
Gastrointestinal Malignancies ◽  
Stromal Tumors ◽  
Mature Bone

Gastrointestinal stromal tumors are the most common primary mesenchymal tumors of the gastrointestinal tract accounting for 0.1%–3.0% of all gastrointestinal malignancies. The stomach is the most common site (60%) followed by the small bowel (30%–35%) particularly jejunum and ileum, colorectum (5%) and rarely affect esophagus and appendix. Most gastrointestinal stromal tumors arise sporadically, however, less commonly they develop in association with various clinical syndromes like Carney triad, Carney–Stratakis syndrome, familial gastrointestinal stromal tumor syndrome and neurofibromatosis type1 (NF1). We report a 65-year-old male patient presented with gastric mass (7.5 × 4.5 × 3.5 cm) arising from the posterior gastric wall. Histologic examination revealed neoplastic proliferation of spindled and epithelioid cells with focal plexiform pattern and low mitotic activity 3/50 HPF. No evidence of cytological atypia, abnormal mitosis or necrosis. Interestingly enough, there were focal areas of mature bone formation/osseous differentiation associated with calcification. The tumor cells were strongly positive for CD117, DOG1 with focal immunoreactivity against CD34. The morphologic features and the immunoprofile were diagnostic of gastrointestinal stromal tumor. Herein, we present a rare case of gastric gastrointestinal stromal tumor with mature bone formation, osseous metaplasia and calcification. To the best of our knowledge, this is the second case report of gastric gastrointestinal stromal tumor with osseous differentiation and mature bone formation.

Dental Implants and Plasma Rich in Fibrine: A Wide Literary Review

2021 ◽  
pp. 34-41
Author(s):  
Carlos Fernando Almeida da Silva ◽  
Tayná Toder Santos ◽  
Idiberto José Zotarelli Filho ◽  
Elias Naim Kassis
Keyword(s):  
Bone Formation ◽  
Maxillary Sinus ◽  
Dental Implants ◽  
Case Reports ◽  
Bone Grafts ◽  
Sinus Surgery ◽  
Autogenous Bone ◽  
Platelet Concentrates ◽  
Surgical Access ◽  
Short Implants

Introduction: When a dental element is lost in the posterior region of the maxilla, there is natural reabsorption of the alveolar process and at the same time there will be pneumatization of the maxillary sinus. It will increase its volume towards the place where the roots existed and this will often make it difficult or impossible to restore implants in place. For this reason, the procedure for elevating the floor of the maxillary sinus or short implants should be performed when possible. In this context, allogeneic, xenogenous, and alloplastic bone grafts are an alternative for the treatment of bone defects in the jaws, since they avoid the need for a second surgical access. However, due to the need for processing to eliminate antigenic components, these grafts are only osteoconductive with a lower bone formation potential compared to autogenous bone grafts. Also, in this context, in the last 20 years, platelet concentrates have been proposed as regenerative materials in tissue regeneration procedures. Among the platelet concentrates proposed in the literature, PRP and FRP are found to act as autogenous platelet aggregates with osteoinductive properties. Objective: The present study aimed to conduct a wide literature review on maxillary sinus surgery using fibrin-rich plasma. Methods: Experimental and clinical studies (case reports, retrospective, prospective and randomized) with qualitative and/or quantitative analysis were included. Results: The total of 48 articles were found involving Maxillary sinus surgery, Fibrin-rich plasma, and Biomaterials, of which 22 were selected to compose the present study. Conclusion: Based on the literary findings, it was shown that the FRP is favorable for bone formation processes for dental implants, especially when combined with xenografts.

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