In this paper, we investigate a predator-prey system with Beddington–DeAngelis (B-D) functional response in a spatially degenerate heterogeneous environment. First, for the case of the weak growth rate on the prey (
λ
1
Ω
<
a
<
λ
1
Ω
0
), a priori estimates on any positive steady-state solutions are established by the comparison principle; two local bifurcation solution branches depending on the bifurcation parameter are obtained by local bifurcation theory. Moreover, the demonstrated two local bifurcation solution branches can be extended to a bounded global bifurcation curve by the global bifurcation theory. Second, for the case of the strong growth rate on the prey (
a
>
λ
1
Ω
0
), a priori estimates on any positive steady-state solutions are obtained by applying reduction to absurdity and the set of positive steady-state solutions forms an unbounded global bifurcation curve by the global bifurcation theory. In the end, discussions on the difference of the solution properties between the traditional predator-prey system and the predator-prey system with a spatial degeneracy and B-D functional response are addressed.
Uniqueness of positive steady state solutions to the unstirred chemostat model with external inhibitor
