scholarly journals A rare variant of squamous cell carcinoma of the tongue; spindle cell carcinoma Dilde nadir görülen biryassı hücreli karsinom varyantı: iğsi hücreli karsinom

2005 ◽  
Vol 58 (1) ◽  
pp. 1
Author(s):  
KÖSEOĞLU KÖSEOĞLU ◽  
Ayşe;AYVA Ayşe;AYVA ◽  
Yaşar Yaşar
Author(s):  
Amrit Kaur Kaler, Shweta C, Smitha Chandra B.C, Rajeev Naik

Spindle cell carcinoma is a rare aggressive biphasic tumor, composed of neoplastic proliferation of both epithelial (squamous) and spindle cell population. It constitutes about 1% of all oral cavity tumors 2a and is almost rare on the tongue; only few cases have been reported so far. This variant of squamous cell carcinoma, comprises major diagnostic problems due to its varied histomorphology and resemblance to sarcomatous lesion; hence diligent screening and IHC markers are mandatory for its diagnosis.


Author(s):  
Trilok C. Guleria ◽  
Shobha Mohindroo ◽  
Narender K. Mohindroo ◽  
Ramesh K. Azad

<p>Sarcomatoid (spindle cell) carcinoma is a rare variant of squamous cell carcinoma (SCC). It compromises of 2–3% of laryngeal cancers. Tumor arises from the oral cavity, tonsil, larynx and pharynx. Majority of these tumors are polypoid or pedunculated and tend to cause obstructive symptoms. These tumors are often detected at an early stage, removed by polypectomy during diagnosis and tend to have a very good prognosis. In this case report, 76 years male who presented with progressive hoarseness of his voice and pain in throat. The patient underwent direct laryngoscopy with excision of the malignant mass and received radiotherapy. </p>


ORL ◽  
2020 ◽  
Vol 82 (6) ◽  
pp. 310-317
Author(s):  
Le Chen ◽  
Qi Chen ◽  
Cai Li ◽  
Liang Zhou ◽  
Shuyi Wang ◽  
...  

<b><i>Aims:</i></b> To investigate the clinical features, treatment, and outcomes of laryngeal spindle cell carcinoma (SpCC). <b><i>Methods:</i></b> Between 2005 and 2014, patients from our hospital with SpCC of the larynx were retrospectively analyzed alongside patient data from the SEER database of America. <b><i>Results:</i></b> A total of 11 patients with SpCC of the larynx were diagnosed and underwent surgery in our hospital. All patients were male and all tumors were located in the glottis. The 3- and 5-year OS rates were both 54.5%. In the SEER database, 148 patients were diagnosed with SpCC of the larynx. The 3- and 5-year OS rates were 72.8 and 63.2%, respectively. According to the comparison of propensity score-matched analysis, the OS was longer in squamous cell carcinoma (SCC) of the larynx (<i>p</i> &#x3c; 0.0001). <b><i>Conclusion:</i></b> SpCC of the larynx is rare and typically originates in the glottis. Its prognosis is worse than that of laryngeal SCC, and surgery is a reasonable treatment strategy.


2005 ◽  
Vol 119 (3) ◽  
pp. 230-232
Author(s):  
Giancarlo Ottaviano ◽  
Gino Marioni ◽  
Rosario Marchese-Ragona ◽  
Filippo Marino ◽  
Alberto Staffieri

Synchronous laryngeal malignancies are extremely uncommon. To the best of our knowledge, only four cases of primary synchronous squamous cell carcinoma (SCC) of the larynx are available in the literature. We report the case of a 52-year-old patient with simultaneous spindle-cell carcinoma and SCC in situ of the larynx. The pathogenesis, treatment and prognosis of this rare occurrence have been discussed.


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