scholarly journals Efficacy of Multimodal Pain Control Protocol in the Setting of Total Hip Arthroplasty

2009 ◽  
Vol 1 (3) ◽  
pp. 155 ◽  
Author(s):  
Kyung-Jae Lee ◽  
Byung-Woo Min ◽  
Ki-Cheor Bae ◽  
Chul-Hyun Cho ◽  
Doo-Hyun Kwon
2009 ◽  
Vol 91 (1) ◽  
pp. 29-37 ◽  
Author(s):  
Joseph Marino ◽  
Joseph Russo ◽  
Maureen Kenny ◽  
Robert Herenstein ◽  
Elayne Livote ◽  
...  

2019 ◽  
Vol 55 (4) ◽  
pp. 273-278
Author(s):  
Edward C. Rainville ◽  
Carl Asche ◽  
Jinma Ren ◽  
MinChul Kim ◽  
Lucas Walker ◽  
...  

Background: Achieving postsurgical pain control after total hip arthroplasty (THA) is a critical factor for successful recovery because inadequately treated pain may lead to a delay in ambulation and hospital discharge and have an adverse impact on a patient’s quality of life. Objective: This study compares the effectiveness of immediate-release local anesthetics for pain control in THA vs liposomal bupivacaine (LB) related to patient outcomes and costs of care. Methods: This is a retrospective cohort study of consecutive patients undergoing THA at 3 hospitals from January 2013 to July 2016. The control group received plain bupivacaine or ropivacaine while the study group received LB. Generalized linear models were used controlling for several patient factors. Primary measures included length of stay (LOS), hospitalization costs, pain relief, opioid use, and mobility. Secondary outcomes were discharge disposition and 30-, 60-, and 90-day readmissions. Results: One hundred and ninety-six patients were identified, with 103 as controls, 70 receiving LB, and 23 excluded. The LB group showed a decrease in LOS of 0.5 days (2.5 ± 2.6 vs 3.0 ± 2.1 days, P = .010), increased mobility on the day of surgery (27.6 ± 49.3 vs 12.5 ± 48.5 feet, P = .001) and the first day after surgery (186.8 ± 133.8 vs 155.2 ± 135.6, P = .039), and decreased hospital costs ($10 670 vs $11 351, P = .022). There were no significant differences in pain scores, opioid use, adverse events, discharge disposition, or readmissions. Study limitations include retrospective analysis, unblinded participants, and generalizability of results. Conclusions: LB provides an effective alternative to standard local anesthetics in patients undergoing THA based on improvements of inpatient parameters, LOS, and cost measures.


2018 ◽  
Vol 42 (8) ◽  
pp. 1803-1810 ◽  
Author(s):  
Maria Bautista ◽  
Meilyn Muskus ◽  
Adolfo Llinás ◽  
Guillermo Bonilla ◽  
Carlos Guerrero ◽  
...  

Medicine ◽  
2017 ◽  
Vol 96 (25) ◽  
pp. e7190 ◽  
Author(s):  
Ting-Ting Ma ◽  
Yu-Hui Wang ◽  
Yun-Feng Jiang ◽  
Cong-Bin Peng ◽  
Chao Yan ◽  
...  

2016 ◽  
Vol 31 (7) ◽  
pp. 1510-1515 ◽  
Author(s):  
Stephen W. Yu ◽  
Alessandra L. Szulc ◽  
Sharon L. Walton ◽  
Roy I. Davidovitch ◽  
Joseph A. Bosco ◽  
...  

2005 ◽  
Vol 102 (5) ◽  
pp. 1014-1022 ◽  
Author(s):  
Eugene R. Viscusi ◽  
Gavin Martin ◽  
Craig T. Hartrick ◽  
Neil Singla ◽  
Garen Manvelian ◽  
...  

Background Epidural morphine has proven analgesic efficacy in the postoperative period and is widely used. This study evaluated the efficacy of extended-release epidural morphine (EREM; DepoDur; Endo Pharmaceuticals Inc., Chadds Ford, PA; SkyePharma, Inc., San Diego, CA) in providing pain relief for 48 h after surgery. Methods Patients (n = 200) scheduled to undergo total hip arthroplasty were randomized to receive a single dose of 15, 20, or 25 mg EREM or placebo. After surgery and after asking for pain medication, patients had access to intravenous patient-controlled analgesia fentanyl for breakthrough pain as needed. Postoperative intravenous patient-controlled analgesia fentanyl use, time to first postoperative fentanyl use, pain intensity at rest and with activity, patient and surgeon ratings of pain control, and adverse events were recorded. Results All EREM dosages reduced the mean (+/- SD) fentanyl use versus placebo (510 +/- 708 vs. 2,091 +/- 1,803 microg; P < 0.0001) and delayed the median time to first dose of fentanyl (21.3 vs. 3.6 h; P < 0.0001). All EREM groups had significantly improved pain control at rest through 48 h postdose (area under the curve [0-48 h]) compared with placebo (P < 0.0005). More EREM-treated patients rated their pain control as good or very good compared with placebo (at 24 h: 90 vs. 65%, P < 0.0001; at 48 h: 83 vs. 67%, P < 0.05). No supplemental analgesia was needed in 25% of EREM-treated patients and 2% of placebo-treated patients at 48 h (P < 0.05). The safety profile of EREM was consistent with that of other epidurally administered opioid analgesics. Conclusions EREM provided significant postoperative pain relief over a 48-h period after hip surgery, without the need for indwelling epidural catheters.


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