Use of Technetium-99m-Labeled Lipophilic Complex of Methoxy-Isobutyl-Isonitrile and Iopromide Radiopaque Substance to Assess the Severity of Coronary Atherosclerosis in Patients with Coronary Heart Disease at Mild Disorders of Myocardial Perfusion

2015 ◽  
Vol 1084 ◽  
pp. 527-531
Author(s):  
Konstantin V. Zavadovsky ◽  
Marina O. Gulya ◽  
Yuriy B. Lishmanov ◽  
Vera V. Verkhoturova

In this study we used technetium-99m-labeled lipophilic complex of methoxy-isobutyl-isonitrile (99mTc-MIBI) and iopromide to assess coronary atherosclerosis in patients with coronary artery disease (CAD). The study included 33 patients with CAD who underwent myocardial perfusion scintigraphy with 99mTc-MIBI and computed tomography angiography (MDCTA) with iopromide. Patients who have comparable with the population-wide level risk of coronary events are characterized by the presence of borderline and significant stenosis 83% and 86%, respectively. 99mTc-MIBI and iopromide can be used to assess the severity of coronary atherosclerosis in patients with CAD.

Author(s):  
Nikant Sabharwal ◽  
Parthiban Arumugam ◽  
Andrew Kelion

This chapter focuses on image interpretation in myocardial perfusion scintigraphy. It covers planar acquisitions, the general approach to reporting single photon emission computed tomography (SPECT) images, and both qualitative and quantitative evaluation of tomographic slices. Detail is also provided on gated SPECT and attenuation correction, as well as a range of artefacts including image, instrumentation-related, and patient-related artefacts. Information is provided on abnormal appearances in coronary artery disease, perfusion defects, and indirect markers of severe coronary artery disease. The chapter also covers interpretation in left ventricular dysfunction and appearances in non-coronary cardiac disease, and includes a section on writing a useful report.


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