scholarly journals Diagnostic dilemma: Diagnostic algorithm in fine needle aspiration cytology of mediastinal tumors

2010 ◽  
Vol 53 (3) ◽  
pp. 395
Author(s):  
Pranab Dey
2014 ◽  
Vol 14 (4) ◽  
pp. 250 ◽  
Author(s):  
Ilker Burak Arslan ◽  
Sinan Uluyol ◽  
Selahattin Genc ◽  
Tugrul Eruyar ◽  
Suphi Bulgurcu ◽  
...  

Author(s):  
Huihong Xu ◽  
Fang Fan ◽  
Yun Gong ◽  
Xin Jing ◽  
Xiaoqi Lin ◽  
...  

Context.— Mediastinal tumors/lesions are frequently encountered in daily cytopathology practice. These lesions are accessible through endoscopic/endobronchial ultrasound-guided or computed tomography–guided fine-needle aspiration cytology and represent a wide range of primary and metastatic tumors. This often poses diagnostic challenges because of the complexity of the mediastinal anatomic structures. Tumors metastatic to mediastinal lymph nodes represent the most common mediastinal lesions and must be differentiated from primary lesions. Objective.— To provide an updated review on the fine-needle aspiration cytology of mediastinal tumors/lesions, with an emphasis on diagnostic challenges. This review encompasses thymic epithelial neoplasms, mediastinal lymphoproliferative disorders, germ cell tumors, neuroendocrine tumors, soft tissue tumors, and metastatic tumors. Differential diagnoses; useful ancillary studies, including targeted immunohistochemical panels; and diagnostic pitfalls are discussed. Data Sources.— Data were gathered from a PubMed search of peer-reviewed literature on mediastinal tumors. Data were also collected from the authors' own practices. Conclusions.— Fine-needle aspiration cytology plays a vital role in evaluation of mediastinal lesions. Being familiar with the clinical and cytomorphologic features of these lesions, appropriately triaging the diagnostic material for ancillary testing, and correlating with radiologic findings are important in arriving at correct diagnoses and guiding management.


2017 ◽  
Vol 5 (1) ◽  
pp. 22-23
Author(s):  
Suman Thapa ◽  
R. Parajuli ◽  
T. Limbu ◽  
R. Bhandari

Oncocytomas are rare benign tumors of salivary gland origin, most often seen involving the parotid gland. They should be considered as a possible diagnosis in elderly patients with slow growing, nontender and mobile parotid swelling. We report here a middle aged female with left parotid swelling that was misdiagnosed on fine needle aspiration cytology and confirmed with histopathology report. Rarity of the disease with frequent cytologic overlaps and interpreter’s inexperience account for the majority of aspiration cytology pitfalls. Therefore, aspiration cytology alone may be misguiding at times, leading to surgical over-correction and further potential complications. The ever-changing trends of mucoepidermoid carcinoma (pre-operative, fine needle aspiration cytology), pleomorphic adenoma (intraoperative) and oncocytoma (post-operative, histopathology) have created diagnostic dilemma, confusion and challenged the surgical rationale. In cases with discrepancy between clinical, cytological and pathological reports, diagnostic as well as surgical dilemma exists wherein a thorough diagnostic re-assessment and a proper surgical revision is warranted.  


2011 ◽  
Vol 40 (S2) ◽  
pp. E131-E139 ◽  
Author(s):  
Charanjeet Singh ◽  
Linjun Xie ◽  
Stephen C. Schmechel ◽  
J. Carlos Manivel ◽  
Stefan E. Pambuccian

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