scholarly journals Case of Giant Cell Arteritis After SARS-CoV-2 Vaccination: A Particular Phenotype?

2021 ◽  
pp. jrheum.210724
Author(s):  
Agathe Sauret ◽  
Julien Stievenart ◽  
Perrine Smets ◽  
Louis Olagne ◽  
Benedicte Guelon ◽  
...  

We read with great interest the article by Mehta et al about the similarities and discriminators between giant cell arteritis (GCA) and the coronavirus disease 2019 (COVID-19).1 Viruses have been suspected to be implicated in the pathogenesis of GCA, especially the varicella zoster virus,2 but a clear association has not been confirmed.3

2016 ◽  
Vol 73 (2) ◽  
pp. 239 ◽  
Author(s):  
Maria A. Nagel ◽  
Teresa White ◽  
Don Gilden

2019 ◽  
Vol 43 (3) ◽  
pp. 159-170 ◽  
Author(s):  
Rochella A. Ostrowski ◽  
Sheela Metgud ◽  
Rodney Tehrani ◽  
Walter M. Jay

2016 ◽  
Vol 75 (Suppl 2) ◽  
pp. 794.2-794
Author(s):  
F. Muratore ◽  
S. Croci ◽  
I. Tamagnini ◽  
A. Zerbini ◽  
L. Belloni ◽  
...  

2019 ◽  
Vol 46 (12) ◽  
pp. 1614-1618 ◽  
Author(s):  
Isaac H. Solomon ◽  
William P. Docken ◽  
Robert F. Padera

Objective.A variety of infectious agents, including varicella zoster virus (VZV), have been hypothesized to play a role in the pathogenesis of giant cell arteritis (GCA). The detectability of the virus in patients with GCA is debatable. To further investigate an association between GCA and VZV infection, 10 years of GCA cases were evaluated for VZV by immunohistochemistry (IHC).Methods.All temporal artery biopsies and ascending aortic resections positive for GCA from 2007 to 2017 at Brigham and Women’s Hospital were immunostained using a VZV antibody cocktail (SG1-1, SG1-SG4, NCP-1, and IE-62).Results.Forty-one temporal artery biopsies and 47 ascending aortic resections positive for GCA were identified, all of which were found to be negative for VZV by IHC. Twelve temporal artery biopsies in this cohort were previously analyzed by unbiased metagenomics sequencing and were negative for VZV DNA.Conclusion.These results argue against a clinically relevant association between VZV infection and GCA, and support neither routine testing for VZV nor treatment with antiviral drugs.


2017 ◽  
Vol 8 ◽  
Author(s):  
Christien Rondaan ◽  
Kornelis S. M. van der Geest ◽  
Elisabeth Eelsing ◽  
Annemieke M. H. Boots ◽  
Nicolaas A. Bos ◽  
...  

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