Late Stage of Biosynthesis of Intermolecular Diels-Alder Type Adducts in Morus alba L. Cell Cultures

Heterocycles ◽  
1999 ◽  
Vol 51 (2) ◽  
pp. 231 ◽  
Author(s):  
Taro Nomura ◽  
Yoshio Hano ◽  
Shinichi Ueda
Keyword(s):  
Cell Cultures ◽  
Late Stage ◽  
Diels Alder ◽  
Morus Alba ◽  
L Cell

scholarly journals Constituents of Morus alba L. cell cultures. 1 Structures of four new natural Diels-Alder type adducts, kuwanons J, Q, R, and V.

1986 ◽  
Vol 34 (6) ◽  
pp. 2471-2478 ◽  
Author(s):  
JUNKO IKUTA(nee OHTA) ◽  
TOSHIO FUKAI ◽  
TARO NOMURA ◽  
SINICHI UEDA
Keyword(s):  
Cell Cultures ◽  
Diels Alder ◽  
Morus Alba ◽  
L Cell

Morusalisins A-F, six new Diels-Alder type adducts, as potential PTP1B inhibitors from cell cultures of Morus alba

Fitoterapia ◽  
2020 ◽  
Vol 146 ◽  
pp. 104682
Author(s):  
Cong Su ◽  
Yangyang Duan ◽  
Jinying Tian ◽  
Jimei Liu ◽  
Kebo Xie ◽  
...  
Keyword(s):  
Cell Cultures ◽  
Diels Alder ◽  
Morus Alba ◽  
Ptp1b Inhibitors

Direct NMR evidence for the equivalent participation of L-phenylalanine and L-tyrosine in the biosynthesis of the intermolecular Diels–Alder type adducts of prenylchalcone and prenylated 2-arylbenzofuran in Morus alba cell cultures

1994 ◽  
Vol 72 (1) ◽  
pp. 12-14 ◽  
Author(s):  
Yoshio Hano ◽  
Taro Nomura ◽  
Shinichi Ueda
Keyword(s):  
Amino Acids ◽  
Cell Cultures ◽  
Nmr Spectra ◽  
Diels Alder ◽  
Morus Alba ◽  
High Yields ◽  
C Nmr

L-[3-13C]Phenylalanine and L-[3-13C]tyrosine were administered to Morus alba cell cultures, to produce intermolecular Diels–Alder type adducts of a prenylchalcone and a 2-arylbenzofuran such as chalcomoracin (1) as well as the adducts of two molecules of prenylchalcones such as kuwanon J (2) in high yields. The 13C NMR spectra of 1 and 2 isolated from the cultures revealed that both amino acids were incorporated intact into chalcomoracin (1) and kuwanon J (2). This is the first example of direct NMR evidence for the almost equivalent incorporation of phenylalanine and tyrosine into the shikimate metabolites. This finding suggests the participation of a biosynthetic route from phenylalanine via trans-cinnamate to p-coumarate and from tyrosine to p-coumarate in this plant.

Morusalones A–D, Diels–Alder Adducts with 6/7/6/6/6/6 Hexacyclic Ring Systems as Potential PTP1B Inhibitors from Cell Cultures of Morus alba

2019 ◽  
Vol 21 (23) ◽  
pp. 9463-9467
Author(s):  
Cong Su ◽  
Xiaoyu Tao ◽  
Zhen Yin ◽  
Xiaolin Zhang ◽  
Jinying Tian ◽  
...  
Keyword(s):  
Cell Cultures ◽  
Diels Alder ◽  
Morus Alba ◽  
Ring Systems ◽  
Ptp1b Inhibitors
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