Chapter 10. Assessing the socioeconomic impact of ECOWAS CET implementation in Niger

Author(s):  
Ismaël Fofana
Keyword(s):  
Author(s):  
Klaus Schwab

The rapid pace of technological developments played a key role in the previous industrial revolutions. However, the fourth industrial revolution (Industry 4.0) and its embedded technology diffusion progress is expected to grow exponentially in terms of technical change and socioeconomic impact. Therefore, coping with such transformation require a holistic approach that encompasses innovative and sustainable system solutions and not just technological ones. In this article, we propose a framework that can facilitate the interaction between technological and social innovation to continuously come up with proactive, and hence timely, sustainable strategies. These strategies can leverage economic rewards, enrich society at large, and protect the environment. The new forthcoming opportunities that will be generated through the next industrial wave are gigantic at all levels. However, the readiness for such revolutionary conversion require coupling the forces of technological innovation and social innovation under the sustainability umbrella.


2018 ◽  
Vol 24 (19) ◽  
pp. 2055-2075 ◽  
Author(s):  
Kalliopi Kostelidou ◽  
Ilias Matis ◽  
Georgios Skretas

Neurodegenerative Diseases (ND) are a major threat to the aging population and the lack of a single preventive or disease-modifying agent only serves to increase their impact. In the past few years, protein misfolding and the subsequent formation of neurotoxic oligomeric/aggregated protein species have emerged as a unifying theme underlying the pathology of these complex diseases. Recently developed microbial genetic screens and selection systems for monitoring ND-associated protein misfolding have allowed the establishment of highthroughput assays for the identification of cellular factors and processes that are important mediators of NDassociated proteotoxicities. In addition, such systems have facilitated the discovery of synthetic and natural compounds with the ability to rescue the misfolding and the associated pathogenic effects of aggregation-prone proteins associated with NDs. This review outlines such available systems in bacteria and yeast, whose usage will likely accelerate the pre-clinical discovery process for effective drugs against a variety of NDs with high socioeconomic impact.


2014 ◽  
Vol 76 (1) ◽  
pp. 57-64 ◽  
Author(s):  
M Carien de Beer ◽  
Cori Ham ◽  
Dirk W Längin ◽  
Francois Theron

2021 ◽  
pp. 427-435
Author(s):  
M. Chandrasekar ◽  
T. Senthil Muthu Kumar ◽  
K. Senthilkumar ◽  
S.M. Sapuan ◽  
R.A. Ilyas ◽  
...  
Keyword(s):  

1999 ◽  
Vol 38 (4) ◽  
pp. 277-284 ◽  
Author(s):  
W. M. Ngecu ◽  
E. M. Mathu

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