scholarly journals Spindle Cell Carcinoma of the Tongue: A Rare Tumor in an Unusual Location

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Murat Oktay ◽  
Tuba Dilay Kokenek-Unal ◽  
Bulent Ocal ◽  
Guleser Saylam ◽  
Mehmet Hakan Korkmaz ◽  
...  

Spindle cell carcinoma is a rare biphasic tumor consisting of epithelial and mesenchymal components. Presence of this tumor type in the tongue has rarely been reported. Herein, a case of 55-year-old woman who presented with a polypoid lesion at her tongue has been reported. Surgery was performed and pathologic examination revealed a spindle cell carcinoma. We present this rare tumor with an unusual location to contribute in part to the better understanding and awareness of this rare malignancy.

Author(s):  
Amrit Kaur Kaler, Shweta C, Smitha Chandra B.C, Rajeev Naik

Spindle cell carcinoma is a rare aggressive biphasic tumor, composed of neoplastic proliferation of both epithelial (squamous) and spindle cell population. It constitutes about 1% of all oral cavity tumors 2a and is almost rare on the tongue; only few cases have been reported so far. This variant of squamous cell carcinoma, comprises major diagnostic problems due to its varied histomorphology and resemblance to sarcomatous lesion; hence diligent screening and IHC markers are mandatory for its diagnosis.


2003 ◽  
Vol 49 (5) ◽  
pp. 339-342 ◽  
Author(s):  
Fumihiro OHTAKE ◽  
Isamu KODANI ◽  
Rieko DOI ◽  
Mitugi ONDA ◽  
Masaki SUDOH ◽  
...  

2011 ◽  
Vol 23 (4) ◽  
pp. 181-185 ◽  
Author(s):  
Toshiko Mandai ◽  
Kosei Ishida ◽  
Satoshi Ito ◽  
Hiroyo Deguchi ◽  
Tsuyoshi Hata ◽  
...  

2015 ◽  
Vol 61 (12) ◽  
pp. 662-666
Author(s):  
Keita TODOROKI ◽  
Hajime MATSUMOTO ◽  
Nanae KUSHINO ◽  
Takahiro HARAGUCHI ◽  
Osamu IWAMOTO ◽  
...  

2011 ◽  
Vol 2011 ◽  
pp. 1-4
Author(s):  
Prateek Kinra ◽  
V. Srinivas ◽  
Kavita Sinha ◽  
Vibha Dutta

Spindle cell carcinoma of the tonsillar pillar is a rare malignancy. A case of spindle cell carcinoma of the anterior tonsillar pillar in a 59-year-old man is presented. A growth on the anterior tonsillar pillar, measuring9×7×6 mm, was resected. The neoplasm occurred as a complication of radiotherapy (excessive cumulative radiation dose of 60 Gray) for carcinoma larynx with a latency period of three years. Postradiation spindle cell carcinoma is an uncommon disease manifesting as sarcoma in a previously irradiated field, usually with a latent period of 5 years or more. Literature is limited to small series. Histologically, this tonsillar growth was composed of a squamous cell carcinoma (epithelial component) and a spindle cell sarcomatous component. The two components of the tumour were confirmed using the immunohistochemical staining (cytokeratin and vimentin). Further p53 positivity of the sarcomatous elements aided in ruling out radiation-induced nonmalignant changes of mesenchymal tissue. This paper discusses this rare tumour in a common setting.


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