Identification of Oligosaccharides in Human Milk Bound onto the Toxin A Carbohydrate Binding Site of Clostridium difficile

2016 ◽  
Vol 26 (4) ◽  
pp. 659-665 ◽  
Author(s):  
Thi Thanh Hanh Nguyen ◽  
Jong Woon Kim ◽  
Jun-Seong Park ◽  
Kyeong Hwan Hwang ◽  
Tae-Su Jang ◽  
...  
Keyword(s):  
Clostridium Difficile ◽  
Human Milk ◽  
Binding Site ◽  
Carbohydrate Binding ◽  
Toxin A ◽  
Carbohydrate Binding Site

scholarly journals Are D-manno-configured Amadori products ligands of the bacterial lectin FimH?

2015 ◽  
Vol 11 ◽  
pp. 1096-1104 ◽  
Author(s):  
Tobias-Elias Gloe ◽  
Insa Stamer ◽  
Cornelia Hojnik ◽  
Tanja M Wrodnigg ◽  
Thisbe K Lindhorst
Keyword(s):  
Molecular Docking ◽  
Binding Site ◽  
Bacterial Adhesion ◽  
Carbohydrate Binding ◽  
Amadori Products ◽  
E Coli ◽  
Type D ◽  
Amadori Rearrangement ◽  
Carbohydrate Binding Site

The Amadori rearrangement was employed for the synthesis ofC-glycosyl-type D-mannoside analogues, namely 1-propargylamino- and 1-phenylamino-1-deoxy-α-D-manno-heptopyranose. They were investigated as ligands of type 1-fimbriatedE. colibacteria by means of molecular docking and bacterial adhesion studies. It turns out that Amadori rearrangement products have a limited activity as inhibitors of bacterial adhesion because the β-C-glycosidically linked aglycone considerably hampers complexation within the carbohydrate binding site of the type 1-fimbrial lectin FimH.

scholarly journals Structure of Dioclea virgata lectin: Relations between carbohydrate binding site and nitric oxide production

Biochimie ◽  
2012 ◽  
Vol 94 (3) ◽  
pp. 900-906 ◽  
Author(s):  
Raphael Batista da Nóbrega ◽  
Bruno A.M. Rocha ◽  
Carlos Alberto A. Gadelha ◽  
Tatiane Santi-Gadelha ◽  
Alana F. Pires ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Binding Site ◽  
Carbohydrate Binding ◽  
Nitric Oxide Production ◽  
Oxide Production ◽  
Carbohydrate Binding Site

scholarly journals Low or No Inhibitory Potency of the Canonical Galectin Carbohydrate-binding Site by Pectins and Galactomannans

2016 ◽  
Vol 291 (25) ◽  
pp. 13318-13334 ◽  
Author(s):  
John Stegmayr ◽  
Adriana Lepur ◽  
Barbro Kahl-Knutson ◽  
Matilde Aguilar-Moncayo ◽  
Anatole A. Klyosov ◽  
...  
Keyword(s):  
Binding Site ◽  
Carbohydrate Binding ◽  
Inhibitory Potency ◽  
Carbohydrate Binding Site

scholarly journals 1P059 Typical structure of carbohydrate binding site

2004 ◽  
Vol 44 (supplement) ◽  
pp. S44
Author(s):  
C. Shionyu-Mitsuyama ◽  
T. Shirai
Keyword(s):  
Binding Site ◽  
Carbohydrate Binding ◽  
Typical Structure ◽  
Carbohydrate Binding Site
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