scholarly journals An urological cause of hypoglycaemia: A case report of the Doege-Potter syndrome

2020 ◽  
Vol 92 (4) ◽  
Author(s):  
Nuno Ramos ◽  
Rodrigo Ramos ◽  
Celso Marialva ◽  
Eduardo Silva

The Doege-Potter syndrome is a rare paraneoplastic syndrome presenting with hypoglycaemia due to ectopic secretion of insulin-like growth factor II (IGF-II) from a solitary fibrous tumor. The underlying tumor can be benign or malignant and rarely present in extrapleural sites. We describe the case of a 83-year-old male diagnosed with a Doege-Potter syndrome due to a kidney tumor.

2020 ◽  
Vol 99 (2) ◽  
pp. 95-98

Introduction: Doege-Potter syndrome is a rare syndrome characterized by hypo-insulinemic hypoglycemia. It is caused by excessive ectopic secretion of insulin-like growth factor II from a solitary fibrous tumors of intrapleural or extrapleural origin. Laboratory tests reveal low levels of C-peptide and insulin, on the contrary insulin-like growth factor II level is elevated, which is characteristic for Doege-Potter syndrome. Majority of solitary fibrous tumors present no symptomatology, recurrent hypoglycemia is relatively rare, but it may be the only clinical manifestation. The therapy is surgical, consisting of radical en-bloc tumor resection. Case report: Authors present a case report of a patient with recurrent hypoglycemia caused solely by solitary fibrous tumor. Hypoglycemia resolved immediately after surgical resection and there were no recurrences. Conclusion: Doege-Potter syndrome should be considered as the differential diagnosis in a patient with suspicion on thoracic malignancy if accompanied by features suggestive of hypoglycemia. Prolonged follow up is strongly advised because of the risk of disease recurrence, even in patients with benign solitary fibrous tumors of the pleura (SFTP).


2015 ◽  
Vol 20 (2) ◽  
pp. 439-443 ◽  
Author(s):  
Seiichi Hosaka ◽  
Hirohisa Katagiri ◽  
Jyunji Wasa ◽  
Hideki Murata ◽  
Mitsuru Takahashi

2010 ◽  
Vol 8 (3-4) ◽  
pp. 159-162 ◽  
Author(s):  
F. Yamakawa-Yokota ◽  
N. Ozaki ◽  
A. Okajima ◽  
H. Nishio ◽  
T. Nagasaka ◽  
...  

1998 ◽  
Vol 48 (1) ◽  
pp. 47-52 ◽  
Author(s):  
Yuichiro Fukasawa ◽  
Akio Takada ◽  
Masatoshi Tateno ◽  
Hidetoshi Sato ◽  
Makoto Koizumi ◽  
...  

2006 ◽  
Vol 45 (8) ◽  
pp. 525-529 ◽  
Author(s):  
Kiminori Tsuro ◽  
Hideyuki Kojima ◽  
Shingo Okamoto ◽  
Hitoshi Yoshiji ◽  
Masao Fujimoto ◽  
...  

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