scholarly journals A rare association of hepatitis A virus infection with type-1 diabetes

2016 ◽  
Vol 6 (2) ◽  
Author(s):  
Mohammed Hasosah ◽  
Alaa Bokhari ◽  
Ashraf Alsahafi ◽  
Ghassan Sukkar ◽  
Abdullah Alzaben

Patients with type-1 diabetes are predisposed to develop a spectrum of liver diseases, which includes fatty liver, steatohepatitis and cirrhosis. The association of hepatitis A infection with type-1 diabetes is extremely rare. To the best of our knowledge, our case is the first case report in children. We described a nine year-old girl who had type-1 diabetes and developed hepatitis A virus infection without complications. A review of the literature is also provided.

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Robert T. Lapp ◽  
Fedja Rochling

Hepatitis A virus is the most common acute viral hepatitis worldwide with approximately 1.5 million cases annually. Hepatitis A virus infection in general is self-limited. In rare cases, hepatitis A virus infection may cause renal failure, hemolytic anemia, and/or cholestasis. We report the first case of acute cholestatic hepatitis A virus infection complicated by hemolytic anemia, and renal failure in one patient. A 42-year-old Caucasian male presented with cholestasis, hemolytic anemia and renal failure after consuming street tacos in Central and South America while on a business trip. His protracted course required corticosteroid therapy, multiple sessions of plasma exchange, and numerous units of packed red blood cells. This case demonstrates the importance of vaccination in high-risk adults. A prompt diagnosis of acute hepatitis A virus infection is essential, as uncommon presentations may delay diagnosis leading to permanent morbidity and potentially death in fulminant cases. We also demonstrate the efficacy of treatment of cholestatic hepatitis A virus infection, hemolytic anemia, and renal failure with corticosteroids and plasma exchange.


2013 ◽  
Vol 39 (1) ◽  
Author(s):  
Annalisa di Coste ◽  
Francesco Costantino ◽  
Luigi Tarani ◽  
Vincenzo Savastano ◽  
Claudio Di Biasi ◽  
...  

2010 ◽  
Vol 42 (10) ◽  
pp. 4658-4660 ◽  
Author(s):  
G.C. Park ◽  
S. Hwang ◽  
Y.D. Yu ◽  
P.J. Park ◽  
Y.I. Choi ◽  
...  

2005 ◽  
Vol 48 (3-4) ◽  
pp. 173-175 ◽  
Author(s):  
Mehmet Yalniz ◽  
Hüseyin Ataseven ◽  
Selman Çelebı ◽  
Orhan Kürşat Poyrazoğlu ◽  
Nusret Sirma ◽  
...  

Fulminant hepatitis is a rare complication of acute hepatitis A infection. Nevertheless, the seroepidemiology of the infection is rapidly changing with the developing world, rendering more adults susceptible to the infection, in particular with more severe course. We report here fulminant hepatitis A infection with a mortal course during an epidemic period in two siblings. Although it causes a self-limited mild disease, hepatitis A virus may have a severe course including fulminant hepatitis and may lead to mortality, especially in older ages. Hence, the risk of hepatitis A virus infection and its complications should be reduced with measures of immunization and sanitation.


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